product overview for Hamilton models including: Microlab NIMBUS, Hamilton, Automated Liquid Handler, Pipetting Workstation, NIMBUS384, NIMBUS96, NIMBUS4, laboratory automation, liquid handling, CO-RE, air displacement pipetting

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Microlab® NIMBUS
Personal Pipetting Workstation

MICROLAB NIMBUS
Microlab NIMBUS
The Microlab NIMBUS is a compact, multi-channel automated liquid handler, offering speed, flexibility, ease-of-use and superior pipetting performance...at a surprisingly affordable price. NIMBUS comes available in three highly configurable open or enclosed platforms:
XXNIMBUS384: 384-channel multi-pipetting head XXNIMBUS96: 96-channel multi-pipetting head (MPH) XXNIMBUS4: 1 ­ 4 independent liquid
channels

Who uses the Microlab NIMBUS?
NIMBUS is a small-scale liquid handler designed for space and budget-conscious labs that require
XXhigh pipetting accuracy and precision
XXlow/medium throughput XXsm all footprint XXaffordability
Where is Microlab NIMBUS used?
Common industries utilizing NIMBUS include: XXDrug Discovery XXBasic & Applied Research XXBiotechnology XXDNA Forensics XXClinical Diagnostics XXEnvironmental Analysis XXAnd many others...

Microlab NIMBUS ENCLOSED Extended Enclosed
What is a Personal Pipetting Workstation?
In today's laboratory, automation of some workflows is better served by taking a `divide and conquer' approach.
In contrast to large, multi-integrated, high-end systems designed for automating complex workflows, NIMBUS is a small-footprint, leanintegrated, entry-level pipettor ideally suited for automating a single or select set of liquid handling routines. A flexible deck layout and a broad range of modular accessories and options makes reconfiguration for new applications quick and easy. What's more, an attractive price point makes NIMBUS very affordable, allowing even budget-challenged facilities to place multiple systems into a single laboratory.

MICROLAB NIMBUS

Why choose Microlab NIMBUS?

Integrated options, intuitive software and the backing of Hamilton's renowned service and applications support makes the NIMBUS an indispensable tool for budget and spaceconstrained labs. Using proven air displacement pipetting, NIMBUS offers the same liquid handling performance as higher end systems, yet at a fraction of the price.

Imagine Convenience...

Microlab NIMBUS96

Microlab NIMBUS4

Some of the applications the Microlab NIMBUS can perform

DNA/RNA extraction and purification PCR setup and purification
Post-PCR cleanup
Sequencing assays

Microarray sample preparation
Cloning assays Protein purification & digestion MALDI target spotting

Cell assays & feeding
ADMET assays Solubility assays Compound handling

Sample normalization CE analysis setup

Solid phase extraction

Magnetic separation
Liquid-liquid extraction
ELISA preparation & processing Sample pooling Genomics, Proteomics & Cellomics assays

3

MICROLAB NIMBUS Family
Meet the Microlab NIMBUS Family
NIMBUS Extended Enclosed NIMBUS Standard Enclosed
NIMBUS4

MICROLAB NIMBUS Family
NIMBUS Large Extended Enclosed: for large third-party integration
NIMBUS96
5

MICROLAB NIMBUS enclosed
Microlab NIMBUS Enclosed
The newest member of the Hamilton Robotics family, the Microlab NIMBUS Enclosed, is a high-speed platform with enhanced processing security. The instrument features a 50 µL 384-channel MPH, 1 mL 96-channel MPH for fast platebased pipetting or up to 4 independent liquid channels for flexible pipetting to and from tubes and plates. NIMBUS Enclosed uses air-displacement pipetting technology for the highest precision and accuracy, and features a locking cover set that minimizes environmental contamination.
Labware Gripper Arm
An optional labware gripper enables easy handling of single or stacked microplates, deep-well plates, lids, and Hamilton's Nestable Tip Racks (NTRs). The systems extended reach and 270 degrees of rotation allow for seamless handoffs to integrated devices located on- and off-deck.
Extension Plate (Extended Enclosed only)
A plate located on the left-hand side of the NIMBUS Extended Enclosed allows for 4 additional non-pipetable locations. The locations can use Hamilton stackers, pedestals, Hamilton Heater Shaker, and additional small third-party devices.
Door Locks
Doors automatically lock when the system is running
Vibrating Waste Station
(Not available on all system configurations) Worry free waste management removes tips and empty tip racks by gently vibrating them out of the system.
Movement Indicator
Provides at-a-glance cues regarding the movement status of NIMBUS, even from across the room.

