Safety Data Sheet

Section 1: Chemical Product and Company Identification

Product Identification

Chemical Name: Magnesium chloride
Chemical Name: Magnesium chloride hexahydrate cryst. EMPROVE® EXPERT Ph Eur,BP,USP,JPC,FCC,E 511
Product Number: 1.05832
Item Number: 105832
Brand: Millipore

Other Names

No data available

Uses and Restrictions

Recommended Use: Pharmaceutical production and analysis
Restrictions on Use: No data available

Supplier Details

Manufacturer, Importer, or Supplier: Merck Taiwan Ltd.
Name, Address, and Phone Number: 121, Jingmao 2nd Road, Nangang District, Taipei City 115, TAIWAN
MERCK LTD.
20F., No. 121, Jingmao 2nd Road, Nangang District, Taipei City 115, Taiwan
Merck KGaA
64271 Darmstadt Germany
Phone: +49 6151 72-0
Phone: +886 2-2162-1111
Fax: +886 2-8751-6262

Emergency Contact Information

Emergency Phone Number: CHEMTREC: 00801 49 1821
CHEMTREC Taipei: +886 2 7741 4207

Section 2: Hazard Identification

Hazard Classification

According to CNS 15030: Chemical Classification and Labeling (GHS 2011), not classified as a hazardous substance or mixture.

Labeling Content

No hazard pictograms, signal words, hazard statements, or hazard prevention measures are required.

Other Hazards

No reports available.

Section 3: Composition/Information on Ingredients

Substance / Mixture: Substance
Ingredients: No hazardous ingredients.

Section 4: First-Aid Measures

First-Aid Measures for Different Exposure Routes

Inhalation: After inhalation: Move the victim to fresh air.
Skin Contact: Under skin contact: Immediately remove all contaminated clothing. Rinse skin with water/shower.
Eye Contact: After eye contact: Rinse with plenty of water. Remove contact lenses.
Ingestion: After ingestion: Have the victim drink water (up to 2 cups). Seek medical attention if discomfort occurs.

Most Important Symptoms and Effects

For most important symptoms and effects, see Section 11.

Protection for First-Aid Providers

For personal protection, see Section 8.

Notes to Physician

No data available.

Section 5: Fire-Fighting Measures

Suitable Extinguishing Media

Use extinguishing measures appropriate to the surrounding environment and situation.

Unsuitable Extinguishing Media

No restrictions on extinguishing agents for this substance or mixture.

Special Hazards Arising from the Substance or Mixture

Non-combustible.

Hazardous Combustion Products

Combustion may produce: Hydrogen chloride gas.
Surrounding fire may cause release of hazardous vapors.
Hazardous combustion products: Hydrogen chloride gas, Magnesium oxide.

Special Fire-Fighting Procedures

Use water spray to suppress gas/vapor/mist.
Prevent fire-fighting water from contaminating surface water and groundwater systems.

Special Protective Equipment for Firefighters

In case of fire, wear self-contained breathing apparatus.

Section 6: Accidental Release Measures

Personal Precautions

Advice for non-emergency personnel: Avoid dust inhalation. Evacuate the danger area, follow emergency procedures, and consult a professional.
Advice for emergency responders: For personal protection, see Section 8.

Environmental Precautions

Do not allow product to enter drains.

Methods for Cleaning Up

Cover drains. Collect, absorb, and pump spilled material.
Follow substance use restrictions (see Sections 7 and 10).
Dry cleanup, and dispose of affected areas as chemical waste. Avoid dust generation.

Section 7: Handling and Storage

Handling

For precautionary measures, see Section 2.2.

Storage

Keep container tightly closed.
Keep dry.
Storage Class: 13, non-combustible solids.
Recommended Storage Temperature: Refer to product label.
Further Information on Storage Stability: Refer to product label.

Section 8: Exposure Controls/Personal Protection

Workplace Control Parameters for Components

Does not contain substances with occupational exposure limits.

Biological Indicators

Does not contain substances with biological indicators.

