Zebra ZD421 Direct Thermal Desktop Printer

Quick Start Guide

1. Setup

IMPORTANT: Go to zebra.com/zd421d-info and install the driver for your printer. The driver MUST be installed before connecting the printer to the computer, or it will cause complications. If your Microsoft Windows-based computer does not have the driver installed for this printer, download it from zebra.com/zd421d-info and install it before continuing.

2. Remove Packing

After unpacking, make sure you have all items shown below:

Media not included.

3. Remove Packing (continued)

  1. Open the printer and remove the packing material.

4. Load Media

  1. Slide the release latches (1) to the front to unlock the cover.
  2. Unroll (1) and discard (2) the outer layer of the media roll (3).
  3. Spread the roll holders open (1) and place the roll (2) into the printer.
  4. Verify the roll spins easily on the holder.

5. Load Media (continued)

  1. Pull the end of the roll past the front edge of the printer.
  2. Press the media under the guides (1).
  3. Align the sensor to the center of the roll for regular labels (1).
  4. Align the sensor to the edge of the roll for marked labels (1).

6. Adjust Sensor

(This section visually demonstrates sensor alignment for different label types, as described in step 5.)

7. Close Printer

  1. Push down on the front edge of the printer until it locks.

8. Connect Power

  1. Plug the power supply into the printer.
  2. Plug the power cable into the power supply.
  3. Plug the power cord into an appropriate receptacle.
  4. Verify that the power supply lights green.

9. Connect USB

  1. Connect a USB cable to the printer.
  2. Connect the other end to your computer.

10. Power On

  1. Press POWER (1).

When the printer is ready, the printer status light turns green (1).

11. Power On (continued)

(This section reiterates the power-on status light.)

12. Smart Calibration

(This section visually demonstrates the smart calibration process.)

Press and hold PAUSE (1) + CANCEL (2) for two seconds to line up the labels.

13. Print Configuration

(This section visually demonstrates printing a configuration report.)

Press and hold FEED (1) + CANCEL (2) for two seconds to print a configuration report.

Support and Information

For user documentation, visit zebra.com/zd421d-info.

For quick answers and knowledge base, visit zebra.com/knowledge.

For label design, visit zebra.com/zebradesigner.

To join the Zebra user community, visit zebra.com/supportcommunity.

To learn about genuine Zebra supplies, visit zebra.com/supplies.

To contact Zebra about your printer, visit zebra.com/contactsupport.

To manage your printer, visit zebra.com/profilemanager.

To secure your printer, visit zebra.com/printsecure.

For product patent information, visit ip.zebra.com.

Media Out

When the media runs out, the printer status and media status lights will turn red (1).

  1. Open the printer and discard the empty roll (1).

Cleaning

  1. Clean the printhead (1) with a cleaning pen (2). Clean from the middle to the outside. Do not use a cleaning pen on the platen.
Models: ZD421, ZD421D, ZD421 Desktop Printer, ZD421, Desktop Printer, Printer

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