CO-RE Paddles
Using two pipetting channels in parallel, NIMBUS can transport plates or tips across the deck without the need for a dedicated labware gripper. CO-RE Paddles are available in both 1 mL and 5 mL channel versions.

MICROLAB NIMBUS enclosed
4 x Independent CO-RE Air Displacement Channels
Flexible channels are available in 1000 µL or 5000 µL, enabling independent movement in both Y and Z axes, and an unprecedented pipetting range of 0.5 µL to 5000 µL Each channel features Capacitance Liquid Level Detection (cLLD) and Pressure-Based Liquid Level Detection (pLLD) to handle both polar and non-polar (organic) fluids.
CO-RE® II 96 MPH
A high-speed 96-channel head ensures fast and accurate pipetting to 96- or 384-well plates across a wide range of volumes, from 1 µL to 1000 µL. CO-RE II also features Capacitance-Based Liquid Level Detection (cLLD).
CO-RE® II 384 MPH
A highly precise, time saving 384 head, which accurately & precisely pipettes to 96, 384 and 1536 plates, in individual, column, row and whole plate formats. A volume range of 0.5 µL to 50 µL with standard feature Capacitance-Based Liquid Level Detection.
Communications & Control Panel
Simply connect the ethernet cable from your PC to the communications port, plug in the power cable and push the power button to bring NIMBUS to life. An Auxiliary Communications Panel is also featured to support integrated peripheral devices.

Main Deck
The enclosed platform allows for easy loading of pedestals, adapters, plates, tubes, and tip racks onto the high-density main deck. Choose from 3 different deck styles:
XX9+ 2 ­ 9 main deck positions and 2 subdeck positions XX3x4 ­ 12 main deck positions XXShift-n-Scan ­ 8 main deck positions and integrated tube barcode scanner (NIMBUS4 only)

7

MICROLAB NIMBUS96/384
Microlab NIMBUS96/384
The Microlab NIMBUS96/384 represents the latest in compact, high speed automated liquid handling. Using air-displacement pipetting technology for the highest precision and accuracy.
Labware Gripper Arm
An optional labware gripper makes for easy handling of single or stacked microplates, deepwell plates, lids and Hamilton's Nestable Tip Racks (NTRs). Extended reach and 270° of rotation allows for seamless handoffs to integrated devices located both on and off-deck.
Pause/Park Buttons
The park button moves the pipetting head out of the way for easier access to the deck during set-up, while the pause button allows for temporary interruption of a method mid-stream.

Small Footprint
NIMBUS' compact size provides for positioning on virtually any bench top as well as in select commercial hoods and bio-safety cabinets.

Waste Station
An attachable waste receptacle (not shown) accommodates used tips and empty NTRs.

Status Indicator
Provides `at-a-glance' cues to the operational status of NIMBUS.

MICROLAB NIMBUS96/384
CO-RE® II 96 MPH
A high-speed 96-channel head ensures fast and accurate pipetting to 96- or 384-well plates across a wide range of volumes, from 1 µL to 1000 µL. CO-RE II also features Capacitance-Based Liquid Level Detection (cLLD).
CO-RE® II 384 MPH
A highly precise, time saving 384 head, which accurately pipettes to 96, 384 and 1536 plates, in individual, column, row and whole plate formats. A volume range of 0.5 µL to 50 µL with standard feature Capacitance-Based Liquid Level Detection.
Communications & Control Panel
Simply connect the ethernet cable from your PC to the comm port, plug in the power cable and push the power button to bring NIMBUS to life. An Auxiliary Communications Panel is also featured to support integrated peripheral devices.

Main Deck
An open platform allows for easy loading of carrier pedestals, adapters, plates, tubes and tip racks onto the high-density main deck. Up to 5 standard microplates can be stacked into a single SBS position. Choice of 2 different deck styles:
XX9+ 2 - 9 main deck positions and 2 subdeck positions XX3x4 - 12 main deck positions

9

MICROLAB NIMBUS4
Microlab NIMBUS4
The Microlab NIMBUS4 is a compact and easy-to-use automated pipetting workstation designed to meet the needs of small-scale projects and low throughput applications. Using airdisplacement pipetting technology, NIMBUS4 offers superior performance and features up to 4 independent liquid channels for flexible pipetting to/from tubes and plates.
Labware Gripper Arm
An optional labware gripper makes for easy handling of single or stacked microplates, deepwell plates, lids and Hamilton's Nestable Tip Racks (NTRs). Extended reach and 270° of rotation allows for seamless handoffs to integrated devices located both on and off-deck.
Pause/Park Buttons
The park button moves the pipetting head out of the way for easier access to the deck during set-up, while the pause button allows for temporary interruption of a method mid-stream.
Small Footprint
NIMBUS' compact size provides for positioning on virtually any bench top as well as in select commercial hoods and bio-safety cabinets.
Waste Station
An attachable waste receptacle (not shown) accommodates used tips and empty NTRs.