Engineering Controls

No data available.

Personal Protective Equipment

Respiratory Protection: Required when dust is generated. Recommendations for filter-type respiratory protective devices will be based on standards such as DIN EN 143, DIN 14387, and other standards related to the respiratory protective equipment used.
Recommended Filter Type: Filter type P1.

Maintenance, Cleaning, and Testing of Respiratory Protective Equipment

Company management must maintain, clean, and test respiratory protective equipment according to the manufacturer's instructions and record these measures properly.

Hand Protection

Material: Nitrile rubber.
Solvent Breakthrough Time: 480 minutes.
Glove Thickness: 0.11 mm.
Protection Index: Full contact.
Manufacturer: KCL 741 Dermatril® L.
Material: Nitrile rubber.
Solvent Breakthrough Time: 480 minutes.
Glove Thickness: 0.11 mm.
Protection Index: Splash contact.
Manufacturer: KCL 741 Dermatril® L.
Note: This information is only applicable to Merck products and their specified use in the Safety Data Sheet. When mixing with other substances, dissolving, or in situations not covered by EN 16523-1, contact a CE-certified glove supplier (e.g., German glove supplier KCL, website: www.kcl.de).

Eye Protection

Use eye protection equipment that has been tested and approved according to official standards such as NIOSH (USA) or EN 166 (EU).
Safety glasses.

Hygiene Measures

Change contaminated clothing. Wash hands after using this substance.

Section 9: Physical and Chemical Properties

Appearance: Solid.
Color: Colorless.
Odor: No data available.
Odor Threshold: No data available.
pH Value: No data available.
Melting Point: 116.7 °C.
Boiling Point/Boiling Range: No data available.
Flash Point (Test Method): Not applicable.
Evaporation Rate: No data available.
Flammability (Solid, Gas): This product is not flammable.
Flammability (Liquid): No data available.
Burning Rate: No data available.
Explosion Limit/Upper Flammable Limit: No data available.
Explosion Limit/Lower Flammable Limit: No data available.
Vapor Pressure: No data available.
Vapor Density: No data available.
Relative Density: No data available.
Density: 1.570 g/cm³ (20 °C).
Solubility:

Water Solubility: 468.7 g/l (20 °C). Method: OECD Test Guideline 105. GLP Laboratory: Yes.

Octanol/Water Partition Coefficient: Not applicable for inorganic substances.
Auto-ignition Temperature: Non-flammable.
Decomposition Temperature: No data available.
Dynamic Viscosity: No data available.
Kinematic Viscosity: No data available.
Flow Time: No data available.
Explosive Properties: No data available.
Oxidizing Properties: No.
Molecular Weight: 203.30 g/mol.
Particle Characteristics:

Particle Size: No data available.

Section 10: Stability and Reactivity

Reactivity: No data available.
Stability: The chemical properties of this product are stable under standard atmospheric conditions (room temperature).
Possibility of Hazardous Reactions: No applicable data.
Conditions to Avoid: No applicable data.
Incompatible Materials: No applicable data.
Hazardous Decomposition Products: See Section 5 Fire-Fighting Measures in case of fire.

Section 11: Toxicological Information

11.1 Toxicological Information

Acute Toxicity:

LD50 Oral - Rat - Female - > 5,000 mg/kg (OECD Test Guideline 423). Remarks: (Anhydrous substance). This value is given based on the substance: magnesium chloride. Symptoms: Mild mucosal irritation.
LD50 Dermal - Rat - Male and Female - > 2,000 mg/kg (OECD Test Guideline 402). Remarks: (Anhydrous substance). This value is given based on the substance: magnesium chloride.

Skin Corrosion/Irritation:

Skin - In Vitro Study: Result: No skin irritation - 15 minutes. (EU Regulation (EC) No 440/2008, Annex B.46). Remarks: (Anhydrous substance). This value is given based on the substance: magnesium chloride. This value is given based on the substance: Magnesium chloride hexahydrate.

