1. Introduction
The Waveshare RP2350-Plus Development Board is a high-performance, Pico-like microcontroller unit (MCU) board designed around the Raspberry Pi RP2350A chip. This advanced chip features a unique dual-core and dual-architecture design, incorporating both an Arm Cortex-M33 processor and a Hazard 3 RISC-V processor, capable of flexible clock speeds up to 150 MHz.
Equipped with 520KB of Static RAM and 16MB of on-board Flash memory, the RP2350-Plus offers ample resources for a wide range of embedded projects. Its compact design, Type-C USB connector, and lithium battery recharge/discharge header make it versatile for both desktop development and mobile applications.
This manual provides essential information for setting up, operating, and maintaining your RP2350-Plus Development Board, along with detailed specifications and troubleshooting tips.
2. Package Contents
Upon opening the package, please verify that all components are present and in good condition. The standard package for the RP2350-Plus-16MB-M includes:
- 1x RP2350-Plus-16MB Development Board with pre-soldered header

Figure 2.1: RP2350-Plus-16MB with pre-soldered header as included in the package.
3. Product Overview
3.1 Key Features
- Microcontroller: Raspberry Pi RP2350A dual-core (Arm Cortex-M33 and Hazard 3 RISC-V) up to 150 MHz.
- Memory: 520KB SRAM, 16MB on-board Flash memory.
- Connectivity: USB 1.1 with device and host support via Type-C connector.
- Power Management: Lithium battery recharge/discharge header, onboard DC-DC chip MP28164 (max 2A load).
- GPIO: 26 multi-function GPIO pins.
- Peripherals: 2x SPI, 2x I2C, 2x UART, 4x 12-bit ADC, 16x controllable PWM channels.
- Programming: Drag-and-drop programming via USB mass storage.
- Additional Features: Low-power sleep and dormant modes, accurate clock and timer, temperature sensor, accelerated floating-point libraries, 12x Programmable I/O (PIO) state machines.

Figure 3.1: RP2350-Plus MCU Board overview.
3.2 Board Layout and Components
Familiarize yourself with the various components and pinouts of the RP2350-Plus board. This section details the key elements for proper usage and connection.

Figure 3.2: Detailed board layout with numbered components, GPIO pinout, and dimensions.
Key Components Reference:
- LED: User LED (not power indicator).
- USB Type-C connector: For power, data, and programming.
- ETA6096: High efficiency Lithium battery recharge manager.
- MP28164: High efficiency DC-DC buck-boost chip.
- BOOT button: Press when resetting to enter download mode.
- On-board Flash memory: 16MB (W25Q128JVSIQ).
- RESET button: Resets the microcontroller.
- RP2350A: Dual-core and dual-architecture design, up to 150 MHz operating frequency.
- Battery header: MX1.25 header for 3.7V Lithium battery, allows recharging the battery and powering the board at the same time.
- Pinout: Compatible with Raspberry Pi Pico 2.
- USB test points: Connecting to USB interface.
- BOOT test point: Connecting to BOOT button.
- DEBUG points: For debugging purposes.
3.3 GPIO Pinout
The RP2350-Plus features 26 multi-function GPIO pins, offering flexible development and integration. Refer to the pinout diagram for detailed assignments and capabilities.

Figure 3.3: GPIO Pinout Diagram.
3.4 Outline Dimensions
The physical dimensions of the RP2350-Plus board are provided below for integration into your projects.

Figure 3.4: Outline Dimensions (Unit: mm).
4. Setup Guide
4.1 Initial Connection
- Connect the RP2350-Plus board to your computer using a standard USB Type-C cable.
- The board should be recognized as a mass storage device (like a USB drive) when in bootloader mode. To enter bootloader mode, hold down the BOOT button while plugging in the USB cable, then release the BOOT button.
- If the board is not recognized, ensure your USB cable supports data transfer and is not just a charging cable.
4.2 Software Setup
The RP2350-Plus supports development using C/C++ SDK and MicroPython, offering flexibility for various programming needs.