Status Indicator
Provides `at-a-glance' cues to the operational status of NIMBUS.

MICROLAB NIMBUS4
4 x Independent CO-RE Liquid Channels
Allowing for independent movement in both Y and Z axes, flexible channels are available in either 1000µL or 5000µL sizes for an unprecedented dynamic pipetting range from 0.5µL to 5000µL. Each channel features cLLD and pressure-based Liquid Level Detection (pLLD) to handle both polar and non-polar (organic) fluids.

Communications & Control Panel
Simply connect the ethernet cable from your PC to the comm port, plug in the power cable and push the power button to bring NIMBUS to life. An Auxiliary Communications Panel is also featured to support integrated peripheral devices.

Main Deck
An open platform allows for easy loading of carrier pedestals, adapters, plates, tubes and tip racks onto the high-density main deck. Up to 8 standard microplates can be stacked into a single position. Choice of 3 different deck styles: XX9+ 2 - 9 main deck positions and 2 subdeck positions XX3x4 - 12 main deck positions (no SubDeck) XXShift-n-Scan ­ 8 main deck positions and integrated tube barcode scanner
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Technology

Technology

Innovative technology for higher process performance and reliability.

Compressed O-Ring Expansion (CO-RE)

Many of today's applications require precision in tip attachment and positioning. To accomplish this, HAMILTON utilizes proprietary Compressed O-Ring Expansion (CORE) technology. CO-RE technology attaches disposable tips using a highly robust lock-and-key style mechanism. This enables a positional precision of + 0.1mm on all axes. The system requires virtually no vertical force for tip attachment or ejection, thus eliminating mechanical stress and minimizing the production of aerosols. Reduced stress also improves overall system reliability and throughput.
Air Displacement Pipetting
NIMBUS utilizes proven air displacement pipetting, similar to high precision handheld electronic pipettors. Benefits of this technology include:
XXReduced risk of contamination or sample dilution (no system fluid)
XXHigh pipetting accuracy and precision from sub-microlitre to large (>1mL) volumes
XXIncreased robustness and easier maintenance owing to lack of system liquids, diluters, valves or complicated tubing

Plunger Air
Tip

Anti-Droplet Control (ADC)
This technology serves to compensate in real time for pressure changes in the liquid channels caused by high vapor pressure of volatile solvents. Upon activation, ADC prevents inadvertent dripping from the channels, reducing the risk of contaminating the deck. (NIMBUS4 only)

Pressure Sleeve O-Ring
Stop

Tip O-Ring Groove
Coupling Shoulder

Liquid Level Detection (LLD)
NIMBUS uses LLD technology to determine liquid levels in tubes and plates located on the pipetting deck. There are two modes of LLD: capacitative LLD (c-LLD), used to detect most types of liquids in most types of vessels; and pressure-based LLD (p-LLD), which can detect virtually all fluid types, including foaming liquids and non-conductive organic solvents. cLLD is available on all Hamilton Robotic Systems, NIMBUS384 (MPH channels A5 & P20), NIMBUS96 (MPH channels A1, B2, G11 & H12) and NIMBUS4 (pLLD is available on NIMBUS4 only). For even greater confidence in LLD, a dual mode LLD approach may be used (NIMBUS4 only).
Monitored Air Displacement (MAD)
By monitoring the air-based pipetting action, NIMBUS can detect clots or empty wells during the aspiration step in real time. It can also be used to pipette highly volatile solvents (NIMBUS4 only).

Technology

Total Aspiration and Dispense Monitoring (TADM)
During crucial sample transfers (e.g. in vitro Diagnostics or DNA Forensics), parameters may be set to monitor, in real time, both the aspiration and dispense steps. TADM verifies with a traceable digital audit trail that a sample has been successfully transferred (NIMBUS4 only).

