Safety Data Sheet

SECTION 1: Identification of the substance/mixture and of the company/undertaking

1.1 Product identifiers

Product Name: Anti-MPRIP (rabbit polyclonal)

Product Number: ABN408

Catalog Number: 622253

Brand: Millipore

REACH Number: The product is a mixture. See section 3 for REACH registration number.

1.2 Relevant identified uses of the substance or mixture and uses advised against

Identified uses: Reagent for research and development.

Uses advised against: Not specified.

1.3 Details of the supplier of the safety data sheet

Company: BIOTECHA Eesti OÜ

Address: Liimi 1, 10621 TALLINN, ESTONIA

Email: TechnicalService@merckgroup.com

1.4 Emergency telephone number

Emergency phone number: 16662 (Poison Information Centre), +372 668 1294 (CHEMTREC)

Please contact your local Merck representative for assistance.

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Classification (CLP Regulation (EC) No 1272/2008): According to Regulation (EU) No 1272/2008, this substance is not classified as hazardous.

2.2 Label elements

Labelling (CLP Regulation (EC) No 1272/2008): According to Regulation (EU) No 1272/2008, this substance is not classified as hazardous.

2.3 Other hazards

The substance/mixture does not contain components which are considered persistent, bioaccumulative and toxic (PBT) or very persistent and very bioaccumulative (vPvB) at a concentration of 0.1% or more.

Ecological information: The substance/mixture does not contain components which are considered to have endocrine-disrupting properties that affect the environment according to Article 57 of REACH, Commission Regulation (EU) 2017/2100 or Commission Delegated Regulation (EU) 2018/605, at a concentration of 0.1% or more.

Toxicological information: The substance/mixture does not contain components which are considered to have endocrine-disrupting properties that affect the environment according to Article 57 of REACH, Commission Regulation (EU) 2017/2100 or Commission Delegated Regulation (EU) 2018/605, at a concentration of 0.1% or more.

SECTION 3: Composition/information on ingredients

3.2 Mixtures

Components: No hazardous ingredients.

Remarks: No hazardous ingredients.

SECTION 4: First aid measures

4.1 Description of first aid measures

Inhalation: Move to fresh air.

Skin contact: Take off contaminated clothing immediately. Rinse skin with water/shower. Rinse skin with plenty of water/take a shower.

Eye contact: Rinse eyes thoroughly with plenty of water. Remove contact lenses.

Ingestion: Give water to drink (up to two glasses). Consult a doctor if you feel unwell.

4.2 Most important symptoms and effects, both acute and delayed

The most important symptoms and effects are described in the labelling (see section 2.2) or section 11.

4.3 Indication of any immediate medical attention and special treatment needed

No data available.

SECTION 5: Firefighting measures

5.1 Extinguishing media

Suitable extinguishing media: Use extinguishing methods that are suitable for the surrounding environment and do not harm the local population or the environment.

Unsuitable extinguishing media: No restrictions are given for the extinguishing media for this substance/mixture.

5.2 Special hazards arising from the substance or mixture

Hazards from the substance/mixture during fire: Non-flammable.

Product hazardousness upon combustion: Surrounding fire may release hazardous fumes. Unknown decomposition products.

5.3 Advice for firefighters

Special protective equipment for firefighters: Use self-contained breathing apparatus.

Further information: Avoid contamination of surface water and groundwater with extinguishing water.

SECTION 6: Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Personal precautions: Advice for non-emergency personnel. Avoid breathing vapour and aerosol. Evacuate the danger zone, follow emergency procedures, consult an expert.

Protective equipment: See Section 8.

Emergency procedures: See Section 8.

6.2 Environmental precautions

Environmental precautions: Do not pour the product into drains.

6.3 Methods and material for containment and cleaning up

Containment methods: Cover drains. Collect the spilled substance, bind and pump it away. Observe possible material restrictions (see sections 7 and 10).

Cleaning methods: Collect and remove with a liquid absorbent (e.g. Chemizorb®). Dispose of properly. Clean the contaminated area.

6.4 Reference to other sections

For disposal instructions, see section 13.

SECTION 7: Handling and storage

7.1 Precautions for safe handling

Hygiene measures: Remove contaminated clothing. Wash hands after working with the substance.

Precautions: Precautions are listed in section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Information on storage conditions: Tightly closed.

German storage class (TRGS 510): 12, non-flammable liquids.

Further information: Recommended storage temperature, see product label.

7.3 Specific end use(s)

Some uses are listed in section 1.2; other specific uses are not defined.

