Sistemụ nnyefe insulin akpaghị aka

Nkọwapụta ngwaahịa

• Aha ngwaahịa: Sistemụ nnyefe insulin akpaghị aka Tubeless
• Ụdị: Ngwa ahụike
• Atụmatụ: Tubeless, n'ahụ, ebumnuche glycemic nwere ike ịhazi ya
• Otu afọ: Ụmụaka dị obere nwere ụdị ọrịa shuga 1
• Ogologo oge: usoro ọgwụgwọ ọkọlọtọ ụbọchị 14 sochiri usoro enyemaka enyemaka ọnwa 3 yana sistemụ Omnipod 5.

Ozi nchekwa

• Ebumnuche ụlọọgwụ: Nyochaa nchekwa na ịdị irè nke Omnipod® 5 Automated Insulin Delivery (AID) Sistemu, nke mbụ na-enweghị tube na-enweghị, sistemu AID nke anụ ahụ nwere ebumnuche glycemic nwere ike ịhazi ya n'ime ụmụaka nwere ụdị ọrịa shuga 1.
• Isi njedebe:
  • HbA1c na njedebe nke usoro AID ma e jiri ya tụnyere ntọala
  • Oge dị na nso nso 3.9-10.0 mmol / L n'oge usoro AID ma e jiri ya tụnyere usoro ọgwụgwọ ọkọlọtọ (ST).
  • Ọnụọgụ nke hypoglycemia siri ike ma ọ bụ ketoacidosis nke ọrịa mamịrị (DKA)
• Ebe njedebe nke abụọ gbakwunyere oge pasentị na ọkwa glucose <3.9 mmol/L na> 10.0 mmol / L n'oge usoro AID ma e jiri ya tụnyere usoro ST.

Ntuziaka maka ojiji

Nhazi ọmụmụ

• Otu-ogwe aka, multicentre, ụlọ ọgwụ ọmụmụ:
  • Oge 14-ụbọchị ST
  • Usoro enyemaka ọnwa 3 nwere sistemụ Omnipod 5
• Ọnweghị ihe achọrọ maka oke opekata mpe ahụ ma ọ bụ ngụkọta insulin kwa ụbọchị

Ndị sonyere ọmụmụ ihe

• 80 Ụmụaka nwere ụdị ọrịa shuga 1: Afọ 2.0-5.9, yana nkwenye mara ọkwa nke onye nlekọta.
• HbA1c <10% (86 mmol/mol) na nyocha
• Iji mgbapụta mbụ ma ọ bụ CGM achọghị
• Usoro mwepu: akụkọ ihe mere eme nke DKA ma ọ bụ hypoglycemia siri ike n'ime ọnwa 6 gara aga

• p <0.0001.
• p=0.02.
• A na-eji data ndabere na nsochi mee ihe maka isi njedebe HbA1c. Data egosiri maka usoro ọgwụgwọ ọkọlọtọ yana usoro AID. Egosiri data dị ka etiti maka oge <3.9 mmol/L yana pụtara maka nsonaazụ ndị ọzọ niile.
• Enweghị ihe ngosi nke nnukwu hypoglycemia ma ọ bụ DKA n'oge AID.

Atụmatụ

Isi ihe ọmụmụ

• E jiri ya tụnyere usoro ST, usoro Omnipod 5 wedara HbA1c, mụbaa TIR, ma belata hypoglycemia na ụmụaka nwere ụdị ọrịa shuga 1.
• Oge na nsoro abalị (00:00 - 06:00 h) gbagoro site na 58.2% (ST phase) ruo 81.0% (Omnipod 5 phase)
• Enweghị ihe ngosi nke nnukwu hypoglycemia ma ọ bụ DKA n'oge AID
• Ọnụ ọgụgụ ụmụaka na-ezute ebumnuche nkwenye maka HbA1c, <7.0% (53 mmol/mol), mụbara site na 31% site na usoro ọgwụgwọ a na-emebu ruo 54% mgbe ejirichara sistemụ Omnipod 5.
• Ọnụ ọgụgụ ụmụaka na-ezute ebumnuche maka> 70% Oge na oke gbagoro okpukpu 2.5 site na 17% site na usoro ọgwụgwọ a na-emebu ruo 44% mgbe ejirichara sistemụ Omnipod 5.
• Oge etiti na ọnọdụ akpaaka n'oge usoro Omnipod 5 bụ 97.8%
• Enwere ike iji Sistemu Omnipod 5 n'enweghị nsogbu yana nke ọma n'ime ụmụaka nwere ụdị ọrịa shuga 1