13

Software
Software

Hamilton's Microlab INSTINCT software provides an intuitive graphical user interface for simplified instrument control and streamlined method programming, allowing you to achieve results faster and with less training than ever before. Hamilton recognizes the critical role that instrument control software plays in overall system usability and end-user satisfaction.
INSTINCT Software
INSTINCT features several tools to enhance the end-user experience:
XXLabware Library ­ a comprehensive menu of commercially available microplates, deep well plates, reagent troughs/tubs as well as the complete line of Hamilton's CO-RE disposable tips
XXFa vorites Tool - enables quick selection of your most commonly-used labware XXLiquid Class Tuner ­ an easy to use utility for selecting optimal pipetting parameters and improved liquid handling performance XX3-D Viewing ­ an intuitive tool for visualizing deck layouts

SMART PIPETTING
Combining these preferences together with other user-defined input (e.g. pipetting volume), INSTINCT's built-in intelligence provides:
XXAutomated deck layouts ­ auto-populates the pipetting deck with carriers, microplates/tubes and tips, making setup of deck layouts a snap
XXAutomated tip tracking ­ tracks tip usage, location and status of tip racks XXSmart plate movements ­ auto-transporting of labware to destination or waste locations

Basic Tasks
For basic tasks, INSTINCT software features a series of dedicated Wizards available for commonly performed pipetting routines, each guiding you step-by-step towards final method creation.
XXSerial Dilutions XXReagent Additions XXPlate Replications XXTu be to Plate XXPCR set-up XXSPE XXAnd many more...

ADVANCED PROGRAMMING
For the most sophisticated methods, powerful VENUS software is also featured as standard, providing the flexibility to create or modify a complex method from scratch, ensuring that your requirements are never compromised. VENUS also features a range of utilities for:
XXWorklist importing/exporting XXError handling and recovery XXLIMS adaptation XXDatabase/server controls XXScheduling XXIntegrated third party device control

Progress Bar
Graphical status of pipetting volumes
Step-wise view of protocol
Plate processing order
21 CFR Part 11 Regulatory Tools
VENUS software contains the software tools required to use NIMBUS in compliance with CFR 21 part 11. The tools provide audit trails, user group defined security functionality and file fidelity with the checksum system.

Software
Connection Status Indicator
Graphical display of dispense patterns
Favorite labware menu
Top-down view of deck layout Undo/Redo function
XXIn tuitive graphical user interface
XXD esigned for users in busy labs from beginner to advanced
15

Integrated Options
Integrated Options
Labware Gripper ARM The NIMBUS Labware Gripper Arm option makes for quick and easy handling of single or stacked microplates, deepwell plates, lids and HAMILTON's Nestable Tip Racks (NTRs). Extended reach and 270° of rotation allows for seamless handoffs to integrated devices located both on and off-deck.
1D bc scanner Reads 1D barcodes microplates presented by Labware Gripper or CO-RE Paddles.
Shift-n-Scan Tube Barcode Scanner (NIMBUS4 only) On-deck module for rapid reading of 1D barcoded tubes; accommodates wide variety of tube sizes; compatible with all major symbologies.

NIMBUS Vacuum Station (NVS)
Fully software-integrated vacuum system with adjustable pressure control; allows automation of SPE and other vacuum based applications.

Integrated options

HAMILTON Heater Shaker 2 (HHS2) Hamilton's latest heater/shaker device offers efficient on-deck orbital shaking and heating (up to 100° C). Accomodates a variety of popular standard and deep well microplates.
Plate Tilt module An integrated module that lifts plates at an angle to remove liquid out of flat bottomed plates.
Fill Module A liquid filling module used for large volumes of liquid needed on the deck. The module comes standard with a Liquid Sensing Sensor and easily replaced tubing.
Plate Readers, Washers and other 3rd party devices A wide variety of 3rd party peripheral devices are also available for integration.
17

Accessories
Labware Handling:
CO-RE Paddles (NIMBUS4 only) CO-RE grippers are a cost-effective means for the on-deck transport of labware. Using two pipetting channels in parallel, NIMBUS4 can transport plates or tips (NTRs only) across the deck without the need for a dedicated Labware Gripper. For transfers to off-deck locations and devices, the Labware Gripper option is required. CO-RE Grippers are available in both 1 mL and 5 mL channel versions.
Labware Pedestals :
NTR Pedestal holds 1 - 4 x Nestable Tip Racks (NTRs); also used for Small Tube Adapters
MTP Pedestal holds 1 x standard SBS microtiter plate
DWP Pedestal holds 1 x standard SBS deep well plate; also used for PCR Tray
FTR Pedestal holds 1 x Framed Tip Rack of CO-RE disposable tips; also used for Filtered CO-RE tips
MTP Labware Gripper & Paddle Stacking Pedestals holds a stack of up to 5 x standard SBS microtiter plates; used with LabWare Gripper only
Reagent Trough Pedestal holds up to 5 x 50 mL reagent troughs
12x75 - 13x100 mm 32 Tube Position Pedestal holds 32 x small sample tubes in one SBS position; accommodates the following tube sizes (diameter x height): XX12 mm x 75 mm; 12 mm x 100 mm; 13 mm x 75 mm; 13 mm x 100 mm Tip Isolator Pedestal available for 50, 300 and 1000 µL tips with an integrated deep well plate. The pedestal prevents cross contamination between re-used tips
1536 Plate Pedestal accomodates most commercially available 1536 MTP plates

