Introduction
Thank you for choosing the Perixx PERIMICE-621R Wireless Mouse. This manual provides detailed instructions for setting up, operating, and maintaining your new wireless mouse. Designed for comfort and efficiency, the PERIMICE-621R offers silent clicks, adjustable DPI, and a reliable 2.4 GHz wireless connection, making it ideal for both desktop and laptop use.
Key Features:
- Silent Click Buttons: Enjoy a quiet working environment without distracting click noises.
- Ergonomic Design: Sculpted shape provides palm support for comfortable long-term use.
- Wireless 2.4 GHz Connection: Reliable plug-and-play connectivity with up to 33ft operating range.
- Adjustable DPI: Switch between 1000 and 1600 DPI for precise control.
- Wide Compatibility: Supports Windows 7/8/10/11, Mac OS X, Linux Ubuntu 16.04, Chromebook, Android, and Amazon Fire Tablet.
Setup Guide
Package Contents
Please ensure all items are present in the package:
- Perixx PERIMICE-621R Wireless Mouse
- USB Receiver
- Instruction Manual

Image: Package contents of the Perixx PERIMICE-621R Wireless Mouse, showing the mouse, USB receiver, and manual.
Battery Installation
The Perixx PERIMICE-621R requires one (1) AA battery (not included) for operation.
- Locate the battery compartment on the underside of the mouse.
- Gently slide the battery cover open.
- Insert one AA battery, ensuring the positive (+) and negative (-) terminals align correctly with the indicators inside the compartment.
- Close the battery cover until it clicks securely into place.

Image: The bottom of the mouse with the battery compartment open, indicating where to insert the AA battery and the location of the USB receiver.
Connecting the USB Receiver
The mouse connects wirelessly via a 2.4 GHz USB receiver.
- Remove the USB receiver from its storage slot on the underside of the mouse (next to the battery compartment).
- Plug the USB receiver into an available USB port on your computer (desktop or laptop).
- Your computer should automatically detect and install the necessary drivers. This is a plug-and-play device, requiring no additional software installation.

Image: The wireless mouse in use, demonstrating its plug-and-play capability with a computer setup.
Powering On/Off
To conserve battery life, the mouse features an ON/OFF switch.
- Locate the ON/OFF switch on the underside of the mouse.
- Slide the switch to the "ON" position to activate the mouse.
- Slide the switch to the "OFF" position when the mouse is not in use for extended periods, such as overnight or during travel.
Operating Instructions
Basic Functions
The PERIMICE-621R operates like a standard computer mouse:
- Left Click: Primary button for selecting items, opening files, etc.
- Right Click: Secondary button for context menus and additional options.
- Scroll Wheel: Used for scrolling through documents and web pages. It also functions as a middle click button.
Adjusting DPI (Sensitivity)
The mouse offers two DPI settings: 1000 DPI and 1600 DPI. DPI (Dots Per Inch) determines the sensitivity of the mouse cursor movement.
- To switch between 1000 DPI and 1600 DPI, simultaneously press and hold the Left Click button and the Scroll Wheel for approximately 3 seconds.
- The mouse will cycle between the two settings. Choose the sensitivity that best suits your task.

Image: Illustration showing the method to adjust the mouse's DPI settings by pressing the left click and scroll wheel simultaneously.
Silent Click Feature
The PERIMICE-621R is equipped with silent click buttons, significantly reducing the audible click sound. This feature is integrated into the design and requires no special activation.

Image: The mouse with a visual representation of its silent click feature, emphasizing a quiet operation.
Ergonomic Design
The mouse features a sculpted shape designed to provide optimal palm support and a comfortable grip, reducing strain during prolonged use.

Image: A user's hand on the mouse, highlighting the comfortable and ergonomic sculpted shape.
Maintenance
Cleaning Your Mouse
To ensure optimal performance and hygiene, regularly clean your mouse:
- Disconnect the USB receiver from your computer.
- Turn off the mouse using the ON/OFF switch.
- Use a soft, lint-free cloth lightly dampened with water or a mild cleaning solution to wipe the surface of the mouse.
- For optical sensor, use a dry cotton swab to gently clean any dust or debris.
- Avoid using harsh chemicals, abrasive cleaners, or excessive moisture.
Battery Replacement
When the mouse performance degrades or it stops responding, it's likely time to replace the AA battery. Follow the battery installation steps outlined in the Setup Guide.
Troubleshooting
If you encounter issues with your Perixx PERIMICE-621R Wireless Mouse, please refer to the following common problems and solutions:
| Problem | Possible Cause | Solution |
|---|---|---|
| Mouse not responding | Low battery; Mouse is off; USB receiver not connected; Driver issue. | Replace AA battery; Turn mouse ON; Ensure USB receiver is firmly plugged into a working USB port; Try a different USB port; Restart computer. |
| Erratic cursor movement | Dirty optical sensor; Uneven surface; Interference. | Clean the optical sensor on the bottom of the mouse; Use the mouse on a flat, non-reflective surface or a mouse pad; Move mouse closer to the USB receiver; Remove other wireless devices causing interference. |
| DPI not changing | Incorrect button combination or duration. | Ensure you are pressing and holding both the Left Click button and the Scroll Wheel simultaneously for 3 seconds. |
| Wireless connection issues | Distance from receiver; Obstructions; Interference. | Reduce distance between mouse and receiver (max 33ft); Remove large metal objects between mouse and receiver; Avoid using near other 2.4 GHz devices. |
Specifications
| Feature | Detail |
|---|---|
| Model Number | 12050 (PERIMICE-621R) |
| Connectivity Technology | Wireless 2.4 GHz |
| Movement Detection Technology | Optical |
| DPI Settings | 1000, 1600 |
| Product Dimensions | 4.41 x 2.8 x 1.54 inches (112 x 71 x 39mm) |
| Item Weight | 2.5 ounces (70.87 grams) |
| Battery Type | 1 x AA battery (not included) |
| Operating Range | Up to 33 feet (10 meters) |
| Compatibility | Windows 7/8/10/11, Mac OS X, Linux Ubuntu 16.04, Chromebook, Android, Amazon Fire Tablet |
| Special Features | Ergonomic Design, Lightweight, Portable, Silent Click |
Warranty Information
Perixx products are designed and manufactured to the highest quality standards. For specific warranty terms and conditions applicable to your region, please refer to the warranty card included with your product or visit the official Perixx website. Please retain your proof of purchase for warranty claims.
Customer Support
If you require further assistance or have questions not covered in this manual, please contact Perixx customer support. You can find contact information on the official Perixx website or through the retailer where you purchased the product.
Perixx Official Website: www.perixx.com





