Novo Nordisk R&D Investor Event

Chicago, 22 June 2025

Novo Nordisk: A Focused Healthcare Company

This presentation provides an overview of Novo Nordisk's research and development efforts, with a particular emphasis on advancements in diabetes and obesity care. The event features insights from key leaders within the company.

Agenda Highlights

  • Introduction
  • Diabetes: Semaglutide outcome trials, comorbidity data, and ADA guidelines
  • Obesity: Injectable and oral semaglutide, Amylin biology, cagrilintide, CagriSema, Amycretin, and pipeline assets
  • Q&A

Strategic Emphasis

Novo Nordisk's current strategy prioritizes innovation and therapeutic focus within diabetes and obesity care. Key objectives include advancing diabetes treatments, developing superior obesity solutions, strengthening the rare disease pipeline, and establishing a presence in cardiovascular and emerging therapy areas. The company also aims for solid sales growth, operational efficiencies, and attractive capital allocation.

Key Findings and Trials

The presentation details significant clinical trial outcomes, including:

  • The FLOW trial demonstrating semaglutide's reduction in kidney endpoint risk.
  • The SOUL trial showing oral semaglutide's reduction in the risk of major adverse cardiovascular events (MACE).
  • The STRIDE trial indicating semaglutide's improvement in walking distance for people with type 2 diabetes and peripheral artery disease.

Semaglutide is highlighted as addressing multiple treatment goals in the updated 2025 ADA guidelines for type 2 diabetes, serving as a first-line treatment for cardiovascular and kidney risk reduction, glycemic management, and weight management.

Important Drug Information

Victoza® and Ozempic® are approved for people with type 2 diabetes only. Saxenda® and Wegovy® are approved for people with overweight and obesity only.

Forward-Looking Statements

The document includes forward-looking statements based on current plans and expectations. Novo Nordisk cautions that actual results may differ materially due to various risks and uncertainties, including economic conditions, project delays, patent expirations, supply chain disruptions, and regulatory changes. For a detailed overview of risks, refer to the 'Risks' section of the Novo Nordisk Annual Report 2024.

Today's Speakers

  • Karsten Munk Knudsen, Executive Vice President and CFO
  • Martin Holst Lange, Executive Vice President and Head of Development
  • Ludovic Helfgott, Executive Vice President and Head of Product and Portfolio Strategy

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