Accessories
16x75 - 17x100 mm & 15 mL Falcon Type 24 Tube Position holds 24 x medium sample tubes; accommodates the following tube sizes (diameter x height): XX16 mm x 75 mm; 16 mm x 100 mm; 17 mm x 75 mm; 17 mm x 100 mm
50 mL Falcon Like Tubes 6 Position holds 6 x 50 mL (i.e. Falcon brand) tubes; accommodates the following tube sizes (diameter x height)
Labware Adapters:
96 PCR Tray Adapter accommodates most commercially available skirted, semi-skirted and unskirted 96-well PCR trays
384 PCR Tray Adapter accommodates most commercially available skirted, semi-skirted and unskirted 384-well PCR trays
CO-RE Tip Adapter holds 96 x CO-RE tips; required to access single rows/columns of all Framed CO-RE tips and 10 µL NTR tips Small Tube Adapter holds up to 32 x standard volume (approx 1.7 mL) `Conical' reaction tubes or 1.8 mL cryovials; a slot feature keeps snap caps out of way to allow access for the pipetting channels
Multi-Tube Adapter holds up to 24 x standard volume 1.8 - 2.0 mL conical tubes or 1.8 cryovials and up to (8) 5 mL standard vial
4 Position Adapter holds up to 5 positions on the reagent trough pedestal adding up to 4 positions for 1.8 - 2.0 mL conical tubes or 1.8 cryovials
Consumables:
CO-RE Disposable Tips The use of superior quality tips is essential to maximizing pipetting performance of your automated liquid handling workstation. Hamilton designs and manufactures our own disposable CO-RE tips, ensuring complete control over the production process to yield only the very highest quality product. All CO-RE tips are manufactured under strict tolerances and undergo the most stringent QA inspection process in the industry. Hamilton's CO-RE disposable tips are available in 96 or 384 tip traditional frames as well as spacesaving, stackable 96 tip Nestable Tip Racks (NTRs). CO-RE tips are available in 10, 50, 300, 1000 and 5000 µL volumes, black conductive or clear, filtered or unfiltered, `clean' (nuclease and pyrogen-free) or sterile.
19

Specifications: NIMBUS96/384 Enclosed

NIMBUS96/384 Enclosed Functional & Performance Specifications:

Parameter

Specification

Input Power (Primary) Universal Supply:
Output Power (Secondary) Power: Wattage:
Power supply
Physical Dimensions (1000 µL) | Operating Dimensions Length: Width: Height:

100 - 240 VAC, 50-60 Hz, 5 A
+42 VDC +5% 600 Watts maximum UL/CSA/CE approved universal power supply with IEC connection
53.5 in. (135.9 cm) 27.9 in. (70.9 cm) 35.0 in. max (88.9 cm)

With Large Extended Enclosed Physical Dimensions Length: Width: Height:

65.5 in. (166.1 cm) 27.5 in. (70.9 cm) 35.0 in. max (88.9 cm)

Weight: Weight with Large Extended Enclosed:

223 lbs (101.2 kg) approx. 243 lbs (110.2 kg) approx.

