User Guide for Howe Sound Research models including: TECHPBA 325, TECHPBA 325 Proteomic Biomarker Analytics, TECHPBA 325, Proteomic Biomarker Analytics, Biomarker Analytics, Analytics
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Proteomic Biomarker Analytics Markets | Howe Sound Research - Howe Sound Research
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DocumentDocumentQuick Brown Fox RESEARCH REPORT Proteomic Biomarker Analytics Markets 2nd Edition Forecasts by Application, Technology, Product and Place. With Executive and Consultant Guides. 2025 to 2029 Proteomic Biomarker Analytics Page | 2 Howe Sound Research is a market research and consulting company based in Vancouver, British Columbia, Canada. In our spare time we like to sail in a large body of water nearby called Howe Sound. We publish market research reports that address scientific industries with an emphasis on Biotechnology and Clinical Diagnostic markets. We consider ourselves experts in these areas. We approach market research differently than other companies. At any one time we have a limited number of reports, and we update them frequently, sometimes several times a year. Our reports are prepared by people who understand the industry and have worked and studied in the area. 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Proteomic Biomarker Analytics Page | 4 Table of Contents 1 Market Guides ..................................................................................................................15 1.1 Situation Analysis .............................................................................................................. 16 1.2 Guide for Executives and Marketing Staff ..................................................................... 18 1.3 Guide for Investment Analysts and Management Consultants ................................... 19 1.4 Impact of Artificial Intelligence....................................................................................... 20 2 Introduction and Market Definition ................................................................................21 2.1 What are Proteomic Biomarker Analytics? .................................................................... 22 2.2 Proteomics and Drug Development .............................................................................. 23 2.3 Market Definition .............................................................................................................. 24 2.3.1 Market Size .................................................................................................................... 24 2.3.2 Currency ....................................................................................................................... 24 2.3.3 Years .............................................................................................................................. 24 2.4 Methodology.................................................................................................................... 25 2.4.1 Methodology ................................................................................................................ 25 2.4.2 Sources .......................................................................................................................... 25 2.4.3 Authors .......................................................................................................................... 25 3 Proteomic Biomarker Analytics Guide to Technologies .............................................27 3.1 Methods ............................................................................................................................ 28 3.1.1 Separation techniques and electrophoresis.............................................................. 28 3.1.2 Mass spectrometry ....................................................................................................... 28 3.1.3 Chromatography ......................................................................................................... 29 3.1.4 Blotting .......................................................................................................................... 29 3.1.5 Protein complementation assays and interaction screens ...................................... 29 3.1.6 Protein structure prediction ......................................................................................... 29 Proteomic Biomarker Analytics Page | 5 3.1.7 Protein databases ........................................................................................................ 30 4 Industry Overview.............................................................................................................31 4.1 Players in a Dynamic Market........................................................................................... 32 4.2 Academic Research Lab ................................................................................................ 33 4.3 Diagnostic Test Developer............................................................................................... 33 4.4 Instrumentation Supplier .................................................................................................. 34 4.5 Chemical/Reagent Supplier ........................................................................................... 34 4.6 Pathology Supplier ........................................................................................................... 34 4.7 Independent Clinical Laboratory ................................................................................... 34 4.8 Public National/regional Laboratory .............................................................................. 35 4.9 Hospital Laboratory.......................................................................................................... 35 4.10 Physicians Office Lab (POLS)........................................................................................... 36 4.11 Audit Body ........................................................................................................................ 36 4.12 Certification Body ............................................................................................................ 