1. Introduction
The ASUS Prime B760-PLUS D4 motherboard is designed to support Intel 13th and 12th Generation Core processors, utilizing the LGA 1700 socket. This ATX motherboard features PCIe 5.0 support, three PCIe 4.0 M.2 slots, DDR4 memory compatibility, and a Realtek 2.5Gb Ethernet port. It also includes advanced connectivity options such as rear USB 3.2 Gen 2x2 Type-C and front USB 3.2 Gen 1 Type-C, with support for a Thunderbolt (USB4) header. This manual provides essential information for the installation, operation, and maintenance of your motherboard.

Image 1.1: The ASUS Prime B760-PLUS D4 motherboard alongside its retail packaging, showcasing the overall design and branding.
2. Package Contents
Verify that all components listed below are present in your motherboard package. If any item is missing or damaged, contact your retailer.
- ASUS Prime B760-PLUS D4 Motherboard
- Rear I/O Panel Shield
- SATA Cables
- M.2 Screw Package
- M.2 Rubber Package
- User Guide

Image 2.1: An illustration of the typical contents found within the ASUS Prime B760-PLUS D4 motherboard package, including the motherboard, I/O shield, cables, and documentation.
3. Setup and Installation
Before beginning installation, ensure your system is powered off and disconnected from the power source. Handle the motherboard by its edges to avoid static discharge.
3.1 CPU Installation
This motherboard supports Intel LGA 1700 socket processors. Carefully align the CPU with the socket, ensuring the notches on the CPU match the keys on the socket. Lower the CPU gently into place without forcing it. Close the load plate and secure the retention lever.
3.2 Memory (RAM) Installation
The ASUS Prime B760-PLUS D4 features four DDR4 DIMM slots, supporting dual-channel memory configurations. Open the retention clips on both ends of the DIMM slot. Align the memory module with the slot, ensuring the notch on the module matches the key on the slot. Press down firmly on both ends of the memory module until the retention clips snap into place.

Image 3.1: An overhead view of the motherboard highlighting the four DDR4 DIMM slots and various expansion slots, including PCIe 5.0 x16 and M.2 slots.
3.3 Storage Device Installation (M.2 and SATA)
The motherboard includes three PCIe 4.0 M.2 slots for high-speed NVMe SSDs. To install an M.2 SSD, insert it into the M.2 slot at an angle, then gently push it down and secure it with the provided M.2 screw or Q-Latch mechanism. For SATA drives, connect the SATA data cable to the motherboard's SATA ports and the drive, and connect the power cable from your power supply.

Image 3.2: Close-up of an M.2 slot featuring the ASUS Q-Latch mechanism for tool-less SSD installation.
3.4 Expansion Card Installation
The motherboard features one PCIe 5.0 x16 SafeSlot Core+ for graphics cards, one PCIe 4.0 x16 slot (max @x4), and two PCIe 3.0 x1 slots. Align your expansion card with the desired PCIe slot and press firmly until it is seated correctly. Secure the card with a screw to your chassis.
3.5 Power Connections
Connect the 24-pin ATX power connector and the 8-pin CPU power connector from your power supply to the corresponding ports on the motherboard. Ensure all connections are secure.
3.6 Front Panel and Peripheral Connections
Connect your chassis's front panel connectors (power button, reset button, HDD LED, power LED) to the designated headers on the motherboard. Connect USB 2.0, USB 3.2 Gen 1, and USB 3.2 Gen 1 Type-C front panel cables as appropriate. The motherboard also supports a Thunderbolt (USB4) header.

Image 3.3: A detailed view of the rear I/O panel, showing ports for HDMI, DisplayPort, VGA, USB 2.0, USB 3.2 Gen 1 Type-A, USB 3.2 Gen 2x2 Type-C, 2.5Gb Ethernet, and audio jacks.