Pipetting specifications for disposable tips - 96 channel CO-RE head

Disposable tip size:

10 µL:

10 µL:

10 µL:

50 µL:

50 µL:

50 µL:

300 µL:

300 µL:

300 µL:

Test environment & equipment available upon request

1000 µL:

Volume
1 µL 5 µL 10 µL 1 µL 5 µL 50 µL 10 µL 100 µL 300 µL 1000 µL

Accuracy |R| (%) 5.0% 2.5% 1.5% 5.0% 2.5% 1.5% 3.0% 1.5% 1.0% 1.0%

Pipetting specifications for disposable tips - 50 L CO-RE 384-Probe Head
Disposable tip size:

Volume

Test environment & equipment available upon request

50 µL: 50 µL: 50 µL: 50 µL: 50 µL: 50 µL: 50 µL: 50 µL: 50 µL:

0.1 µL 0.5 µL 1 µL 1 µL 5 µL 5 µL 10 µL 10 µL 50 µL

Precision CV (%) 8.0% 6.0% 3.5% 15.0% 3.0% 4.0% 2.0% 3.0% 2.0%

Pipetting specifications for disposable tips - Using the 50 L CO-RE 384-Probe Head as a 96-Probe Head
Disposable tip size:

Volume

Test environment & equipment available upon request

300 µL Rocket: 300 µL Rocket: 300 µL Rocket: 300 µL Rocket: 300 µL Rocket:

1 µL 5 µL 10 µL 100 µL 300 µL

Precision CV (%) 4.0% 2.0% 2.0% 2.0% 2.0%

Liquid level detection 96 channel CO-RE head:

Capacitive liquid level detection (cLLD) (Channels A1, B2, G11 and H12)

Liquid level detection 384 channel CO-RE head:

Capacitive liquid level detection (cLLD) (Channels A5 and P20)

Deck Capacity

11 or 12 positions

Communication type

Ethernet

Precision CV (%)
5.0% 2.0% 2.0% 5.0% 2.0% 0.75% 2.0% 2.0% 2.0% 0.75%

Specification: NIMBUS96/384 Enclosed

NIMBUS96/384 Enclosed Functional & Performance Specifications (continued):

Parameter
Operating Temperature: Relative Humidity: Altitude:
Storage Temperature:
CSA Certification Installation category: Pollution degree:

Specification
15o to 35oC (59o to 95oF) 30% to 85% R.H. non-condensing 2000 m (1.2 miles) above sea level
-20oC (-4.0oF) @ 10% humidity to 70oC (158oF) @ 90% humidity non-condensing
II 2

NIMBUS96/384 Enclosed Labware Gripper Specifications:

Parameter
Plate format
Absolute positioning
Gripping force Transport mass Operating Data

Specification

microtiter footprint plate height < 43 mm

accuracy

X, Y, Z = 0.5 mm

reproducibility X, Y, Z = 0.25

5 N ­ 16 N (default 9 N): Labware Gripper Landscape 190220

300g filled deep-well plate

Temperature range Relative humidity Altitude

15°C ­ 35°C 30% ­ 85% (non-condensing, indoors) 2000 m above sea level

NIMBUS96/384 Enclosed Dimensions
with Extended Enclosed Shown

Large Extended Enclosed
Height: 35.0" (88.9 cm) Length: 65.5" (166.4 cm) Width: 27.9" (70.9 cm) Weight: 243 lbs (110.2 kg) approx.
21

Specifications: NIMBUS4 Enclosed

NIMBUS4 Enclosed Functional & Performance Specifications:

Parameter
Input Power (Primary) Universal Supply: Output Power (Secondary) Power: Wattage: Power supply Physical Dimensions / Operating Dimensions Length: Width: Height:
With Extended Enclosed Physical Dimensions Length: Width: Height:
With Large Extended Enclosed Physical Dimensions Length: Width: Height:
Weight: Weight with Extended Enclosed: Weight with Large Extended Enclosed: Pipetting specifications for disposable tips Disposable tip size:
Test environment & equipment available upon request
Liquid level detection Independent Channels:
Deck Capacity Communication type Operating
Temperature: Relative Humidity: Altitude: Storage Temperature:
CSA Certification Installation category: Pollution degree: Plate format

Specification

100 - 240 VAC, 50-60 Hz, 5A
+42 VDC +5% 600 Watts maximum UL/CSA/CE approved universal power supply with IEC connection
41.2 in. (104.6 cm) 27.9 in. (70.9 cm) 32.7 in. max (83.1 cm)

53.5 in. (135.9 cm) 27.9 in. (70.9 cm) 35.0 in. max (88.9 cm)

65.5 in. (166.1 cm) 27.9 in. (70.9 cm) 35.0 in. max (88.9 cm)

203 lbs (92.1 kg) approx. 223 lbs (101.2 kg) approx. 243 lbs (110.2 kg) approx.