37 5 Market Trends ...................................................................................................................38 5.1 Factors Driving Growth .................................................................................................... 39 5.1.1 Drug Development ...................................................................................................... 39 5.1.2 Companion Dx ............................................................................................................. 40 5.1.3 Fertile Research ............................................................................................................ 40 5.1.4 Technology Convergence .......................................................................................... 40 5.2 Factors Limiting Growth ................................................................................................... 41 5.2.1 The Cost Curve ............................................................................................................. 41 5.2.2 Capacity Constraints ................................................................................................... 41 5.2.3 Market Lag.................................................................................................................... 42 6 Proteomic Analytics Recent Developments ..................................................................43 6.1 Recent Developments Importance and How to Use This Section ............................ 44 6.1.1 Importance of These Developments .......................................................................... 44 Proteomic Biomarker Analytics Page | 6 6.1.2 How to Use This Section................................................................................................ 44 6.2 Sapient Partnering With Alamar Bio to Offer Proteomics.............................................. 44 6.3 Spear Bio Funded for Protein-Based Diagnostics........................................................... 45 6.4 Salignostics, Sheba Medical Partner on Saliva-Based Cancer Test ............................. 46 6.5 Key Proteo Applies for Newborn Screening Kit to FDA ................................................. 46 6.6 Mass Spec Test to Detect Ovarian Cancer ................................................................... 47 6.7 Proteomic Multiple Sclerosis Test Gaining Traction ........................................................ 50 6.8 Emory U Protein Panel Could Diagnose Alzheimer's Disease........................................ 54 6.9 Amprion's Parkinson's Disease Dx Shows Strong Performance ..................................... 56 6.10 Single-Cell Proteomics Bypasses Bottlenecks................................................................. 59 6.11 SomaLogic Seeks 'Strategic Alternatives' for Dx Business.............................................. 64 6.12 Alzheimer's Dx Study to Add Genomic, Proteomic Profiling ......................................... 65 6.13 NanoDx Prepares for POC Platform Commercialization .............................................. 68 6.14 DeepMind AI Predicts 3D Structure of Every Protein ..................................................... 71 6.15 Quanterix Slashing Workforce by 25 Percent................................................................. 74 6.16 Study Shows Potential of NanoMosaic's Platform for Biomarker Development.......... 75 6.17 Exact Sciences Bolsters Plasma Proteomics Tech With $15M Purchase of OmicEra .. 78 6.18 PrognomiQ Exploring Multiomic Markers for Variety of Cancer Dx Applications ....... 82 6.19 Octave Bioscience Building Evidence Base for Multiple Sclerosis Test ........................ 84 6.20 Proteomics Goes Public................................................................................................... 86 7 Profiles of Key Proteomic Biomarker Analytic Companies............................................91 7.1 Abbott Laboratories......................................................................................................... 92 7.2 Abcam .............................................................................................................................. 93 7.3 Agilent ............................................................................................................................... 94 7.4 Amprion ............................................................................................................................ 95 7.5 ATUM ................................................................................................................................. 96 7.6 BasePair Biotechnologies ................................................................................................ 97 Proteomic Biomarker Analytics Page | 7 7.7 Beckman Coulter Diagnostics (Danaher) ...................................................................... 98 7.8 Becton, Dickinson and Company .................................................................................. 99 7.9 Biomatik........................................................................................................................... 100 7.10 Bio-Rad Laboratories, Inc............................................................................................... 101 7.11 Bio-Techne ...................................................................................................................... 102 7.12 Bruker............................................................................................................................... 103 7.13 C2N Diagnostics ............................................................................................................. 104 7.14 Cepheid (Danaher) ....................................................................................................... 105 7.15 Diadem Diagnostics....................................................................................................... 106 7.16 Eve Technologies ........................................................................................................... 107 7.17 Fujirebio ........................................................................................................................... 108 7.18 Hybrigenics Services....................................................................................................... 109 7.19 MRM Proteomics Inc. ..................................................................................................... 