Figure 4.1: C/C++, MicroPython support.
4.2.1 C/C++ Development
For C/C++ development, you can use the official Raspberry Pi Pico C/C++ SDK. This SDK can be utilized from the command line or integrated development environments (IDEs) such as Visual Studio Code and Eclipse. Refer to the official Raspberry Pi Pico documentation for detailed setup instructions for the C/C++ SDK.
4.2.2 MicroPython Development
MicroPython is a lean and efficient implementation of the Python 3 programming language that runs directly on embedded hardware like the RP2350-Plus. To get started with MicroPython:
- Download the appropriate MicroPython UF2 firmware file for the RP2350-Plus from the Waveshare wiki or official MicroPython website.
- Enter bootloader mode (hold BOOT and plug in USB).
- Drag and drop the downloaded UF2 file onto the RPI-RP2 mass storage device that appears. The board will automatically reboot into MicroPython.
- Use an IDE like Thonny to connect to the board and begin programming.
5. Operating Instructions
5.1 Programming the Board
The RP2350-Plus supports drag-and-drop programming, making it easy to upload new firmware or MicroPython scripts:
- Ensure the board is in bootloader mode (hold BOOT button while connecting USB, then release). A removable drive named "RPI-RP2" will appear on your computer.
- Locate your compiled firmware (.uf2 file for MicroPython or C/C++).
- Drag and drop the .uf2 file onto the "RPI-RP2" drive.
- The board will automatically disconnect, flash the new firmware, and then reboot.
5.2 Using GPIO and Peripherals
The 26 multi-function GPIO pins can be configured for various purposes, including digital input/output, analog input (ADC), and specialized functions like SPI, I2C, UART, and PWM. Refer to the pinout diagram (Figure 3.3) and the specific SDK documentation for detailed programming examples and pin assignments.
- Digital I/O: Control LEDs, read button states, etc.
- Analog-to-Digital Converter (ADC): Read analog sensor values. The board has 4x 12-bit ADC channels.
- SPI, I2C, UART: Communicate with external sensors, displays, and other modules.
- PWM: Control motor speeds, LED brightness, and generate audio signals. The board offers 16 controllable PWM channels.
- PIO State Machines: Utilize the 12 Programmable I/O (PIO) state machines for custom peripheral support and high-speed bit-banging.
5.3 Battery Operation
The RP2350-Plus includes a lithium battery recharge/discharge header (MX1.25) and an onboard ETA6096 chip, allowing it to be powered by and charge a 3.7V lithium battery. This feature is ideal for portable applications.
- Connect a compatible 3.7V lithium battery to the MX1.25 header.
- The board can be powered directly from the battery.
- When the board is connected via USB-C, the battery will automatically charge.
- Ensure correct polarity when connecting the battery to avoid damage.
6. Maintenance
To ensure the longevity and optimal performance of your Waveshare RP2350-Plus Development Board, follow these maintenance guidelines:
- Handling: Always handle the board by its edges to avoid touching components, especially the pins, which can be sensitive to static electricity.
- Storage: Store the board in an anti-static bag when not in use, and keep it in a dry, cool environment away from direct sunlight and extreme temperatures.
- Cleaning: If necessary, gently clean the board with a soft, dry brush or compressed air to remove dust. Avoid using liquids or abrasive cleaners.
- Power Supply: Use only appropriate power sources (USB-C or compatible 3.7V lithium battery). Do not exceed specified voltage limits.
- Firmware Updates: Regularly check the Waveshare official website or wiki for the latest firmware updates to benefit from bug fixes and new features.
7. Troubleshooting
This section addresses common issues you might encounter with your RP2350-Plus Development Board.
| Problem | Possible Cause | Solution |
|---|---|---|
| Board not recognized by computer (no "RPI-RP2" drive). |
|
|
| Firmware upload fails or board doesn't reboot after drag-and-drop. |
|
|
| MicroPython/C++ code not running as expected. |
|
|
| Board gets hot during operation. |
|
|
8. Specifications
Detailed technical specifications for the Waveshare RP2350-Plus Development Board:
| Feature | Detail |
|---|---|
| Microcontroller | Raspberry Pi RP2350A (Dual-core Arm Cortex-M33 + Dual-core Hazard 3 RISC-V) |
| Clock Speed | Up to 150 MHz |
| SRAM | 520KB |
| On-board Flash Memory | 16MB (W25Q128JVSIQ) |
| USB Interface | USB 1.1 Host/Device, Type-C connector |
| GPIO Pins | 26 multi-function GPIO pins |
| SPI | 2x |
| I2C | 2x |
| UART | 2x |
| ADC | 4x 12-bit ADC |
| PWM Channels | 16 controllable PWM channels |
| PIO State Machines | 12x |
| Power Management | Onboard DC-DC chip MP28164 (max 2A load), Lithium battery recharge/discharge header (MX1.25) |
| Operating Modes | Low-power sleep and dormant modes |
| Dimensions | 51.00 mm x 17.78 mm (approx. 2.01 x 0.70 inches) |
| Weight | 0.317 ounces (approx. 9 grams) |
| Manufacturer | Waveshare |
| Country of Origin | China |
9. Support and Warranty
9.1 Technical Support
For technical assistance, detailed documentation, tutorials, and community forums, please visit the official Waveshare website or their product wiki. These resources provide comprehensive guides and solutions for common development challenges.
Waveshare Official Website: www.waveshare.com
Look for the specific product page for the RP2350-Plus Development Board for the most up-to-date information and downloads.
9.2 Warranty Information
Waveshare products typically come with a standard manufacturer's warranty covering defects in materials and workmanship. The specific terms and duration of the warranty may vary by region and product. Please retain your proof of purchase for warranty claims.
For detailed warranty terms and conditions, refer to the warranty policy section on the Waveshare official website or contact their customer service directly.