Volume

10 µL: 10 µL: 10 µL: 50 µL: 50 µL: 50 µL: 300 µL: 300 µL: 300 µL: 1000 µL: 1000 µL: 1000 µL:

1 µL 5 µL 10 µL 1 µL 5 µL 50 µL 10 µL 50 µL 300 µL 10 µL 100 µL 1000 µL

Accuracy |R| (%)
5.0% 2.5% 1.5% 5.0% 2.5% 1.5% 3.0% 1.5% 1.0% 7.5% 2.0% 1.0%

Precision CV (%)
5.0% 2.0% 1.5% 5.0% 2.0% 1.0% 2.0% 1.0% 1.0% 3.5% 1.0% 1.0%

For pipetting of less than 10 µL HAMILTON recommends 10 µL/50 µL volume disposable tips to achieve highest pipetting precision.

Capacitive liquid level detection (cLLD) (Pressure liquid level detection (pLLD)

8-12 positions

Ethernet

15o to 35oC (59o to 95oF) 30% to 85% R.H. non-condensing 2000 m (1.2 miles) above sea level

-20oC (-4.0oF) @ 10% humidity to 70oC (158oF) @ 90% humidity non-condensing

II 2
microtiter footprint plate height < 43 mm

Specifications: NIMBUS4 Enclosed

NIMBUS4 Enclosed Labware Gripper Specifications:

Parameter
Plate format
Absolute positioning
Gripping force Transport mass Operating Data

Specification

microtiter footprint plate height < 43 mm

accuracy

X, Y, Z = 0.5 mm

reproducibility X, Y, Z = 0.25

5 N ­ 16 N (default 9 N): Independent Channels Gripper Landscape 190220

300g filled deep-well plate

Temperature range Relative humidity Altitude

15°C ­ 35°C 30% ­ 85% (non-condensing, indoors) 2000 m above sea level

NIMBUS4 Enclosed Dimensions
with Standard Extended Enclosed Shown

Standard Extended Enclosed Large Extended Enclosed

Height: 32.7" (83.1 cm) Length: 41.2" (104.6 cm)

Height: 35.0" (88.9 cm) Length: 65.5" (166.3 cm)

Width: 27.9" (70.9 cm) Weight: 203 lbs approx. (92.1 kg)

Width: 27.9" (70.9 cm) Weight: 243 lbs (110.2 kg) approx.

23

Specifications: NIMBUS96

NIMBUS96 Functional & Performance Specifications:

Parameter

Specification

Input Power (Primary) Universal Supply:

100 - 240 VAC, 50-60 Hz, 5 A

Output Power (Secondary) Power: Wattage:

+42 VDC +5% 600 Watts maximum

Power supply

UL/CSA/CE approved universal power supply with IEC connection

Physical Dimensions (1000µL) Length: Width: Height:
Operating Dimensions Width: (FRONT to REAR) Length: (LEFT to RIGHT) Height:
Weight:

37.4 in. (94.9 cm) 20.1 in. (51.1 cm) 30.6 in. max (77.7 cm)
20.1 in. (51.1 cm) 51.8 in. (131.6 cm) 30.6 in. max (77.7 cm)
145 lbs (65.8 kg), 1000µL

Pipetting specifications for disposable tips - 96 channel CO-RE head

Disposable tip size:

10 µL:

10 µL:

10 µL:

50 µL:

50 µL:

50 µL:

300 µL:

300 µL:

300 µL:

Test environment & equipment available upon request

1000 µL:

Volume
1 µL 5 µL 10 µL 1 µL 5 µL 50 µL 10 µL 100 µL 300 µL 1000 µL

Accuracy |R| (%) 5.0% 2.5% 1.5% 5.0% 2.5% 1.5% 3.0% 1.5% 1.0% 1.0%

Precision CV (%)
5.0% 2.0% 2.0% 5.0% 2.0% 0.75% 2.0% 2.0% 2.0% 0.75%

Liquid level detection 96 channel CO-RE head:

Capacitive liquid level detection (cLLD) (Channels A1, B2, G11 and H12)

Deck Capacity

8-12 positions

Communication type

Ethernet

Operating Temperature: Relative Humidity: Altitude:

15o to 35oC (59o to 95oF) 30% to 85% R.H. non-condensing 2000 m (1.2 miles) above sea level

Storage Temperature:

-20oC (-4.0oF) @ 10% humidity to 70oC (158oF) @ 90% humidity non-condensing

CSA Certification

Installation category:

II

Pollution degree:

2

Specification: NIMBUS96

NIMBUS96 Labware Gripper Specifications:

Parameter
Plate format
Absolute positioning
Gripping force Transport mass Operating Data

