1. Introduction
This user manual provides comprehensive instructions for the installation, operation, and maintenance of your ASUS H110M-D motherboard. Designed for Intel Core i7/i5/i3 processors with an LGA1151 socket, this micro-ATX motherboard supports DDR4 memory and features PCI Express and SATA connectivity. Please read this manual thoroughly before beginning installation to ensure proper setup and optimal performance.
2. Safety Information
Always observe the following safety precautions:
- Disconnect the power cord from the wall outlet before touching any components.
- Wear an anti-static wrist strap or frequently touch a grounded metal object to discharge static electricity before handling components.
- Handle components by their edges to avoid touching sensitive parts.
- Ensure proper ventilation within your PC case to prevent overheating.
- Keep the motherboard away from moisture and extreme temperatures.
3. Package Contents
Verify that all items are present in your package:
- ASUS H110M-D Motherboard
- I/O Shield
- SATA 6Gb/s Cables
- Support DVD (Drivers and Utilities)
- User Manual (this document)
4. Component Overview
Familiarize yourself with the key components and connectors on your ASUS H110M-D motherboard.

Figure 4.1: ASUS H110M-D Motherboard Layout
This image displays the full layout of the ASUS H110M-D motherboard, highlighting key areas such as the CPU socket, DDR4 DIMM slots, PCIe slots, SATA ports, and various headers. The CPU socket area includes a warning to install the processor first and keep the protective cover.
Key Components:
- LGA1151 CPU Socket: Supports Intel 6th and 7th Generation Core i7/i5/i3/Pentium/Celeron Processors.
- DDR4 DIMM Slots (2): Supports up to 32GB of DDR4 2133MHz non-ECC, un-buffered memory.
- PCIe 3.0 x16 Slot (1): For graphics cards.
- PCIe 2.0 x1 Slots (2): For expansion cards.
- SATA 6Gb/s Ports (4): For connecting storage devices.
- Rear I/O Ports: Includes USB 3.0, USB 2.0, HDMI, VGA, LAN, and audio jacks.
- Front Panel Headers: USB 3.0, USB 2.0, Audio, System Panel.
5. Setup and Installation
Follow these steps for proper installation of your motherboard and components.
5.1. CPU Installation
Important: Install the processor FIRST, then remove and keep the protective cover from the CPU socket. This cover should be re-installed if the processor is removed or the motherboard is returned.
- Open the CPU socket lever and lift the load plate.
- Carefully align the CPU with the socket, ensuring the golden triangle on the CPU matches the triangle on the socket.
- Gently place the CPU into the socket. Do not force it.
- Lower the load plate and secure it with the lever.
- Apply thermal paste and install the CPU cooler.
5.2. Memory (RAM) Installation
This motherboard supports DDR4 memory modules.
- Open the clips at both ends of the DIMM slot.
- Align the notch on the DDR4 module with the key on the DIMM slot.
- Insert the module firmly into the slot until the clips snap into place.
5.3. Storage Device Installation (SATA)
Connect your SATA hard drives or SSDs to the SATA 6Gb/s ports.
- Connect one end of the SATA data cable to a SATA port on the motherboard.
- Connect the other end to your storage device.
- Connect the SATA power cable from your power supply to the storage device.
5.4. Expansion Card Installation (PCIe)
Install your graphics card or other expansion cards into the PCIe slots.
- Align the expansion card with the desired PCIe slot.
- Press down firmly until the card is securely seated in the slot.
- Secure the card with a screw to the PC case.
5.5. Power Connections
Connect the power supply cables to the motherboard.
- 24-pin ATX Power Connector: Connect the main 24-pin power cable from your power supply.
- 8-pin ATX 12V Power Connector: Connect the 8-pin (or 4+4 pin) CPU power cable.
6. Operating Instructions
6.1. Initial Boot
After all components are installed and connected, you can power on your system.
- Ensure all cables are securely connected.
- Connect the power cord to the power supply and a wall outlet.
- Press the power button on your PC case.
- The system should boot and display the ASUS logo.
6.2. BIOS Setup
The BIOS (Basic Input/Output System) allows you to configure system settings.
- During boot-up, press the DEL key or F2 key to enter BIOS Setup.
- Navigate through the menus using arrow keys.
- Save changes and exit to restart the system.
7. Maintenance
7.1. Cleaning
Regular cleaning helps maintain optimal performance and longevity.
- Ensure the system is powered off and unplugged before cleaning.
- Use compressed air to remove dust from fans, heatsinks, and other components.
- Wipe surfaces with a soft, dry, lint-free cloth. Avoid liquid cleaners.
7.2. BIOS Updates
Periodically check the ASUS support website for BIOS updates to improve compatibility and performance.
- Download the latest BIOS file from the official ASUS support page for your model.
- Follow the instructions provided by ASUS for the specific BIOS update utility (e.g., EZ Flash).
8. Troubleshooting
| Problem | Possible Solution |
|---|---|
| System does not power on. | Check power supply connections (24-pin and 8-pin). Ensure power button cable is correctly connected to the front panel header. Test power supply. |
| No display on monitor. | Ensure graphics card (if used) is properly seated and powered. Check monitor cable connection. Try reseating RAM modules. |
| System reboots unexpectedly. | Check CPU cooler installation and thermal paste. Verify power supply stability. Run memory diagnostic tests. |
| Operating system not found. | Check SATA cable connections to storage devices. Verify boot order in BIOS. Ensure OS is properly installed. |
9. Specifications
| Feature | Detail |
|---|---|
| Model Name | H110M-D |
| CPU Socket | LGA 1151 |
| Chipset | Intel H110 |
| Compatible Processors | Intel Core i7/i5/i3/Pentium/Celeron (6th & 7th Gen) |
| Memory Type | DDR4 2133MHz, Non-ECC, Un-buffered |
| Memory Slots | 2 x DIMM, Max. 32GB |
| PCIe Slots | 1 x PCIe 3.0 x16, 2 x PCIe 2.0 x1 |
| Storage | 4 x SATA 6Gb/s ports |
| USB Ports | USB 3.0, USB 2.0 |
| Video Outputs | HDMI, VGA |
| LAN | Realtek RTL8111H Gigabit LAN Controller |
| Audio | Realtek ALC887 8-Channel High Definition Audio CODEC |
| Form Factor | micro-ATX (8.9 inch x 7.3 inch) |
| Dimensions | 4.33 x 4.33 x 1.18 inches |
| Weight | 13.1 ounces |
10. Warranty and Support
For detailed warranty information, please refer to the warranty card included with your product or visit the official ASUS support website. ASUS provides technical support and resources for its products.
- ASUS Support Website: www.asus.com/support/
- Product Registration: Register your product online to receive the latest updates and support.