SECTION 8: Exposure controls/personal protection

8.1 Control parameters

Occupational exposure limits: Does not contain substances with established occupational exposure limits.

8.2 Exposure controls

Personal protective equipment:

Eye/face protection: Use eye protection that is tested and approved according to EN 166(EU). Safety glasses.

Skin protection:

Hand protection: Not required.

Remarks: Not required.

Respiratory protection: Not provided for, except in case of aerosol formation.

Environmental exposure controls: Do not pour the product into drains.

SECTION 9: Physical and chemical properties

9.1 Information on basic physical and chemical properties

Physical state: Liquid

Colour: Clear

Odour: Data not available

Melting point: Data not available

Boiling point: Data not available

Flash point: Product is not flammable.

Evaporation rate: Not applicable

Flammability (solid, gas): Not applicable

Upper/lower flammability or explosive limits: Not applicable

Vapour pressure: Data not available

Vapour density: Data not available

Relative density: Data not available

Density: Data not available

Solubility(ies):

Water solubility: Soluble (20 °C)

Partition coefficient: n-octanol/water: Data not available

Auto-ignition temperature: Not applicable

Decomposition temperature: Data not available

Viscosity, dynamic: Data not available

Viscosity, kinematic: Data not available

Explosive properties: Not classified as an explosive substance.

Oxidising properties: None

9.2 Other information

Explosives: Not classified as an explosive substance.

Oxidising properties: None

Flammability rate: Data not available

Self-ignition: Not applicable

Evaporation rate: Data not available

SECTION 10: Stability and reactivity

10.1 Reactivity

Data not available

10.2 Chemical stability

The product is chemically stable under standard ambient conditions (room temperature).

10.3 Possibility of hazardous reactions

Hazardous reactions: Possible vigorous reaction with the following: Water partners of known reactivity.

10.4 Conditions to avoid

Conditions to avoid: Information not available.

10.5 Incompatible materials

Data not available

10.6 Hazardous decomposition products

In case of fire: see section 5.

SECTION 11: Toxicological information

11.1 Information on toxicological effects

Mixture:

Acute toxicity:

Oral: Estimated acute oral toxicity > 2,000 mg/kg (Calculation method)

Inhalation: Estimated acute inhalation toxicity 4 h - > 5 mg/l - dust/mist (Calculation method)

Dermal: Estimated acute dermal toxicity > 2,000 mg/kg (Calculation method)

Skin corrosion/irritation: Data not available

Serious eye damage/irritation: Data not available

Respiratory or skin sensitisation: Data not available

Germ cell mutagenicity: Data not available

Carcinogenicity: Data not available

Reproductive toxicity: Data not available

STOT-single exposure: Data not available

STOT-repeated exposure: Data not available

Aspiration hazard: Data not available

11.2 Further information

Endocrine-disrupting properties:

Product: The substance/mixture does not contain components which are considered to have endocrine-disrupting properties that affect the environment according to Article 57 of REACH, Commission Regulation (EU) 2017/2100 or Commission Delegated Regulation (EU) 2018/605, at a concentration of 0.1% or more.

Hazardous properties cannot be excluded, but are unlikely when the product is handled correctly.

SECTION 12: Ecological information

12.1 Toxicity

Data not available

12.2 Persistence and degradability

Data not available

12.3 Bioaccumulative potential

Data not available

12.4 Mobility in soil

Data not available

12.5 PBT and vPvB assessment

Product: The substance/mixture does not contain components which are considered persistent, bioaccumulative and toxic (PBT) or very persistent and very bioaccumulative (vPvB) at a concentration of 0.1% or more.

12.6 Endocrine-disrupting properties

Product: The substance/mixture does not contain components which are considered to have endocrine-disrupting properties that affect the environment according to Article 57 of REACH, Commission Regulation (EU) 2017/2100 or Commission Delegated Regulation (EU) 2018/605, at a concentration of 0.1% or more.

SECTION 13: Disposal considerations

13.1 Waste treatment methods

Product: Waste must be disposed of in accordance with national and local regulations. Keep chemicals in their original containers. Keep separate from other waste. Treat uncleaned containers as the product itself. Directive 2008/98/EC on waste for your information.

SECTION 14: Transport information

14.1 UN number or ID number

ADR: Not classified as dangerous goods.

IMDG: Not classified as dangerous goods.

IATA_P: Not classified as dangerous goods.

14.2 UN proper shipping name

ADR: Not classified as dangerous goods.