Serious Eye Damage/Irritation:

Eyes - Rabbit: Result: No eye irritation - 72h. (OECD Test Guideline 405). Remarks: (Anhydrous substance). This value is given based on the substance: magnesium chloride.

Respiratory or Skin Sensitization:

Maximization Test - Guinea Pig: Result: Negative. (OECD Test Guideline 406). Remarks: (Anhydrous substance). This value is given based on the substance: magnesium chloride.

Germ Cell Mutagenicity:

Test System: Lymphocytes of humans. Metabolic Activation: With or without metabolic activation. Method: OECD Test Guideline 473. Result: Negative. Remarks: (Anhydrous substance). This value is given based on the substance: magnesium chloride. Test System: Mammalian cell gene mutation test.
Test System: Mouse lymphocytes. Metabolic Activation: With or without metabolic activation. Method: OECD Test Guideline 476. Result: Negative. Remarks: (Anhydrous substance). This value is given based on the substance: magnesium chloride.

Carcinogenicity: No data available.
Reproductive Toxicity: No data available.
Specific Target Organ Toxicity - Single Exposure: No data available.
Specific Target Organ Toxicity - Repeated Exposure: No data available.
Aspiration Hazard: No data available.

11.2 Additional Information

Repeated Dose Toxicity - Rat - Male and Female - Oral - 54d - No Observed Adverse Effect Level - > 1,000 mg/kg Remarks: Subacute toxicity. (Anhydrous substance). This value is given based on the substance: magnesium chloride.
To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.
After large intake:

Large inhalation may cause metal fume fever.
Nausea
Vomiting
Diarrhea
Systemic Effects: Decreased blood pressure, Arrhythmia, Muscle weakness, Paralysis symptoms, Fatigue.
After large intake: Cardiovascular dysfunction.

However, there is no hazard when this product is used correctly.
Operate according to industrial hygiene and safety practices.

Section 12: Ecological Information

Ecotoxicity: No data available.
Persistence and Degradability: No data available.
Bioaccumulative Potential: No data available.
Mobility in Soil: No data available.
Other Adverse Effects: No data available.

Section 13: Disposal Considerations

Disposal Methods

Waste Residues: Disposal of waste must comply with national and local regulations. Please keep chemical waste in its original container and do not mix with other waste. Dispose of contaminated containers in the same manner as the product.

Section 14: Transport Information

International Regulations

Air Transport (IATA-DGR): Not applicable.
UN/ID Number: Not applicable.
UN Shipping Name: Not applicable.
Transport Hazard Class: Not applicable.
Subsidiary Risk: Not applicable.
Packing Group: Not applicable.
Labeling: Not applicable.
Packaging Instructions (Cargo Aircraft): Not applicable.
Packaging Instructions (Passenger Aircraft): Not applicable.
Sea Transport (IMDG-Code):

UN Number: Not applicable.
UN Shipping Name: Not applicable.
Transport Hazard Class: Not applicable.
Subsidiary Risk: Not applicable.
Packing Group: Not applicable.
Labeling: Not applicable.
EmS Number: Not applicable.
Marine Pollutant (Yes/No): No.

According to MARPOL 73/78 Annex II and IBC Code: Not applicable to the product supplied.

Special Transport Precautions and Information

Remarks: According to transport regulations, it is not classified as a dangerous good.

Section 15: Regulatory Information

Applicable Regulations

Occupational Safety and Health Act: Applicable.
Occupational Safety and Health Facility Rules: Applicable.
Waste Disposal Act: Not a hazardous or toxic substance.
Standards for Storage, Cleaning, and Disposal of Industrial Waste: Not applicable.
Hazardous Chemical Labeling and Communication Regulations: Not applicable.
Hazardous Chemical Assessment and Classification Management: Not applicable.
Road Traffic Safety Rules: Not applicable.
Permissible Exposure Limits for Workplaces: Does not contain substances with occupational exposure limits.
Organic Solvent Poisoning Prevention Rules: Not applicable.
Specific Chemical Substance Hazard Prevention Standards: Not applicable.
Public Hazardous Materials and Flammable Compressed Gas Manufacturing, Storage, and Handling Site Standards and Safety Management Regulations: Not applicable.
Toxic and Concerned Chemical Substances Control Act:

Toxic Chemical Substances: Not applicable.
Concerned Chemical Substances: Not applicable.
Designation and Operation Management of Priority Management Chemicals: Not applicable.

