LABCONCO Logic Series Class II Biological Safety Cabinets

Specifications

• Models: 30231xxx2, 30238xxx2, 30232xxx2, 30241xxx2, 30248xxx2, 30242xxx2, 30348xxx2, 30251xxx2, 30258xxx2, 30252xxx2, 30261xxx2, 30268xxx2, 30262xxx2, 30368xxx2
• Logic models may produce up to the following BTU/hr for different sash heights:
  • 3′ Type A2 Logic: 452, 515, 606 BTU/hr
  • 4′ Type A2 Logic: 556, 647, 750 BTU/hr
  • 5′ Type A2 Logic: 647, 838, 1068 BTU/hr
  • 6′ Type A2 Logic: 1093, 1313, 1535 BTU/hr
  • 4′ Type B2 Logic: 330 BTU/hr
  • 6′ Type B2 Logic: 1225 BTU/hr

Product Usage Instructions

1. Site Planning:
   • Ensure the Logic is located in a room with closed windows.
   • Place the cabinet away from heavy foot traffic, doors, fans, and ventilation registers.
2. Mounting Surface:
   • Ensure proper accommodations are made for placing the Logic on suitable cabinetry or stand.
3. Space Requirements:
   • Refer to Appendix B in User’s Manual for adequate floor space.
   • Ensure proper overhead clearance for the Logic.
4. Exhaust Requirements:
   • Review applications with the Safety Officer if exhausting to the outside is required.
   • Get approval from a facilities manager or HVAC person for exhaust system placement.
   • Order necessary exhaust components if required.
   • Evaluate room/building for adequate air changes.
   • Consider heating and cooling load during planning.

FAQs

• Q: Who should be responsible for the validation process?
  • A: The validation process should be fully carried out prior to use of the BSC. Records should be stored in a safe, easily retrievable location. The company’s quality system should document the BSC’s location, preventive maintenance schedules, and certification schedules.
• Q: Can Labconco assist with installation and validation processes?
  • A: Labconco’s Product Service Representatives and Application Specialists can provide information on purchase, delivery, and installation. However, Labconco is not responsible for carrying out the actual installation or validation processes.

IQ/OQ/PQ Protocol Installation Qualification/ Operation Qualification/ Performance Qualification
Logic® Series Class II Biological Safety Cabinets
Labconco No. ­ 1058606, Rev. A, ECO P392 Available at labconco.com

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

Purpose and Scope

This Qualification Protocol is solely intended to be used with Labconco Logic Series Biological Safety Cabinets, which are new or relocated. It is written to assist the enduser in validation of predetermined specifications. The protocol begins with planning the site for the piece of equipment and therefore is of value prior to receipt of delivery.

Models:

30231xxx2 30238xxx2 30232xxx2

30241xxx2 30248xxx2 30242xxx2 30348xxx2

30251xxx2 30258xxx2 30252xxx2

30261xxx2 30268xxx2 30262xxx2 30368xxx2

Responsibilities

End-User ­ The end user or equipment owner is responsible for ensuring that the BSC is installed and operating properly. This document can assist in that validation. This document cannot however anticipate every application or unique situation encountered with the installation and operation. It is therefore essential that users, lab managers and safety officers work together to broaden the scope of this document through cautious forethought.

End-User Employer ­ The employer is responsible for supporting the validation through adequate resources and training. The organization shall also ensure the
validation process has been fully carried out prior to use of the BSC. Records should be
stored in a safe, easily retrievable location. The location of the BSC, preventive maintenance and certification schedules should be documented in the company’s quality system.

Cabinet Certifier ­ All BSCs must be certified prior to use. A qualified certifying technician must do this process with calibrated instruments. The cabinet must be certified upon installation, on a scheduled annual basis and whenever the cabinet is moved to a new location. Certification is the key requirement of this protocol.

Manufacturer ­ Labconco Corporation, certified ISO 9001, is responsible to fully test the Logic BSC to NSF 49 requirements prior to shipment. The manufacturer must retain
these records. Labconco’s Product Service Representatives and Application Specialists can assist with information on the purchase, delivery and installation. Labconco is not
responsible for carrying out the actual installation or validation processes.

