hygiena BAX System Q7 Software Upgrade User Guide

BAX System Q7 Software Upgrade

Specifications:

  • Software Version: Release v5.0.1.16813
  • Additional Assays: Seven foodproof assays with experimental
    analysis files
  • Product Numbers:
    • KIT230088
    • KIT230092
    • KIT230129
    • KIT230099
    • KIT230106
    • KIT230103
    • KIT230077
    • KIT230145
    • KIT230137
    • KIT230119
    • KIT230134
    • KIT230131
    • KIT230117
    • KIT230112
  • Assay Analysis Files: Available for all assays (BAX, foodproof,
    microproof)

Product Usage Instructions:

Viewing Data from Experimental Analysis Files:

All assays with experimental analysis files require visual
verification of the graphs for result interpretation.

Setting Analysis Files:

To set the analysis file to Experimental for targets without
verified analysis files:

  1. Go to Operation Analysis Settings.
  2. Select Experimental as the analysis file (Algorithm)
    setting.

Software Upgrade Instructions:

Required Prerequisites:
  • Ensure Regional Settings are in English.
  • Turn off Core Isolation setting in Windows security
    settings.
  • Grant Read/Write Permissions for specific file locations.
  • Set Power and Sleep Settings to Never.
  • Enable notification before restarting after a Windows
    upgrade.
Calibration Kit:

If running foodproof/microproof assays using HEX dye, obtain the
HEX Calibration Kit (Product No.: KIT230340) from Hygiena. This
calibration plate is a stand-alone product and not included in
other kits.

Calibration Storage and Software Removal:
  1. Back up the system’s calibration file by exporting it via
    Operations > BAX Maintenance > Export Calibration.
  2. Uninstall the previous version of the BAX Q7 application by
    navigating to Windows Settings, selecting Apps, clicking on BAX
    System Q7, and agreeing to uninstall.
  3. If updating from versions 4.21 or 4.22, MATLAB removal is not
    required. For updates from earlier versions, uninstall MATLAB as
    well.

FAQ:

Q: Are the new foodproof assays in version 5.0 compatible with
previous software settings?

A: If you are using version 4.22 to run foodproof assays, your
selected settings will remain the same. Only the new foodproof
assays in version 5.0 will need adjustments to your
preferences.

Q: How can I access and set the analysis files for experimental
interpretation?

A: To access and set the analysis files to Experimental for
targets without verified files, go to Operation Analysis Settings
and select Experimental as the setting.

Q: Is the HEX Calibration Kit included in the standard
calibration kits?

A: No, the HEX Calibration Kit (Product No.: KIT230340) is a
separate stand-alone product available for purchase from Hygiena
for use in foodproof/microproof assays utilizing the HEX dye.

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BAX® System Q7 Version 5.0.1.16813 Features and Instructions

BAX System Q7 software release v 5.0 contains several user interface features, new target options, and error logging improvements. We strongly recommend that you install the latest version as soon as possible for optimal performance. Please read all instructions thoroughly and ensure all required prerequisites are confirmed prior to beginning the installation of the software update. If you currently have a Windows 7 computer system, please contact diagnostics.support@hygiena.com or your local Hygiena® representative for Windows 10 upgrade support. This release is ONLY applicable for Windows 10 and Windows 11 Operating systems.
Software Assay Updates for Release v5.0.1.16813 There are no changes to the analysis for BAX assays (vs. versions 4.21 and 4.22)

Seven additional foodproof assays with experimental analysis files for assistance with result interpretation:

Product Name

Product Number

foodproof® Listeria Genus Detection LyoKit

KIT230088

foodproof® Listeria monocytogenes Detection LyoKit

KIT230092

foodproof® Listeria plus L. monocytogenes Detection LyoKit

KIT230129

foodproof® Salmonella Detection LyoKit

KIT230099

foodproof® Salmonella Enteritidis & Typhimurium Detection LyoKit

KIT230106

foodproof® Staphylococcus Detection LyoKit

KIT230103

foodproof® STEC Screening LyoKit

KIT230077

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foodproof/microproof® assays with improved experimental analysis files for assistance with result interpretation:

Product Name foodproof® Aspergillus Detection LyoKit (Real-time only) foodproof® Enterobacteriaceae plus Salmonella Detection LyoKit microproof® Legionella Quantification LyoKit foodproof® Salmonella Genus plus Enteritidis & Typhimurium Detection LyoKit foodproof® Salmonella plus Cronobacter Detection LyoKit foodproof® Vibrio Detection LyoKit (Real-time only) foodproof® Yeast and Mold Quantification LyoKit

Product Number KIT230145 KIT230137 KIT230119 KIT230134
KIT230131 KIT230117 KIT230112

Important Note: All foodproof and microproof assays with experimental kit analysis files are designed to assist in result interpretation but require visual verification of the graphs.