Specification

microtiter footprint plate height < 43 mm

accuracy

X, Y, Z = 0.5 mm

reproducibility X, Y, Z = 0.25

5 N ­ 16 N (default 9 N): Labware Gripper Landscape 190220

300g filled deep-well plate

Temperature range Relative humidity Altitude

15°C ­ 35°C 30% ­ 85% (non-condensing, indoors) 2000 m above sea level

NIMBUS96 Dimensions

25

Specifications: NIMBUS4

NIMBUS4 Functional & Performance Specifications:

Parameter
Input Power (Primary) Universal Supply: Output Power (Secondary) Power: Wattage: Power supply Physical Dimensions Length: Width: Height: Operating Dimensions Width: (FRONT to REAR) Length: (LEFT to RIGHT) Height: Weight: Pipetting specifications for disposable tips Disposable tip size:
Test environment & equipment available upon request
Liquid level detection Independent Channels:
Throughput Independent Channels:
Deck Capacity Communication type Operating
Temperature: Relative Humidity: Altitude: Storage Temperature:
CSA Certification Installation category: Pollution degree: Plate format

Specification

100 - 240 VAC, 50-60 Hz, 5A
+42 VDC +5% 600 Watts maximum UL/CSA/CE approved universal power supply with IEC connection
37.4 in. (95 cm) 20.1 in. (51.1 cm) 30.3 in. max (77.0 cm)

20.1 in. (51.1 cm) 49.0 in. (124.5 cm) 30.3 in. max (77.0 cm)

145 lbs (65.8 kg)

Volume

10 µL: 10 µL: 10 µL: 50 µL: 50 µL: 50 µL: 300 µL: 300 µL: 300 µL: 1000 µL: 1000 µL: 1000 µL:

1 µL 5 µL 10 µL 1 µL 5 µL 50 µL 10 µL 50 µL 300 µL 10 µL 100 µL 1000 µL

Accuracy |R| (%) 5.0% 2.5% 1.5% 5.0% 2.5% 1.5% 3.0% 1.5% 1.0% 7.5% 2.0% 1.0%

Precision CV (%) 5.0% 2.0% 1.5% 5.0% 2.0% 1.0% 2.0% 1.0% 1.0% 3.5% 1.0% 1.0%

For pipetting of less than 10µL HAMILTON recommends 10µL/50µL volume disposable tips to achieve highest pipetting precision.

Capacitive liquid level detection (cLLD) (Pressure liquid level detection (pLLD)

Replication of one 96-well plate, with cLLD on aspiration: 35s (incl. new tips)
Reformatting of four 96-well plates to one 384-well plate, 50 µL, new tips, with cLLD on aspiration: 140s 8-12 positions Ethernet

15o to 35oC (59o to 95oF) 30% to 85% R.H. non-condensing 2000 m (1.2 miles) above sea level

-20oC (-4.0oF) @ 10% humidity to 70oC (158oF) @ 90% humidity non-condensing

II 2
microtiter footprint plate height < 43 mm

Specifications: NIMBUS4

NIMBUS4 Labware Gripper Specifications:

Parameter
Plate format
Absolute positioning
Gripping force Transport mass Operating Data

Specification

microtiter footprint plate height < 43 mm

accuracy

X, Y, Z = 0.5 mm

reproducibility X, Y, Z = 0.25

5 N ­ 16 N (default 9 N): Independent Channels Gripper Landscape 190220

300g filled deep-well plate

Temperature range Relative humidity Altitude

15°C ­ 35°C 30% ­ 85% (non-condensing, indoors) 2000 m above sea level

NIMBUS4 Dimensions

27

Hamilton Company is focused on blending innovation and accuracy to deliver customers
unparalleled products.

© 2014 Hamilton Company. All rights reserved. All trademarks are owned and/or registered by Hamilton Company in the U.S. and/or other countries.
Version 1. Lit. No. BR0001-- 06/2014 QTY: X,XXX Printed in U.S.A.

Web: www.hamiltonrobotics.com
USA: 800-648-5950
Email: infoservice@hamiltonrobotics.com

United States Tel: +1-775-858-3000
United Kingdom & Ireland Tel: +44 (0)121-717-0199
Brazil Tel: +55 (11) 9677-4093

China Tel: +86-21-6164-6567
France Tel: +33 (01) 69751616
Italy Tel: +39-39-689-33-93

Denmark, Norway, Sweden, Finland Tel: +45-70-26-4499
Germany, Switzerland, Austria, Benelux Tel: +49 (089) 552649-0

To find a subsidiary or distributor in your area, please visit hamiltonrobotics.com/contacts.


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