1

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A
Performance Qualification
Once the Logic has been checked for proper installation and operation, its performance may be validated. Labconco cannot recommend specific procedures to perform additional validation. Any performance validation should be designed to meet the specifications and accuracy required of the BSCs application. In general, additional validation may involve establishing acceptance criteria, inspecting and testing the results with calibrated equipment and qualified personnel. Some basic suggestions are included after the Operational Qualification section.
2

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

A. Installation Qualification

Step 1 1a
1b 1c
1d

Description Specification or Acceptance Criteria

Site Planning

Proper airflows

Is the Logic to be located in a room with windows that will remain closed?

Is the cabinet to be located away from heavy foot traffic, doors, fans, ventilation registers and any other air-handling devices that could disrupt its airflow patterns?

Mounting Surface

Have accommodations been made for placement of the Logic on cabinetry or stand of suitable strength and proper height?

Space

Refer to Appendix B in User’s Manual. Has

Requirements adequate floor space been provided for

placement of the cabinet?

Is there proper overhead clearance for the Logic? There must be 6-inches, (150 mm) above the exhaust cover for units not connected to exhaust systems.

Exhaust Requirements

Certain applications require the BSC to be exhausted to the outside. Have the applications been reviewed with the Safety Officer?

For cabinets to be connected to exhaust systems, has a facilities manager or qualified HVAC person reviewed and approved the site plans for placement of exhaust duct?

For units requiring exhausting to the outside, have the exhaust blower, ductwork, dampers, and canopy connection been ordered?

Has the room/building been evaluated for adequate air changes with the device?

For units installed on adjustable height base stands, have accommodations been made for flexible ducting?

Result YES NO
Y N Y N
Y N Y N Y N
Y N
Y N N/A
Y N N/A
Y N Y N N/A

3

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

Y N

Has the heating and cooling load been

considered in the planning? Logic models

N/A

may produce up to the following BTU/hr for

8″, 10″, 12″ sash heights

3′ Type A2 Logic = 452, 515, 606 BTU/hr 4′ Type A2 Logic = 556, 647, 750 BTU/hr 5′ Type A2 Logic = 647, 838, 1068 BTU/hr 6′ Type A2 Logic = 1093, 1313, 1535 BTU/hr 4′ Type B2 Logic = 330 BTU/hr 6′ Type B2 Logic = 1225 BTU/hr

1e Gas Services Has the facilities manager been consulted with regard to gas/vacuum requirements?
Does the BSC ordered/received have service valves to match expectations?

Y N N/A
Y N N/A

Connections to service valves are ¼” OD metal and require a shut-off valve.

WARNING: The use of flammable gasses or solvents within the BSC should be avoided. Excessive heat may alter the laminar airflow and could potentially damage the HEPA filter. A Safety Officer should approve the use of flammable materials within the cabinet.

1f Electrical Service

For BSCs installed on adjustable height base stands, have accommodations been made for flexible service lines?

Y N N/A

Refer to the Electrical Requirements section Y N of the User’s Manual for a list of model numbers and their corresponding electrical ratings. Are services available for the BSC to be connected to a dedicated circuit with over-current protection of adequate size and the proper voltage?

4

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

1g Delivery

If the BSC has not been delivered yet, have Y N

Requirements arrangements been made with the facility or

delivery agent to have equipment capable of

gently handling a packaged skid of this size

and weight?

Is there a clear path from the loading platform to the final destination in the lab?

Y N

When required, will there be equipment to move the cabinet onto the final mounting surface/stand?

Y N

2

Prior to

Operation

2a Damage Claims

Has the BSC has been inspected for any

Y N

signs of damage that may have occurred

while in transit or within the building? Keep

packaging materials until inspection is

complete.

2b Set Up

If so, refer to the User’s Manual for information on shipping damage claims.

Has the cabinet been mounted to a

Y N

substantial supporting stand or cabinet that

has been checked for level?

Is the cabinet or stand set at a suitable height for the operator to work ergonomically?

Y N

Before attempting to operate the sash, remove the side panels and verify the following:

Y N

Are the sash cables centered on the pulleys?
Has the weight restraining pin under each weight been removed and discarded?

See Installation Instruction Sheet affixed to the sash for photos and details.

5

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

The User’s Manual and Small Parts Kit are

Y

N

shipped under the work surface. Have these

been unpacked and stored for future use?