IMDG: Not classified as dangerous goods.

IATA_P: Not classified as dangerous goods.

14.3 Transport hazard class(es)

ADR: Not classified as dangerous goods.

IMDG: Not classified as dangerous goods.

IATA_P: Not classified as dangerous goods.

14.4 Packing group

ADR: Not classified as dangerous goods.

IMDG: Not classified as dangerous goods.

IATA_P: Not classified as dangerous goods.

14.5 Environmental hazards

Not classified as dangerous goods.

14.6 Special precautions for user

Remarks: Not classified as a dangerous substance according to transport regulations.

14.7 Transport in bulk according to Annex II of MARPOL and the IBC Code

Not applicable to the product supplied.

SECTION 15: Regulatory information

15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture

REACH - Restriction of manufacture, placing on the market and use of certain dangerous substances, mixtures and articles (Annex XVII): Not applicable

REACH - Candidate List of Substances of Very High Concern for Authorisation (Article 59): Not applicable

Regulation (EC) No 2024/590 on substances that deplete the ozone layer: Not applicable

Regulation (EU) 2019/1021 on persistent organic pollutants (recast): Not applicable

REACH - List of Substances subject to Authorisation (Annex XIV): Not applicable

Seveso III: Directive 2012/18/EU of the European Parliament and of the Council on the control of major-accident hazards involving dangerous substances, and amending and repealing Council Directive 96/82/EEC: Not applicable

SECTION 16: Other information

16.1 Indication of changes

No changes made.

16.2 Abbreviations and acronyms

ADN: European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways; ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road; AIIC: Australian Inventory of Industrial Chemicals; ASTM: American Society for Testing and Materials; bw: body weight; CLP: Regulation (EC) No 1272/2008 on classification, labelling and packaging of substances and mixtures; CMR: Carcinogenic, Mutagenic or toxic to Reproduction; DIN: German Institute for Standardisation; DSL: Domestic Substances List (Canada); ECHA: European Chemicals Agency; EC-Number: European Community number; ECx: Concentration of a substance that causes an x% response; ELx: Loading rate that causes an x% response; EmS: Emergency Schedule; ENCS: Existing and New Chemical Substances (Japan); ErCx: Concentration of a substance that causes an x% increase in growth rate; GHS: Globally Harmonized System of Classification and Labelling of Chemicals; GLP: Good Laboratory Practice; IARC: International Agency for Research on Cancer; IATA: International Air Transport Association; IBC: International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50: Median inhibitory concentration; ICAO: International Civil Aviation Organization; IECSC: Inventory of Existing Chemical Substances in China; IMDG: International Maritime Dangerous Goods Code; IMO: International Maritime Organization; ISHL: Industrial Safety and Health Law (Japan); ISO: International Organization for Standardization; KECI: Korean Existing Chemicals Inventory; LC50: Lethal concentration, 50 percent; LD50: Lethal dose, 50 percent; MARPOL: International Convention for the Prevention of Pollution from Ships; n.o.s.: not otherwise specified; NO(A)EC: Effect concentration, no observed (adverse) effect; NO(A)EL: Effect level, no observed (adverse) effect; NOELR: No observed effect loading rate; NZIoC: New Zealand Inventory of Chemicals; OECD: Organisation for Economic Co-operation and Development; OPPTS: Office of Pollution Prevention and Toxics; PBT: Persistent, Bioaccumulative and Toxic substance; PICCS: Philippine Inventory of Chemicals and Chemical Substances; (Q)SAR: (Quantitative) Structure-Activity Relationship; REACH: Regulation (EC) No 1907/2006 concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RID: Regulations concerning the International Carriage of Dangerous Goods by Rail; SADT: Self-Accelerating Decomposition Temperature; SDS: Safety Data Sheet; SVHC: Substance of Very High Concern; TCSI: Taiwan Chemical Substance Inventory; TECI: Taiwan Existing Chemicals Inventory; TRGS: Technical Rules for Hazardous Substances; TSCA: Toxic Substances Control Act (USA); UN: United Nations; vPvB: very Persistent and very Bioaccumulative substance.

16.3 Key literature references and sources for data

The information provided is believed to be correct, but does not purport to be all-inclusive and should be used as a guide only. Sigma-Aldrich Co., shall not be held liable for any damage resulting from the handling or contact with the above product. For further terms and conditions please see the reverse side of the invoice or packing slip.

Copyright 2020 Sigma-Aldrich Co. LLC. License is granted to make unlimited paper copies for internal use only.

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