110 7.20 NanoDx ........................................................................................................................... 111 7.21 Nautilus Biotechnology .................................................................................................. 112 7.22 Nicoya............................................................................................................................. 113 7.23 Nuclera ........................................................................................................................... 114 7.24 Olink................................................................................................................................. 116 7.25 Qiagen ............................................................................................................................ 117 7.26 Quanterix ........................................................................................................................ 118 7.27 Roche Diagnostics ......................................................................................................... 119 7.28 Second Genome ........................................................................................................... 120 7.29 Siemens Healthineers ..................................................................................................... 121 7.30 Sphingotec ..................................................................................................................... 122 7.31 Thermo Fisher Scientific .................................................................................................. 123 7.32 Unchained Labs ............................................................................................................. 124 8 Global Proteomic Analytics Markets ............................................................................125 Proteomic Biomarker Analytics Page | 8 8.1 PROTEIN ANALYTICS Global Market Overview by Country ...................................... 126 8.1.1 Table Global Market by Country............................................................................ 126 8.1.2 Chart - Global Market by Country ............................................................................ 127 8.2 Global Market by Application - Overview ................................................................... 128 8.2.1 Table Global Market by Application ..................................................................... 128 8.2.2 Chart Global Market by Application Segments Growth ................................... 129 8.2.3 Chart Global Market by Application Base/Final Comparison .......................... 130 8.2.4 Chart Global Market by Application Base Year ................................................ 131 8.2.5 Chart Global Market by Application Final Year................................................. 132 8.2.6 Chart Global Market by Application Share by Year.......................................... 133 8.3 Global Market by Technology - Overview................................................................... 134 8.3.1 Table Global Market by Technology ..................................................................... 134 8.3.2 Chart Global Market by Technology Segments Growth................................... 135 8.3.3 Chart Global Market by Technology Base/Final Comparison .......................... 136 8.3.4 Chart Global Market by Technology Base Year ................................................ 137 8.3.5 Chart Global Market by Technology Final Year................................................. 138 8.3.6 Chart Global Market by Technology Share by Year.......................................... 139 8.4 Global Market by Product - Overview ......................................................................... 140 8.4.1 Table Global Market by Product............................................................................ 140 8.4.2 Chart Global Market by Product Segments Growth ......................................... 141 8.4.3 Chart Global Market by Product Base/Final Comparison................................. 142 8.4.4 Chart Global Market by Product Base Year....................................................... 143 8.4.5 Chart Global Market by Product Final Year ....................................................... 144 8.4.6 Chart Global Market by Product Share by Year ................................................ 145 8.5 Global Market by Place - Overview ............................................................................. 146 8.5.1 Table Global Market by Place................................................................................ 146 8.5.2 Chart Global Market by Place Segments Growth ............................................. 147 Proteomic Biomarker Analytics Page | 9 8.5.3 Chart Global Market by Place Base/Final Comparison .................................... 148 8.5.4 Chart Global Market by Place Base Year........................................................... 149 8.5.5 Chart Global Market by Place Final Year ........................................................... 150 8.5.6 Chart Global Market by Place Share by Year.................................................... 151 9 Global PROTEIN ANALYTICS Markets By Application ................................................152 9.1 PROTEIN ANALYTICS Drug Discovery............................................................................. 153 9.1.1 Table PROTEIN ANALYTICS Drug Discovery by Country ........................................ 153 9.1.2 Chart - PROTEIN ANALYTICS Drug Discovery Growth .............................................. 154 9.2 PROTEIN ANALYTICS Research Application.................................................................. 155 9.2.1 Table PROTEIN ANALYTICS Research Application by Country ............................. 155 9.2.2 Chart - PROTEIN ANALYTICS Research Application Growth ................................... 156 9.3 PROTEIN ANALYTICS Clinical Dx..................................................................................... 157 9.3.1 Table PROTEIN ANALYTICS Clinical Dx by Country ................................................ 157 9.3.2 Chart - PROTEIN ANALYTICS Clinical Dx Growth ...................................................... 158 9.4 PROTEIN ANALYTICS Other Applications ...................................................................... 