2c Drain Valve If the optional Drain Valve provided is to be Y N

installed, has it been sealed and fastened to

the underside of the work surface per the

N/A

User’s Manual.

2d Electrical

Is the BSC connected to a dedicated

Y N

Connections electrical circuit of proper voltage and

amperage? See identification plate on the

front surface of the electrical box above the

front panel.

Duplex receptacle(s) inside the cabinet are Y N operational? Do the GFI test and reset buttons work properly (115V models only)? N/A

2e Gas Services Has a qualified technician installed the

Y N

gas/vacuum services? Checked for leaks? N/A

Have the valves been labeled appropriately?

Y N N/A

2f Exhaust System

If exhausted to the outside, has a qualified installer completed the connections to the BSC?

Y N N/A

If exhausted to the outside, is the exhaust system to the BSC ON continuously?

Y N N/A

If the answer is NO, has the exhaust system

ON/OFF control been validated to ensure

Y N

BSC and remote exhaust system are

N/A

communicating as desired?

2g Basic

Press the Light Switch ON. Does the LED

Operational light illuminate the interior of the cabinet?

Checks

Does the Blower operate with the Blower

Switch ON and the sash open?

Y N Y N

If equipped, does the UV lamp, mounted in Y N the upper-rear of the interior, operate when the UV Lamp Switch is turned ON and the N/A sash is fully closed?

6

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

Does the sash rise smoothly to the appropriate height for the model indicated on the ID Plate?

Y N

Series 30238, 30248, 30348, 30258, 30268 & 30368 should have an 8-inch sash opening.

Series 30231, 30241, 30251 & 30261 should have a 10-inch sash opening.

Series 30232, 30242, 30252 & 30262 should have a 12-inch sash opening.

Do the audible and visual alarms indicate

Y N

when the sash has been raised/lowered 1″

above or below the indicated 8, 10 or 12-

inch positioning mark?

Does the Alarm Mute button stop the audible alarm for approximately 5 minutes when pressed?

Y N

Has the BSC been posted with warnings to Y N not be used until certified?

7

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

B. Operational Qualification

Step 1 1a
2 2a
3 3a 3b

Description Certification Initial Certification
Training User Training
Cleaning Exterior Cleaning Interior Cleaning

Specification or Acceptance Criteria
Prior to use, has a qualified certifier tested the cabinet to the NSF 49 standard the cabinet was listed under? Has the certifier labeled the BSC with the successful certification date?
Certification should be done at least annually. Has the next required certification been added to your quality system’s preventive maintenance or certification schedule?
Have all users been properly trained on the safety, theory of operation and limitations of the BSC?
Do all users understand techniques for: Cleaning & disinfection of the cabinet’s interior Loading supplies and equipment Avoiding cross contamination Not disturbing the laminar flow Spill control and clean up Shutting down the cabinet If equipped, use of the UV lamp?
Has the exterior of cabinet been cleaned of dust that accumulated throughout installation?
Have the BSCs interior surfaces been cleaned and disinfected appropriately for the work that is about to be performed in it?

Result YES NO
Y N Y N
Y N Y N
Y N Y N

8

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

Inspect the towel catch screen located in

Y N

the rear under the worksurface for any

foreign debris, remove any foreign objects

from the towel catch.

4

Alarm

Operation

4a Sash Position Alarm

Raise the sash above or below the
operational sash height of 8, 10 or 12inches. Does the BSC signal a “Alarm Sash Height” message?

Y N

4b Airflow Alert Using a notebook or cardboard block the

Y N

large series of airflow slots on the air inlet

grille. Does the BSC:

The internal motor/blower audibly

increase speed?

Signal an “Alert ­ Airflow” message?

4c Airflow

If the BSC has been equipped with the

Y N

Monitor

optional airflow sensor ­ raise the exhaust

(Optional on HEPA filter cover or block the black airflow

A2)

sensor outlet. Does the airflow value drop?

4d Canopy

If the BSC has been equipped with the

Y N

Alarm

optional VentusTM II Canopy Connection ­

(Optional ­ Raise the front exhaust flap on the canopy

A2 only)

until the side (intake) flap closes, does the

BSC signal an “Alarm ­ Canopy”

message?