Additional information for viewing data from experimental analysis files:
Analysis files are now available for all assays (i.e., BAX, foodproof, microproof). By default, all assays with experimental analysis files will have analysis files set to “None”. The user can go to Operation
Analysis Settings to set the analysis file (Algorithm) to “Experimental” for targets that do not have
verified analysis files. This setting enables improved assistance with results interpretation.

. All verified assays will have only one setting displayed as “Certified.” If you are using 4.22 to run foodproof assays, your selected setting will remain the same. Only the
new foodproof assays in 5.0 will need to be adjusted to your preference.

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Software Feature Updates for Release v5.0.1.16813 Users are now able to register the Q7 to the SureTrend® application available on the cloud. Ability to review data online both graphically and by result status with the SureTrend software. To use this feature, you must register a SureTrend account https://suretrend.hygiena.com/Register Users can now export comma-delimited text files (.csv) There is a one-step compressed log file export Software will now check that the correct calibration file is imported for the instrument in the case of equipment replacement by loaners or service units. Each Q7 has a unique calibration file and should only be used with that Q7. Every calibration file generated with software version 4.0 and higher collects the serial number of the camera of
the Q7 and the serial number of the thermal block. This information is stored in the calibration file. When a calibration file is imported, the application will compare the serial numbers in the calibration file to the serial numbers of the instrument on which you are importing. If the serial numbers don’t match, the following pop-up message will appear. If this message appears, locate the correct calibration file (if it’s a recent replacement unit, it can be found in the sleeve on the back of the unit – or – contact Hygiena to request the correct file). If the correct file cannot be located, calibrate the instrument as instructed in the BAX Q7 User Guide.
If “Yes” is clicked in the pop-up message above, a secondary message will appear

If `Continue’ is selected, the calibration will import, and no additional warnings or notifications will appear.

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Software Upgrade Instructions:
1. Required Prerequisites: Regional Settings are in English Core Isolation setting should be turned off in Windows security settings
Read/Write Permissions for the below file locations for all users C:Program FilesMATLAB C:Program Files (x86)BAX C:ProgramDataBAX Q7 System All Power and Sleep Settings are set to Never. Notify before restarting after a Windows upgrade is enabled
Obtain the HEX Calibration Kit (Product No.: KIT230340) from Hygiena if you plan to run foodproof/microproof assays that utilize the HEX dye (see kit instructions). This additional calibration plate is a stand-alone product and is not included with other calibration kits. Please visit the Contact Us page for ordering and technical support.
2. Calibration storage and removal of current software: Back up the system’s calibration file. Select Operations > BAX Maintenance > Export Calibration from the menu bar. Navigate to a new folder in which to store the backup file and click Save. Name the calibration file (example: Q7Cal_date.bqc).
Uninstall the previous version of the BAX Q7 application. Navigate to Windows Settings and select Apps.

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Click on BAX System Q7, select Uninstall, and agree (click Yes) on the next window to initiate removal.

If updating from 4.21 or 4.22, removal of MATLAB is not required. If updating from any previous versions, click on the MATLAB application, select Uninstall, and click Agree on the next window (this may take several minutes).

Restart the computer BEFORE continuing to step 3.
3. Download 5.0.1.16813 software by clicking this link or the button from the BAX Q7 Page. Transfer the download to a memory/USB stick if the computer doesn’t have internet access. Click on the Q7 5.0.1.16813 icon and the program will automatically start execution of installation.
A Windows protect screen may pop up. Select More Info, then select Run anyway. On the next pop-up, select Yes to allow installation to begin

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4. There may be some prerequisites that need to be installed first to prepare your computer for the BAX application installation.
If you see these, you may have to restart multiple times to get the prerequisites installed before MATLAB Runtime can install
Checking memory integrity and Correct regional settings (not shown) are the first two prerequisites that need to be addressed or the Application will not install successfully. In case this install error occurs: VCRUNTIME140.dll was not found (shown below). Please download and install the patch: vc_redist.x64.exe from
https://www.microsoft.com/en-us/download/details.aspx?id=52685. The installation will end when you click OK.