159 9.4.1 Table PROTEIN ANALYTICS Other Applications by Country.................................. 159 9.4.2 Chart - PROTEIN ANALYTICS Other Applications Growth ........................................ 160 10 Global PROTEIN ANALYTICS Markets By Technology...........................................161 10.1 PROTEIN ANALYTICS Mass Spectrometry ...................................................................... 162 10.1.1 Table PROTEIN ANALYTICS Mass Spectrometry by Country.............................. 162 10.1.2 Chart - PROTEIN ANALYTICS Mass Spectrometry Growth .................................... 163 10.2 PROTEIN ANALYTICS ELISA/Beads.................................................................................. 164 10.2.1 Table PROTEIN ANALYTICS ELISA/Beads by Country ......................................... 164 10.2.2 Chart - PROTEIN ANALYTICS ELISA/Beads Growth................................................ 165 10.3 PROTEIN ANALYTICS Hybrid Multiplex............................................................................ 166 10.3.1 Table PROTEIN ANALYTICS Hybrid Multiplex by Country ................................... 166 10.3.2 Chart - PROTEIN ANALYTICS Hybrid Multiplex Growth ......................................... 167 Proteomic Biomarker Analytics Page | 10 10.4 PROTEIN ANALYTICS Other Technology........................................................................ 168 10.4.1 Table PROTEIN ANALYTICS Other Technology by Country ............................... 168 10.4.2 Chart - PROTEIN ANALYTICS Other Technology Growth...................................... 169 11 Global PROTEIN ANALYTICS Markets By Product .................................................170 11.1 PROTEIN ANALYTICS Instruments ................................................................................... 171 11.1.1 Table PROTEIN ANALYTICS Instruments by Country ........................................... 171 11.1.2 Chart - PROTEIN ANALYTICS Instruments Growth ................................................. 172 11.2 PROTEIN ANALYTICS Kits & Reagents ............................................................................ 173 11.2.1 Table PROTEIN ANALYTICS Kits & Reagents by Country.................................... 173 11.2.2 Chart - PROTEIN ANALYTICS Kits & Reagents Growth .......................................... 174 11.3 PROTEIN ANALYTICS Services......................................................................................... 175 11.3.1 Table PROTEIN ANALYTICS Services by Country ................................................ 175 11.3.2 Chart - PROTEIN ANALYTICS Services Growth....................................................... 176 12 Global PROTEIN ANALYTICS Markets By Place .....................................................177 12.1 PROTEIN ANALYTICS Academic .................................................................................... 178 12.1.1 Table PROTEIN ANALYTICS Academic by Country............................................ 178 12.1.2 Chart - PROTEIN ANALYTICS Academic Growth .................................................. 179 12.2 PROTEIN ANALYTICS Pharma/Biotech........................................................................... 180 12.2.1 Table PROTEIN ANALYTICS Pharma/Biotech by Country .................................. 180 12.2.2 Chart - PROTEIN ANALYTICS Pharma/Biotech Growth ........................................ 181 12.3 PROTEIN ANALYTICS Clinical .......................................................................................... 182 12.3.1 Table PROTEIN ANALYTICS Clinical by Country ................................................. 182 12.3.2 Chart - PROTEIN ANALYTICS Clinical Growth........................................................ 183 12.4 PROTEIN ANALYTICS Other Place .................................................................................. 184 12.4.1 Table PROTEIN ANALYTICS Other Place by Country ......................................... 184 12.4.2 Chart - PROTEIN ANALYTICS Other Place Growth................................................ 185 13 Appendices ...............................................................................................................186 Proteomic Biomarker Analytics Page | 11 13.1 Clinical Laboratory Fee Schedule................................................................................. 187 13.2 The Most Used IVD Assays.............................................................................................. 295 13.3 The Highest Grossing Assays .......................................................................................... 300 13.4 The Changing IVD Menu ............................................................................................... 305 13.4.1 Approved IVD Test Menu History ........................................................................... 305 13.5 The Changing Picture on Reimbursement ................................................................... 306 Proteomic Biomarker Analytics Page | 12 Table of Tables Table 1 Market Players by Type ..................................................................................................... 33 Table 2 Five Factors Driving Growth ............................................................................................... 39 Table 3 Three Factors Limiting Growth ........................................................................................... 41 Table 4 Market Size by Country .................................................................................................... 126 Table 5 Global Market by Application ........................................................................................ 128 Table 6 Global Market by Technology ........................................................................................ 134 Table 7 Global Market by Product............................................................................................... 140 Table 8 Global Market by Place................................................................................................... 146 Table 9 PROTEIN ANALYTICS Drug Discovery by Country .......................................................... 153 Table 10 PROTEIN ANALYTICS Research Application by Country .............................................. 