9

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A
C. Performance Qualification
NOTE: This Performance Qualification section is only a recommendation of some basic items to consider for your protocol. Your protocol should include tests and inspections that are pertinent to the applications performed within the equipment.
Step Description Suggested Criteria

1

Periodic

Certification

1a Cabinet

Certification should be done at a minimum

Performance annually. A qualified certifier can verify the

cabinet’s performance.

Is the BSCs current certification

within the acceptable timeframe set

by your organization?

Has there been a procedure

established if a cabinet is found to

have exceeded its certification due

date?

Is the next required certification noted in
your quality system’s preventive maintenance or certification schedule?

2

Maintenance

2a UV Lamp

If equipped, the UV lamp should be replaced at least annually or every 6,000hours to remain effective. The UV Maintenance Timer can track the hours of operation and supply an alert.

2b Towel Catch The towel catch screen located in the rear under the worksurface should be checked for any foreign debris when the cabinet is cleaned.

2c LED Light

Regular maintenance should ensure that the LED Light is operating properly.

2d BSC Sump Regularly clean and maintain the sump located underneath the removable work surface. If installed, clean the drain valve.

10

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

2e Prefilter (optional)

Some cabinets have a prefilter installed with the towel catch. If desired, inspect the condition of the prefilter, clean or replace regularly.

2f Postfilter (optional)

Some cabinets that exhaust back into the room may have an activated carbon postfilter. If equipped, replace filter regularly to control odors.

2g Canopy (A2 For Class II, Type A2 BSCs connected to

only)

exhaust through a canopy: the alarm

(optional)

function of the canopy should be exercised

regularly for proper operation.

11

Labconco Logic Series BSCs IQ/OQ/PQ Protocol #1058606 Revision A

D. Summary
Labconco Logic Series BSC IQ/OQ/PQ Document 1058606 Revision A Equipment Location _________________________________________________ Serial No. __________________________ Model No.__________________

User Protocol _________________ Revision (or Date published) __________

Contact (print name):____________________________________________

Title: __________________________________________________________

Review the “Response” columns for answers of “NO.” Use the area below to describe the deficiency or unacceptable results. Those deficiencies are to be
followed with an instruction for “Corrective Actions.” Once acceptable results are obtained, the deficiency is “accepted” by initialing the Corrective Action.

Step

Deficiency followed by Corrective Action

Initial

12

Introduction

Congratulations on the purchase of a Labconco Purifier Logic Series Biosafety Cabinet. The Biosafety Cabinet is designed to protect you, the product and the laboratory environment from biohazardous aerosols. The Logic Series Cabinet is the result of years of experience in manufacturing biohazard cabinetry, and users like you suggested many of its features to us. The Biosafety Cabinet offers many unique features to enhance safety, performance and ergonomics. To take full advantage of them, please acquaint yourself with this manual and keep it handy for future reference. If you are unfamiliar with how biosafety cabinets operate, please review
Chapter 4: Performance Features and Safety Precautions before you begin working in the cabinet. Even if you are an experienced biosafety cabinet user, please review Chapter 5: Using the Cabinet; it describes the Biosafety Cabinet’s features so that you can use it efficiently.
This manual and other technical information is available in PDF format at our website: www.labconco.com.

Prerequisites

Before you install the Biosafety Cabinet, you need to prepare the site for installation. Examine the location where you intend to install the cabinet.
You must be certain that the area is level and of solid construction. In addition, a dedicated source of electrical power must be located near the installation site.

Carefully read this chapter to learn:

• Location requirements.
• Electrical power requirements.
• Exhaust requirements.
• Service utility requirements.
• Space requirements.

Refer to Appendix C: Specifications, for complete biosafety cabinet electrical and environmental conditions, specifications and requirements.

Space Requirements
The dimensions for the Logic A2 Biosafety Cabinets are shown in Appendix B: Dimensions.

Clearance
A minimum clearance of at least 6 inches (150 mm) is suggested on the top and both sides of the cabinet for service.

Location Requirements

Note: The Biosafety Cabinet should be located away from traffic patterns, doors, fans, ventilation registers, fume hoods and any other air-handling devices that could disrupt its airflow patterns. All windows in the room should remain closed. Figure 2-1 shows the preferred location for the Biosafety Cabinet.