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5. MATLAB updates will be installed (after prerequisites). Follow the prompts below and select the default responses:
After installing this patch, MATLAB Installation is continued.

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6. Following MATLAB installation, the BAX Q7 application installation will be initiated. Read the prompts carefully. Choose the default responses. Welcome Window ­ click Next.
Calibration File Warning ­ ENSURE YOU HAVE BACKED UP THE CALIBRATION FILE. Check the box and click Next.

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License Agreement. Check Accept Terms box and click Next.
Custom Setup. Click Next.
Password Protection. BAX default is disabled password protection. Choose an option for your lab, then click Next.

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Ready to Install Program. Click Install.
Installing BAX System Q7 Software. During installation, an Error Log Reporting window will pop up. We recommend NOT checking the box so the system can collect software and/or hardware errors in the Log Files to assist Diagnostics Support in troubleshooting. However, please review and decide what is appropriate for your lab. Select Next to complete the installation.

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InstallShield Wizard Complete. Select Finish.
Click on the desktop icon to initiate the program. The new open screen will display software version 5.0.1.16813.
Enter the Instrument Name and Serial Number. · This will appear on reports and should be utilized.

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7. Check system’s calibration
From the menu bar, select Diagnostics > Calibration to open the Q7 Calibration Diagnostics window Click the Check Calibration button to determine the status: If calibration is available, no further actions are needed. If calibration is NOT optimal or NOT found:
Import the backed-up calibration file by selecting Operations > BAX Maintenance > Import Calibration from the menu bar and selecting the backed-up calibration file from step 2. To utilize many foodproof assays, additional calibration using the HEX calibration kit must be performed. Please follow the onboard instructions in the BAX Software to perform calibration.

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Appendix A: Algorithm Analysis across Software Versions

The table below provides information to identify algorithm consistency more easily across software versions and validations. The assay-specific algorithm has not changed since the analysis version listed.

Product Number
KIT2000 KIT2001 KIT2002 KIT2003 KIT2004 KIT2005 KIT2006 KIT2007 KIT2008 KIT2009 KIT2010 KIT2011 KIT2016 KIT2017 KIT2018 KIT2019 KIT2020 KIT2021 KIT2039 KIT230131 KIT230145

Assay
BAX System Real-Time PCR Assay for E. coli O157:H7 BAX System PCR Assay for Cronobacter (E. sakazakii) BAX System PCR Assay for L. monocytogenes 24E BAX System PCR Assay for Genus Listeria 24E BAX System PCR Assay for E. coli O157:H7 MP BAX System Real-Time PCR Assay for L. monocytogenes BAX System Real-Time PCR Assay for Salmonella BAX System Real-Time PCR Assay for Shigella BAX System Real-Time PCR Assay for STEC Panel 1 BAX System Real-Time PCR Assay for STEC Panel 2 BAX System Real-Time PCR Assay for Vibrio BAX System PCR Assay for Salmonella 2 BAX System PCR Assay for Genus Listeria BAX System PCR Assay for L. monocytogenes BAX System Real-Time PCR Assay for Campylobacter BAX System Real-Time PCR Assay for Genus Listeria BAX System Real-Time PCR Assay for Staphylococcus aureus BAX System Real-Time PCR Assay for STEC Screening BAX System Real-Time PCR Assay for E. coli O157:H7 Exact foodproof Salmonella plus Cronobacter Detection LyoKit foodproof Aspergillus Detection LyoKit (Real-time only)

BAX Q7 Software Version with Same Algorithm as v5.0
4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 4.0 5.0 5.0

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Documents / Resources

hygiena BAX System Q7 Software Upgrade [pdf] User Guide
24E, KIT230088, KIT230092, KIT230129, KIT230099, KIT230106, KIT230103, KIT230077, KIT230145, KIT230137, KIT230119, KIT230134, KIT230131, KIT230117, KIT230112, BAX System Q7 Software Upgrade, BAX, System Q7 Software Upgrade, Q7 Software Upgrade, Software Upgrade

References

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