155 Table 11 PROTEIN ANALYTICS Clinical Dx by Country ................................................................. 157 Table 12 PROTEIN ANALYTICS Other Applications by Country................................................... 159 Table 13 PROTEIN ANALYTICS Mass Spectrometry by Country ................................................. 162 Table 14 PROTEIN ANALYTICS Hybrid Multiplex by Country ........................................................ 166 Table 15 PROTEIN ANALYTICS Other Technology by Country .................................................... 168 Table 16 PROTEIN ANALYTICS Instruments by Country............................................................... 171 Table 17 PROTEIN ANALYTICS Kits & Reagents by Country......................................................... 173 Table 18 PROTEIN ANALYTICS Services by Country ..................................................................... 175 Table 19 PROTEIN ANALYTICS Academic by Country................................................................ 178 Table 20 PROTEIN ANALYTICS Pharma/Biotech by Country ....................................................... 180 Table 21 PROTEIN ANALYTICS Clinical by Country ...................................................................... 182 Table 22 PROTEIN ANALYTICS Other Place by Country .............................................................. 184 Table 23 Clinical Lab Fee Schedule ............................................................................................. 187 Table 24 The Most Common Assays ............................................................................................ 295 Proteomic Biomarker Analytics Page | 13 Table 25 Largest Revenue Assays................................................................................................. 300 Table of Figures Figure 1 The Road to Diagnostics ................................................................................................... 32 Figure 2 Base year Global Market Share Chart........................................................................... 127 Figure 3 PROTEIN ANALYTICS Market by Application Segments Growth ............................... 129 Figure 4 PROTEIN ANALYTICS Market by Application Base vs. final ........................................ 130 Figure 5 PROTEIN ANALYTICS Market Base year .......................................................................... 131 Figure 6 PROTEIN ANALYTICS Market Final Year .......................................................................... 132 Figure 7 PROTEIN ANALYTICS Application Share by Year ........................................................... 133 Figure 8 PROTEIN ANALYTICS Market by Technology Segments Growth ............................... 135 Figure 9 PROTEIN ANALYTICS Market by Technology Base vs. final ........................................ 136 Figure 10 PROTEIN ANALYTICS Market by Technology Base year .............................................. 137 Figure 11 PROTEIN ANALYTICS Market by Technology Final Year .............................................. 138 Figure 12 PROTEIN ANALYTICS Technology Share by Year ......................................................... 139 Figure 13 PROTEIN ANALYTICS Market by Product Segments Growth .................................... 141 Figure 14 PROTEIN ANALYTICS Market by Product Base vs. final ............................................. 142 Figure 15 PROTEIN ANALYTICS Market by Product Base year .................................................... 143 Figure 16 PROTEIN ANALYTICS Market by Product Final Year..................................................... 144 Figure 17 Product Share by Year .................................................................................................. 145 Figure 18 PROTEIN ANALYTICS Market by Place Segments Growth........................................ 147 Figure 19 PROTEIN ANALYTICS Market by Place Base vs. final................................................. 148 Figure 20 PROTEIN ANALYTICS Market by Place Base year ........................................................ 149 Figure 21 PROTEIN ANALYTICS Market by Place Final Year ........................................................ 150 Figure 22 Place Share by Year...................................................................................................... 151 Proteomic Biomarker Analytics Page | 14 Figure 23 PROTEIN ANALYTICS Drug Discovery Growth .............................................................. 154 Figure 24 PROTEIN ANALYTICS Research Application Growth ................................................... 156 Figure 25 PROTEIN ANALYTICS Clinical Dx Growth ...................................................................... 158 Figure 26 PROTEIN ANALYTICS Other Applications Growth ........................................................ 160 Figure 27 PROTEIN ANALYTICS Mass Spectrometry Growth........................................................ 163 Figure 28 PROTEIN ANALYTICS ELISA/Beads Growth ................................................................... 165 Figure 29 PROTEIN ANALYTICS Hybrid Multiplex Growth ............................................................. 167 Figure 30 PROTEIN ANALYTICS Other Technology Growth ......................................................... 169 Figure 31 PROTEIN ANALYTICS Instruments Growth ..................................................................... 172 Figure 32 PROTEIN ANALYTICS Kits & Reagents Growth.............................................................. 174 Figure 33 PROTEIN ANALYTICS Services Growth .......................................................................... 176 Figure 34 PROTEIN ANALYTICS Academic Growth...................................................................... 179 Figure 35 PROTEIN ANALYTICS Pharma/Biotech Growth ............................................................ 181 Figure 36 PROTEIN ANALYTICS Clinical Growth ........................................................................... 183 Figure 37 PROTEIN ANALYTICS Other Place Growth.................................................................... 185 Figure 38 The Growing Menu of Approved Assays ..................................................................... 305 Figure 39 The Changing Reimbursement Picture........................................................................ 306Microsoft: Print To PDF