Exhaust Requirements

If you intend to connect the Biosafety Cabinet to the optional Canopy Connection Kit, first examine the location to ensure that it accommodates the cabinet’s exhaust duct. The area directly above the cabinet’s exhaust port should be clear of structural elements, water and utility lines, or other fixed obstructions. There should be enough clearance to accommodate a 10-inch diameter duct. Avoid cabinet locations that require an elbow directly above the cabinet’s exhaust connection or an excessive number of elbows in the exhaust system. For further information about the cabinet’s exhaust system requirements, please refer to Chapter 3: Getting Started.

Electrical Requirements
The different Biosafety Cabinet models have the following electrical requirements:

All Biosafety Cabinets with model numbers ending in –00 to –09 are designed for operation at 115 volts 60 Hz, alternating current. Biosafety
Cabinets with model numbers ending in –20 to –29 are designed for operation at 230 +/- 20 volts, 50/60 Hz alternating current.
Note: A dedicated outlet with a circuit breaker rated at 20 amps should be located as close as possible to the right rear side of the cabinet, at a height even with, or higher than, the top of the bench or stand.
Note: On 115 VAC models, both electrical outlets are protected by a ground fault interrupter circuit (GFIC). Labconco does not recommend plugging the Biosafety Cabinet into a GFIC outlet.

Service Line Requirements

All utility service lines should be ¼ inch O.D., brass, copper, or stainless steel, and equipped with an easily accessible shut-off valve. If the service line pressure exceeds 100 PSI, it must be equipped with a pressure regulator to reduce the line pressure.
Note: The use of flammable gases or solvents should be avoided in the Biosafety Cabinet. Open flame in the cabinet will disrupt the laminar airflow in the cabinet and may damage the HEPA filters. Flammable gases or solvents may reach explosive concentrations in the cabinet or ductwork. If you feel that the procedure requires the use of an open flame or flammable materials, contact the institution’s safety office.
The use of air or gases under high pressure should be avoided as they may seriously disrupt the airflow patterns in the cabinet.

Getting Started

Now that the installation is properly prepared, you are ready to inspect, install, and certify the Purifier Biosafety Cabinet. This chapter covers how to:

• Unpack and move the Biosafety Cabinet.
• Install the cabinet.
• Connect the electrical supply source.
• Connect the service lines.
• Connect to an exhaust system (optional).
• Arrange certification of the Biosafety Cabinet.

Tools required for installation the Biosafety Cabinet include two 1/2″ wrenches, a flat-blade screwdriver, a #2 Phillips screwdriver, and a carpenter’s level.

Note: The Biosafety Cabinet models weigh between 400–700 lbs. (182-318 kg). The shipping pallet allows for lifting with a mechanical lift truck or floor jack. If you must lift the product manually, use at least six (6) persons and follow safe-lifting guidelines.
Note: The side panels must be removed to access the fasteners that secure the Biosafety Cabinet to the pallet. DO NOT ATTEMPT TO LIFT THE BIOSAFETY CABINET BY THE SIDE PANELS; DAMAGE WILL OCCUR.

Unpacking the Biosafety Cabinet

Carefully remove the outer carton and inspect the cabinet for damage that may have occurred in transit. If the Biosafety Cabinet is damaged, notify the delivery carrier immediately and retain the entire shipment intact for inspection by the carrier.
Note: United States Interstate Commerce Commission rules require that claims be filed with the delivery carrier within fifteen (15) days of delivery.
Do not return goods without the prior authorization of Labconco.
Unauthorized returns will not be accepted.
If the cabinet was damaged in transit, you must file a claim directly with the freight carrier. Labconco Corporation and its dealers are not responsible for shipping damages.
Do not discard the carton or packing material for the Biosafety Cabinet until all of the components have been checked, installed and tested.
The cabinet is secured to the pallet in two places on each side. To access the nuts and bolts, remove the side panels by removing and keeping the two Phillips screws on both panels. Swing the front of each panel away from the Cabinet, and lift it straight up to remove the panel from the cabinet.

The following are located in a box underneath the work surface:

• User’s Manual
• Drain Valve Assembly and fasteners
• Power Cord
• Product Registration Card

If you did not receive one or more of the components listed for the cabinet, or if any of the components are damaged, contact Labconco Corporation immediately for further instructions.