Enyerela nchịkọta a dịka akụkụ nke Omnipod Academy, ọrụ nkuzi nke Insulet nyere ndị ọkachamara nlekọta ahụike.

Nkọwa ngwaahịa

Ntụaka 1. E si na; Sherr JL, et al. Nchekwa yana nsonaazụ glycemic site na sistemụ nnyefe insulin akpaghị aka na Tubeless na ụmụaka nwere ụdị ọrịa shuga 1: Clinical Multicenter nke otu ogwe aka.

Nnwale. Nlekọta ọrịa shuga 2022; 45:1907-1910.

• N'ime ọmụmụ ụlọ ọgwụ ọnwa 3, a kọrọ akụkọ 0 nke hypoglycemia siri ike na ọrịa 0 nke ketoacidosis mamịrị (DKA) na ụmụaka n'oge ojiji sistemụ Omnipod 5.
• Omnipod 5 Automated Insulin Delivery System bụ otu usoro nnyefe insulin nke ezubere iji nyefee insulin U-100 n'okpuru anụ ahụ maka njikwa ụdị ọrịa shuga 1 n'ime ndị gbara afọ 2 na karịa chọrọ insulin. Ezubere Sistemu Omnipod 5 maka iji otu onye ọrịa mee ihe.
• Ezubere Sistemu Omnipod 5 ka ọ rụọ ọrụ dị ka usoro nnyefe insulin na-akpaghị aka mgbe ejiri ya na ndị na-ahụ maka glucose na-aga n'ihu (CGM) dakọtara. Mgbe ọ nọ na ọnọdụ akpaaka, emebere sistemụ Omnipod 5 iji nyere ndị nwere ụdị ọrịa shuga 1 aka inweta ebumnuche glycemic nke ndị na-ahụ maka ahụike ha setịpụrụ. Ezubere ya iji gbanwee (ịbawanye, ibelata, ma ọ bụ kwụsịtụ) nnyefe insulin ka ọ rụọ ọrụ n'ime ụkpụrụ ọnụ ụzọ akọwapụtagoro site na iji ụkpụrụ CGM dị ugbu a na nke amụma buru amụma iji nọgide na-enwe glucose ọbara na ọkwa glucose dị iche iche, si otú a na-ebelata mgbanwe glucose. Mbelata nke mgbanwe a bu n'obi bute mbelata ugboro ole, ogo na ogologo oge nke hyperglycemia na hypoglycemia.
• Sistemụ Omnipod 5 nwekwara ike ịrụ ọrụ n'ụdị ntuziaka na-ebuga insulin n'ogo atọrọ ma ọ bụ ejiri aka dozie ya.

Egosiputara sistemu Omnipod 5 maka iji NovoLog®/NovoRapid®, Humalog®/Liprolog®, Trurapi®/Truvelog®/Insulin aspart Sanofi®, Kirsty®, na Admelog®/Insulin lispro Sanofi U-100 insulin. Ịdọ aka ná ntị:

