1. Introduction and Overview
The Antec ISK110 VESA is a compact Mini-ITX computer case designed for small, efficient system builds. It features a slim profile and includes a VESA mount for flexible installation options, making it suitable for various applications such as corporate, commercial, and home theater personal computer (HTPC) environments. The case is engineered to provide adequate cooling and performance within its small footprint.
Key Features:
- Compact and slim design with included VESA mount.
- Two 2.5-inch internal drive bays for SSDs or small form factor HDDs.
- Front panel with four USB 2.0 ports and audio input/output.
- Pre-installed 90-watt external power adapter with up to 92% efficiency.
- Compatible with most Mini-ITX motherboard solutions.

Figure 1.1: Front and side view of the Antec ISK110 VESA Mini-ITX Case with the VESA mounting bracket attached.
2. Setup Instructions
2.1. Preparing the Case
- Carefully remove the side panels of the case. The panels are typically secured with screws at the rear.
- Ensure all internal cables are accessible for motherboard and drive connections.

Figure 2.1: Internal view of the Antec ISK110 case, illustrating the layout for component installation.
2.2. Motherboard Installation
- Install your Mini-ITX motherboard into the designated area within the case. Ensure proper alignment with the I/O shield.
- Secure the motherboard using the provided screws.
- Connect the necessary power cables (24-pin ATX, 4-pin CPU) from the pre-installed 90-watt power adapter to the motherboard.
- Connect the front panel headers (power switch, reset switch, USB 2.0, audio) to the corresponding pins on your motherboard. Refer to your motherboard manual for pin assignments.
2.3. Drive Installation
- The case supports two 2.5-inch drives (SSDs or HDDs). Locate the 2.5-inch drive bays, typically behind the motherboard tray.
- Mount your 2.5-inch drives into the bays using the provided screws.
- Connect SATA data cables from the motherboard to the drives.
- Connect SATA power cables from the internal power supply to the drives.
2.4. VESA Mount Installation
The included VESA mount allows for flexible placement, such as mounting the case behind a compatible monitor.
- Attach the VESA mounting bracket to the rear of your VESA-compatible monitor using the appropriate screws.
- Slide the Antec ISK110 VESA case onto the bracket until it securely locks into place.
3. Operating Instructions
3.1. Powering On/Off
- Connect the external 90-watt power adapter to the case and then to a power outlet.
- Press the power button located on the front panel of the case to turn on your system.
- To turn off, use the operating system's shutdown function or press and hold the power button for several seconds.

Figure 3.1: Front panel of the Antec ISK110 case, highlighting the power button and four USB 2.0 ports.
3.2. Connecting Peripherals
The front panel provides convenient access for connecting various peripherals:
- USB 2.0 Ports: Four USB 2.0 ports are available for keyboards, mice, external storage, and other USB devices.
- Audio Jacks: Dedicated audio input (microphone) and output (headphone) jacks are present for audio peripherals.
4. Maintenance
4.1. Dust Management
Regular cleaning is essential to maintain optimal performance and prevent overheating. Dust accumulation can impede airflow and reduce cooling efficiency.
- Periodically clean the exterior of the case with a soft, dry cloth.
- For internal cleaning, power off and unplug the system. Remove the side panels and use compressed air to gently remove dust from components, especially CPU heatsinks and any ventilation areas.
- Ensure all vents are clear of obstructions to allow for proper airflow.
4.2. Cable Management
Due to the compact nature of the ISK110 VESA, effective cable management is important for airflow and ease of access. Ensure cables are routed neatly and do not obstruct fans or ventilation paths.
5. Troubleshooting
5.1. System Not Powering On
- Verify that the external power adapter is securely connected to both the case and a working power outlet.
- Check that the 24-pin ATX and 4-pin CPU power cables are correctly seated on the motherboard.
- Ensure the front panel power switch cable is correctly connected to the motherboard's power header pins.
5.2. Overheating Concerns
- Confirm that the CPU cooler is properly installed and functioning.
- Ensure all internal cables are managed to allow for unobstructed airflow.
- Clean any dust accumulation from internal components and ventilation openings.
- Verify that the case is placed in an area with adequate ventilation and not enclosed in a tight space.
5.3. Drive Detection Issues
- Check that the SATA data and power cables are securely connected to both the drives and the motherboard/power supply.
- Ensure the drives are properly seated in their bays.
6. Specifications
| Feature | Specification |
|---|---|
| Brand | Antec |
| Model Name | ISK110 VESA-U3 |
| Item Model Number | ISK110-VESA |
| Motherboard Compatibility | Mini ITX |
| Case Type | Slim-Desktop |
| Drive Bays | 2 x 2.5" Internal |
| Front I/O Ports | 4 x USB 2.0, Audio In/Out |
| Power Supply | External 90W Adapter |
| Material | Alloy Steel, ABS Plastic |
| Color | Black |
| Item Weight | 2.9 pounds (1.32 kg) |
| Product Dimensions (LxWxH) | 8.4 x 3.1 x 8.7 inches (21.3 x 7.9 x 22.1 cm) |
| Cooling Method | Air |
| Special Features | VESA Mount Included, Case Lock Slot |
7. Warranty Information
The Antec ISK110 VESA Mini-ITX Case is backed by a manufacturer's three-year limited warranty. This warranty covers defects in materials and workmanship under normal use. Please retain your proof of purchase for warranty claims. For specific terms and conditions, refer to the official Antec warranty documentation or contact Antec customer support.
8. Support
For technical assistance, product inquiries, or warranty support regarding your Antec ISK110 VESA Mini-ITX Case, please visit the official Antec website or contact their customer service department. Detailed contact information and support resources can typically be found on the Antec corporate website.