Moving the Cabinet
Move the cabinet, attached to its pallet, by using a floor jack, or a furniture dolly underneath the unit. DO NOT move the cabinet by tilting it onto a hand truck.

Preparing the Biosafety Cabinet for Operation

Installation instructions for the cabinet (Labconco P/N 1056801) are attached to the sash of the Biosafety Cabinet. If these instructions are missing or unclear, contact Product Service at 800-821-5525 or 816-333-8811.

Installing the Biosafety Cabinet on an Existing
Work Surface

Note: The Biosafety Cabinet is very top heavy. Use caution when lifting or moving it.
When installing the Biosafety Cabinet onto an existing work surface or benchtop, ensure that the structure can safely support the combined weight of the cabinet and any related equipment. The work surface should be at least as wide as the Cabinet and 31 inches (787 mm) deep to properly support the unit.
A hole or notch may be cut in the supporting surface in the right front corner to accommodate the optional drain valve.

Installing the Cabinet on a Labconco Base Stand
Labconco offers accessory Base Stands in a variety of configurations to suit the particular needs. Stands can be ordered with adjustable telescoping legs or with a manually or electrically adjustable hydraulic lift.

Telescoping Base Stands
These stands are available with either fixed feet or casters. Adjust the leg height before installing the cabinet on top of the stand. The height can be set in 1-inch intervals between 27.5 to 34.5 inches (699 to 876 mm), providing a Cabinet work surface height from 30.0 to 37.0 inches (762 to 940 mm). The Base Stands for each width Cabinet are listed in Table 3-1 below.

Table 3-1

1. Before positioning the Telescoping Base Stand in its final location, adjust the height. A plastic bag containing the mounting bolts for the Biosafety Cabinet is shipped with the base stand. Remove and save it.
2. Select the height of the stand and slide four (4) leg extensions into base stand corner posts and attach with 2 ¼ inch long bolt, flatwasher, lockwasher and nut. Ensure that the same height hole is selected for each leg. Tighten the leg bolts securely. See Figure 3-1.

3. CAUTION: Only lift and support the weight of the cabinet at the stainless steel sides and back. Damage will occur if lifted or supported on the front edge. Move the base stand into its final location. Using a carpenter’s level, adjust each leveling foot until the stand is level in both planes as shown in Figure 3-2. You are now ready to lift the Biosafety Cabinet onto its stand.

Manual or Electric Hydraulic Lift Base Stands

These base stands offer infinitely adjustable height between 25.5 and 33.5 inches (648 to 851 mm), giving a Cabinet work surface height of 28.0 to 36.0 inches. The height is adjusted either by a manual (hand crank) or electric pump that drives hydraulic rams in the legs of the stands. All of the hydraulic stands are equipped with fixed feet, but can be converted to caster wheels with the addition of Caster Kit #3784000. The Base Stands for each Cabinet model is listed in Table 3-2 below.

Table 3-2

Note: When installing the Cabinet on the hydraulic lift base stand, ensure that the hydraulic lines and the electrical cord are clear of any obstructions before installing the cabinet on the stand or operating the lift system.

Connecting the Biosafety Cabinet to Utility Service Lines
The service lines (if any) should be connected to the tube fitting(s) on the outside of the liner wall as shown in Figure 3-3. To install the tubing, follow these steps:

1. Ensure that the tubing is ¼ inch O.D., soft metal, and that the end has been completely deburred.
2. Route the tubing from the rear of the cabinet, ensuring that it will line up with the slot in the back of the side panel. The slot is located from 8 ¾ to 11 ¼ inches (222 to 288 mm) from the bottom of the cabinet.
Note: Make sure that the tube routing will not contact any electrical wires. DO NOT loop service line tubing within the side panels of the Cabinet.
3. Make sure that the nut on the tube fitting is loose, but do not remove it. Look inside the fitting to make sure the tube ferrule is there.
4. Push the tube into the fitting until it is properly seated. The tube will go approximately ¾ inch (19 mm) into the fitting.
5. Tighten the tube fitting nut hand tight and then, using a 7/16-inch wrench, tighten it at least ¾ turn more.
6. Close the service valve in the Biosafety Cabinet and then slowly open the shutoff valve on the service valve. Test all fittings for leakage. Tighten the tube nut slightly if needed.