Section 16: Other Information

Further Information

References: For information on references, please refer to each section.
The information in this document is based on our current knowledge and is intended to provide guidance on appropriate safety precautions for this product. This information does not represent a guarantee of all properties of the product. Users should independently assess its suitability for their intended use, and it does not constitute Merck's warranty of any property of the product.

Prepared By / Prepared By Whom

Name: Merck KGaA LS-QH Department
Address/Phone: 64271 Darmstadt Germany/+49 6151 72-0

Date of Preparation

2025.07.22

Other Information

The above information is considered correct, but does not contain all information and is intended for guidance only. The information in this document is based on our current knowledge and is intended to provide guidance on appropriate safety precautions for this product. This information does not represent a guarantee of all properties of the product. Sigma-

Aldrich and its affiliates shall not be liable for any damages arising from any operation or exposure to the above products. For more terms of use, please refer to the back of the invoice or packaging slip. For more sales terms and conditions, please see www.sigma-aldrich.com or the back of the ticket or packing slip.

Copyright: 2020 Sigma-Aldrich Co. LLC. Company. Permission to copy this document without restriction is granted for internal use only.

Date Format

Year/Month/Day

Full Text of Other Abbreviations

AIIC - Australian Inventory of Industrial Chemicals; ANTT - Brazilian National Land Transport Agency; ASTM - American Society for Testing and Materials; bw - body weight; CMR - Carcinogenic, Mutagenic or Reprotoxic substance; DIN - German Institute for Standardization; DSL - Domestic Substances List (Canada); ECx - Concentration of the test substance causing x% effect; ELx - Load causing x% effect; EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration of the test substance causing x% growth rate reduction; ERG - Emergency Response Guidebook; GHS - Globally Harmonized System of Classification and Labelling of Chemicals; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA - International Air Transport Association; IBC - International Bulk Chemical Code; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO - International Organization for Standardization; KECI - Korean Existing Chemicals Inventory; LC50 - Lethal Concentration 50%; LD50 - Lethal Dose 50%; MARPOL - International Convention for the Prevention of Pollution from Ships; MERCOSUR - Southern Common Market - Agreement on the Transport of Dangerous Goods; n.o.s. - not otherwise specified; Nch - Chilean Chemical Inventory; NO(A)EC - No Observed Adverse Effect Concentration; NO(A)EL - No Observed Adverse Effect Level; NOELR - No Observed Effect Level Rate; NOM - Mexican Official Standard; NTP - National Toxicology Program; NZIoC - New Zealand Inventory of Chemicals; OECD - Organisation for Economic Co-operation and Development; OPPTS - Office of Prevention, Pesticides and Toxic Substances; PBT - Persistent, Bioaccumulative and Toxic chemical; PICCS - Philippine Inventory of Chemicals and Chemical Substances; (Q)SAR - Quantitative Structure-Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; SADT - Self-Accelerating Decomposition Temperature; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TDG - Transport of Dangerous Goods; TECI - Thai Existing Chemicals Inventory; TSCA - Toxic Substances Control Act (USA); UN - United Nations; UNRTDG - United Nations Recommendations on the Transport of Dangerous Goods - Model Regulations; vPvB - very Persistent and very Bioaccumulative chemical; WHMIS - Workplace Hazardous Materials Information System.

The trademarks in the header and/or footer of this document may temporarily not match the purchased product as we transition our brands. However, all information about the product in this document remains unchanged and consistent with the ordered product. For details, please contact: mlsbranding@sial.com

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