• E kwesịghị iji teknụzụ SmartAdjust™ onye ọ bụla na-erubeghị afọ abụọ.
• Ndị mmadụ na-achọ ihe na-erughị nkeji ise nke insulin ekwesịghị iji teknụzụ SmartAdjust™ mee ihe kwa ụbọchị n'ihi na enyochabeghị nchekwa teknụzụ n'ime ndị a.
• A naghị atụ aro Sistemụ Omnipod 5 maka ndị na-enweghị ike nyochaa glucose dị ka ndị na-ahụ maka ahụike na-atụ aro, na-enweghị ike ịnọgide na-enwe kọntaktị na onye na-ahụ maka ahụike ha, na-enweghị ike iji Omnipod 5 System dị ka ntuziaka si dị, na-ewere hydroxyurea n'ihi na ọ nwere ike iduga n'ebuli CGM dị elu na-ezighị ezi ma na-ebute nnyefe insulin nke nwere ike ime ka ọ ghara inwe mmetụta hypoglycemic zuru oke, ma ọ bụ na-enweghị ike ịnụ ihe ọ bụla. Sistemụ Omnipod 5, gụnyere ọkwa, mkpu na ihe ncheta. Ngwa akụrụngwa gụnyere Pod, CGM transmitter, na CGM sensọ ga-ewepụrịrị tupu Magnetic Resonance Imaging (MRI), Computed Tomography (CT) scan, ma ọ bụ ọgwụgwọ diathermy. Tụkwasị na nke ahụ, a ga-etinye onye nchịkwa na smartphone n'èzí nke ụlọ usoro. Ngosipụta na MRI, CT, ma ọ bụ ọgwụgwọ diathermy nwere ike imebi ihe ndị ahụ.
• Rụtụ aka na ntuziaka onye ọrụ Sistemụ Nnyefe Insulin Automated 5 maka ndepụta nkọwa zuru oke, mgbochi, ịdọ aka na ntị, ịdọ aka na ntị na ntuziaka. Ntuziaka dị site na ịkpọ anyị na 1-855-POD-INFO (1-855-763-4636) ma ọ bụ site na ịga na nke anyị websaịtị na omnipod.com
• ©2025 Insulet Corporation. Omnipod na akara Omnipod bụ ụghalaahịa ma ọ bụ ụghalaahịa edenyere n'akwụkwọ ikikere nke Insulet Corporation na United States of America na ikike ndị ọzọ dị iche iche. Ikike niile echekwabara. Ighalaahịa ndị ọzọ niile bụ ihe onwunwe nke ndị nwe ha. Ojiji ụghalaahia nke ndị ọzọ anaghị abụ nkwado ma ọ bụ gosi mmekọrịta ma ọ bụ mmekọ ọzọ.
• Ụlọ ọrụ Insulet, 1540 Cornwall Rd, Suite 201, Oakville, NA L6J 7W5. INS-OHS-12-2024-00217 V1.0

Ajụjụ a na-ajụkarị

• Ajụjụ: Onye kwesịrị iji sistemu nnyefe insulin akpaghị aka nke Tubeless a?
  • A: Emebere usoro a maka ụmụaka nwere ụdị ọrịa shuga 1 n'okpuru nlekọta nke ndị ọkachamara ahụike.
• Ajụjụ: Gịnị bụ isi njedebe nke iji usoro a?
  • A: Isi njedebe ndị bụ isi gụnyere ịlele ọkwa HbA1c na njedebe nke usoro AID ma e jiri ya tụnyere ntọala, yana atụnyere ọnụọgụ nke nnukwu hypoglycemia ma ọ bụ ketoacidosis na-arịa ọrịa shuga na ọgwụgwọ ọkọlọtọ.
• Ajụjụ: Ogologo oge ole ka oge ọmụmụ maka iji ngwaọrụ a dị?
  • A: Ọmụmụ ihe ahụ gụnyere usoro ọgwụgwọ ọkọlọtọ ụbọchị 14 na-esote usoro enyemaka enyemaka ọnwa 3 na sistemụ Omnipod 5.

Akwụkwọ / akụrụngwa

Sistemụ nnyefe insulin akpaghị aka [pdf] Akwụkwọ ntuziaka onye nwe Sistemụ nnyefe insulin na-akpaghị aka, sistemụ nnyefe insulin, sistemụ nnyefe

Ntụaka

• Akwụkwọ ntuziaka onye ọrụ