Performance Features and Safety Precautions

All Purifier Series Logic Biosafety Cabinets operate using the following principles:

• Filtration and retention of particulates by High Efficiency Particulate Air (HEPA) filter(s)
• Laminar airflow
• Directional airflow

The major components in a Biosafety Cabinet are:

• The HEPA filter(s) or optional ULPA filters
• The motor/blower to force air through the Cabinet
• Cabinet air intakes (grilles), ductwork and air balance controls

HEPA Filters

HEPA filters are disposable, dry-type particulate filters. The filter material ormedia is typically made of borosilicate microfibers formed into a thin sheet, in a process similar to the production of paper. This sheet is folded, or pleated to increase its surface area. The pleats are held in place by aluminum diffusers or by beads of glue that add rigidity to the media pack. The pack is then set into a frame, and sealed as shown in Figure 4-1.
The HEPA filter manufacturer establishes the efficiency of the filter by challenging it with an aerosol of known particle size. The number of particles that penetrate the filter are quantified, and this establishes the efficiency of the filter. Thus, the filters used in the Logic Series Cabinets are at least 99.99% efficient in removing particles 0.3 micron.

Note: The HEPA filter media is very fragile. DO NOT touch the media. If you think the media of a HEPA filter is damaged, DO NOT USE THE CABINET. Have the HEPA filter integrity tested by a certifier before using the cabinet.
Note: HEPA Filters are only effective against particulate material. Gases will pass through the filter.

Using the Cabinet

System Reset Switch
The Biosafety Cabinet has a system reset switch for resetting its microprocessors. The switch is located on the front of the electronics module, on top of the Cabinet, as shown in Figure 5-1. Ensure that the switch is in the “ON” (up) position before attempting to operate the Cabinet.

Information Center
The Information Center is an LCD display located on the right side wall at eye level. The center’s display is divided into three separate areas, as shown in Figure 5-2, below. The display will turn itself off one minute after the blower is turned off or the sash is closed.

Status Area
The Status Area displays the system’s condition during operation. This line can display any of the following messages:
Blower Off
The cabinet blower is shut off.
Please Wait
For three minutes after the cabinet blower is turned on, the display will say this, to allow the cabinet to reach proper operating conditions.
OK
The motor is operating properly, and the sash is not open too far.
Night-Smart™
If the Night-Smart mode is selected, as outlined later in the chapter, this message will appear for one minute after the sash is closed, and then the display will automatically shut off.
Sash is too high
The sash is open too far for safe operation.
Airflow Alert
The airflow patterns in the cabinet have changed, resulting in a sudden change in the motor speed. This is most likely due to a blockage of the grille or the exhaust filter outlet. It may also be caused by removal of the work surface while the cabinet is in operation.
System Error
The motor and display circuit board are not communicating properly. DO NOT USE THE CABINET UNTIL THE PROBLEM HAS BEEN CORRECTED.

Data Area

The Data Area displays the Filter Gauge. This bar graph displays the percentof remaining filter life. When the cabinet is new, or after the HEPA filters are replaced, the gauge will be “full”, or display approximately 100%. As the filters load, or if the grille or exhaust discharge are blocked, the bar graph will show a reduced filter life.
The graph is user-selectable as a bar graph with percentage displayed, a bar graph only, or a semi-circular graph showing filter life remaining.
Various factors such as temporary obstructions to airflow, temperature and barometric pressure can cause the displayed percentage to vary slightly.
Ignore short term changes in the Filer Gauge’s value. As the Filter Gauge approaches 20% remaining capacity, consider having the cabinet filter replaced.
When the optional airflow sensor is installed and calibrated, the inflow and calculated downflow velocities are also displayed during operation.

Icon Area
The Icon Area displays icons for those features selected or in operation. The Icons are:

Documents / Resources

LABCONCO Logic Series Class II Biological Safety Cabinets [pdf] Instructions 30231xxx2, 30238xxx2, 30232xxx2, 30241xxx2, 30248xxx2, 30242xxx2, 30348xxx2, 30251xxx2, 30258xxx2, 30252xxx2, 30261xxx2, 30268xxx2, 30262xxx2, 30368xxx2, Logic Series Class II Biological Safety Cabinets, Logic Series, Class II Biological Safety Cabinets, Biological Safety Cabinets, Safety Cabinets, Cabinets

References

• User Manual