1. Introduction
This user manual provides comprehensive instructions for the installation, configuration, and maintenance of the ASUS Prime H610M-K D4 micro-ATX motherboard. Designed for Intel LGA 1700 socket processors, this motherboard offers essential features for building a reliable computing system. Please read this manual thoroughly before proceeding with installation to ensure proper setup and operation.

Figure 1: ASUS Prime H610M-K D4 Motherboard and its retail packaging.
2. Package Contents
Verify that all items listed below are present in your motherboard package. If any item is missing or damaged, contact your retailer.
- ASUS Prime H610M-K D4 Motherboard
- Rear I/O Panel Shield
- User Guide
- Support DVD
- SATA Data Cables (Quantity may vary)
- M.2 Anchor/Screw Package

Figure 2: Included accessories and the motherboard in the package.
3. Key Features
The ASUS Prime H610M-K D4 motherboard incorporates several features designed for performance and reliability:
- Intel LGA 1700 Socket: Compatible with 12th Generation Intel processors.
- Comprehensive Cooling: Features a PCH heatsink and Fan Xpert for optimized thermal management.
- Ultrafast Connectivity: Includes a 32Gbps M.2 slot, Realtek 1 Gb Ethernet, and USB 3.2 Gen 1 support.
- 5X Protection III: Multiple hardware safeguards provide all-round protection for system components.
3.1. Connectivity Overview

Figure 3: Rear I/O panel and internal connectivity options including USB, HDMI, D-Sub, Ethernet, and audio jacks.
The motherboard provides a range of connectivity options including USB 3.2 Gen 1 ports, HDMI, D-Sub for video output, Realtek 1 Gb Ethernet for network access, and multiple audio jacks. Internal headers support additional USB ports and front panel connections.
3.2. Power Delivery and Cooling

Figure 4: Location of the 8-pin PWR connector and 4-pin onboard PWM/DC fan headers.
The motherboard features an 8-pin power connector for CPU power and multiple 4-pin PWM/DC fan headers to manage system cooling effectively. These headers allow for precise control over fan speeds to maintain optimal temperatures.
3.3. Expansion and Storage

Figure 5: Location of 2 x DIMM slots for DDR4 memory, 1 x M.2 NVMe SSD slot, and PCIe 4.0 X16 slot.
The motherboard supports up to 64GB of DDR4 memory across two DIMM slots. It includes one M.2 slot for NVMe SSDs, supporting PCIe 3.0 x4 and SATA modes, and a PCIe 4.0 x16 SafeSlot Core for graphics cards. Four SATA 6Gbps ports are also available for traditional storage devices.
3.4. Customization Options