Image 3.4: The motherboard highlighting the onboard Addressable Gen 2 headers and Aura RGB header for connecting LED strips, along with audio features like shielding and premium capacitors.
4. Operating Instructions
4.1 Initial Boot and BIOS/UEFI Setup
After assembling your system, power it on. During startup, press the DEL or F2 key to enter the BIOS/UEFI setup utility. Here, you can configure boot order, system time, and other advanced settings. Refer to the ASUS website for detailed BIOS/UEFI guides.
4.2 Driver Installation
After installing your operating system, it is crucial to install the latest drivers for your motherboard components. These include chipset drivers, LAN drivers (for the Realtek 2.5Gb Ethernet), audio drivers, and any other necessary device drivers. Visit the official ASUS support website for the PRIME B760-PLUS D4 model to download the most up-to-date drivers. Installing drivers from the manufacturer's website ensures optimal performance and stability.
5. Maintenance
Regular maintenance helps ensure the longevity and stable operation of your motherboard.
- Dust Removal: Periodically clean dust from the motherboard and components using compressed air. Ensure the system is powered off and unplugged before cleaning.
- BIOS/UEFI Updates: Check the ASUS support website for BIOS/UEFI updates. Updates can improve compatibility, stability, and performance. Follow the provided instructions carefully when updating.
- Driver Updates: Keep all drivers updated to their latest versions to ensure optimal performance and resolve potential issues.
- Cooling System Check: Ensure all fans (CPU, chassis, AIO pump) are functioning correctly and free from obstructions. The motherboard features VRM heatsinks, M.2 heatsinks, and a PCH heatsink for comprehensive cooling.

Image 5.1: The motherboard with key cooling components labeled, including VRM heatsinks, M.2 heatsink, PCH heatsink, and various fan headers.
6. Troubleshooting
If you encounter issues with your motherboard, consider the following common troubleshooting steps:
- No Power:
- Ensure all power cables (24-pin ATX, 8-pin CPU) are securely connected.
- Verify the power supply is switched on and functioning.
- Check front panel power button connection.
- No Display:
- Confirm the monitor is connected to the graphics card (or integrated graphics port) and powered on.
- Reseat the graphics card and memory modules.
- Try booting with only one memory stick.
- System Instability/Crashes:
- Ensure all drivers are up to date.
- Check CPU and GPU temperatures.
- Verify memory compatibility and stability (run memory diagnostic tools).
- Reset BIOS to default settings.
- Peripheral Not Detected:
- Ensure the device is properly connected.
- Install necessary drivers for the peripheral.
- Try a different port.
For more advanced troubleshooting, consult the comprehensive user manual available on the ASUS support website or contact ASUS technical support.
7. Specifications
| Feature | Detail |
|---|---|
| Brand | ASUS |
| Model Name | PRIME B760-PLUS D4 |
| CPU Socket | LGA 1700 |
| Compatible Processors | 13th Gen Intel Core, 12th Gen Intel Core |
| Chipset Type | Intel B760 |
| RAM Memory Technology | DDR4 |
| Memory Speed | 2133 MHz (Base), Supports higher OC speeds |
| Memory Storage Capacity (Max) | 64 GB |
| PCIe Slots | 1x PCIe 5.0 x16, 1x PCIe 4.0 x16 (max @x4), 2x PCIe 3.0 x1 |
| M.2 Slots | 3x PCIe 4.0 M.2 slots |
| LAN | Realtek 2.5Gb Ethernet |
| Rear USB Ports | USB 3.2 Gen 2x2 Type-C, USB 3.2 Gen 2 Type-A, USB 3.2 Gen 1 Type-A, USB 2.0 Type-A |
| Front USB Headers | USB 3.2 Gen 1 Type-C, USB 3.2 Gen 1, USB 2.0 |
| Video Outputs | DisplayPort, HDMI, VGA |
| Dimensions (LxWxH) | 10.5 x 2.1 x 13 inches (approx.) |
| Item Weight | 2.4 pounds |
| Platform | Windows 10 (Compatible with Windows 11) |
8. Support and Warranty Information
For technical support, driver downloads, BIOS updates, and further product information, please visit the official ASUS support website. You can find detailed FAQs, troubleshooting guides, and contact information for customer service.
ASUS Support Website: https://www.asus.com/support/
Information regarding the product warranty is typically provided with your purchase documentation. Please refer to the warranty card or the ASUS official website for specific terms and conditions applicable to your region.