Figure 6: Location of the 4-pin RGB header for connecting compatible lighting devices.
An onboard 4-pin RGB header allows for connection and synchronization of compatible RGB lighting components, enabling aesthetic customization of your PC build.
4. Setup and Installation
Before installing the motherboard, ensure your system is powered off and disconnected from the power outlet. Always handle components with care and use anti-static precautions.
4.1. CPU Installation
- Open the CPU socket lever and remove the protective cover.
- Carefully align the CPU with the socket, ensuring the triangular mark on the CPU matches the mark on the socket.
- Gently place the CPU into the socket without forcing it.
- Close the socket lever to secure the CPU.
- Install the CPU cooler according to its manufacturer's instructions.
4.2. Memory (RAM) Installation
- Open the clips at both ends of the DIMM slot.
- Align the notch on the DDR4 memory module with the key in the DIMM slot.
- Insert the memory module firmly into the slot until the clips snap into place.
4.3. Storage Device Installation
4.3.1. M.2 SSD Installation
- Locate the M.2 slot on the motherboard.
- Remove the M.2 screw/standoff from the motherboard.
- Insert the M.2 SSD into the slot at a 30-degree angle.
- Push the SSD down and secure it with the M.2 screw/standoff.
4.3.2. SATA Drive Installation
- Connect one end of the SATA data cable to a SATA port on the motherboard.
- Connect the other end of the SATA data cable to your SATA hard drive or SSD.
- Connect a SATA power cable from your power supply unit (PSU) to the SATA drive.
4.4. Power Connections
- Connect the 24-pin ATX power connector from your PSU to the corresponding header on the motherboard.
- Connect the 8-pin ATX 12V power connector from your PSU to the corresponding header near the CPU socket.
4.5. Front Panel and I/O Connections
- Connect the front panel headers (power switch, reset switch, HDD LED, power LED) to the designated pins on the motherboard. Refer to the user guide for exact pin assignments.
- Connect USB 2.0 and USB 3.2 Gen 1 front panel cables to their respective headers.
- Connect the front panel audio cable to the AAFP header.
- Install the rear I/O panel shield into your PC case before mounting the motherboard.
5. Operating Instructions
5.1. First Boot
- After completing all hardware installations, connect your monitor, keyboard, and mouse.
- Connect the power cord to your PSU and turn on the power switch.
- Press the power button on your PC case.
- The system should boot and display the ASUS logo. Press Del or F2 during POST to enter the BIOS/UEFI setup.
5.2. BIOS/UEFI Setup
The BIOS (Basic Input/Output System) or UEFI (Unified Extensible Firmware Interface) allows you to configure system settings, boot order, and hardware parameters.
- Main: View system information.
- Ai Tweaker: Adjust CPU and memory settings (for advanced users).
- Advanced: Configure peripheral settings, storage modes (AHCI/RAID), and other advanced features.
- Monitor: Monitor system temperatures, fan speeds, and voltages.
- Boot: Set boot priorities for your operating system drive.
- Tool: Access utilities like ASUS EZ Flash 3 for BIOS updates.
- Exit: Save changes and exit, or discard changes and exit.
For detailed information on BIOS settings, refer to the comprehensive user manual provided on the support DVD or ASUS website.
6. Maintenance
6.1. Cleaning
Regularly clean your PC to prevent dust buildup, which can lead to overheating and reduced performance.
- Power off and unplug your computer before cleaning.
- Use compressed air to remove dust from fans, heatsinks, and other components.
- Wipe exterior surfaces with a soft, damp cloth. Avoid using harsh chemicals.
6.2. BIOS Updates
BIOS updates can improve system stability, add support for new hardware, or fix bugs.
- Download the latest BIOS version for your specific motherboard model from the official ASUS support website.
- Use the ASUS EZ Flash 3 utility within the BIOS to perform the update. Follow the on-screen instructions carefully.
- Caution: Do not interrupt the BIOS update process, as this can render your motherboard inoperable.
7. Troubleshooting
This section addresses common issues you might encounter during setup or operation.
| Problem | Possible Cause | Solution |
|---|---|---|
| No display on monitor. | Incorrect video cable connection, faulty GPU, or monitor input. |
|
| System powers on but does not boot. | Incorrect boot device, faulty RAM, or CPU. |
|
| USB devices not recognized. | Driver issues, faulty port, or incorrect connection. |
|
For more advanced troubleshooting, consult the full user manual or the ASUS support website.
8. Specifications
| Feature | Detail |
|---|---|
| Brand | ASUS |
| Model Name | PRIME H610M-K D4 |
| CPU Socket | LGA 1700 |
| Chipset | Intel H610 |
| RAM Memory Technology | DDR4 |
| Memory Slots | 2 x DIMM, Max. 64GB, DDR4 |
| PCIe Slots | 1 x PCIe 4.0 x16 slot |
| Storage | 1 x M.2 slot (PCIe 3.0 x4 & SATA modes), 4 x SATA 6Gb/s ports |
| USB Ports (Rear) | 2 x USB 3.2 Gen 1, 2 x USB 2.0 |
| Video Outputs | 1 x HDMI, 1 x D-Sub (VGA) |
| Ethernet | Realtek 1Gb Ethernet |
| Audio | Realtek 7.1 Surround Sound High Definition Audio CODEC |
| Form Factor | Micro-ATX (7.99 x 9.21 inches) |
| Item Weight | 1.06 pounds |
9. Warranty and Support
ASUS provides a limited warranty for this product. The specific terms and conditions of the warranty may vary by region. Please refer to the warranty card included in your package or visit the official ASUS website for detailed warranty information.
For technical support, driver downloads, and further documentation, please visit the official ASUS support website: www.asus.com/support/.





