1. Introduction
The Nuwave OxyPure ZERO E500 Air Purifier is designed to significantly improve indoor air quality by capturing a wide range of airborne pollutants. This manual provides essential information for the safe and effective operation and maintenance of your air purifier.

Figure 1.1: Nuwave OxyPure ZERO E500 Air Purifier with its mobile app interface.
Key Features:
- High Performance: Effectively purifies up to 966 sq. ft. in 1 hour.
- Advanced Filtration: Dual 3-stage filtration system with Bio-Guard® Technology, including stainless-steel pre-filters, Bio-Guard filters, and a Bio-Guard 360 filter.
- Superior Particle Capture: Captures 100% of airborne particle pollutants as small as 0.1 microns, including smoke, dust, pollen, pet hair, and harmful chemicals.
- Washable & Reusable Filters: Bio-Guard filters are washable and reusable, eliminating the need for frequent filter replacements.
- Smart Control: Wi-Fi enabled with app control, auto mode, and various fan speeds.
- Quiet Operation: Sleep mode operates at noise levels as low as 21.4 dB.
- Certified: Intertek Lab Certified, CARB Certified, CE Certified, ETL Certified, and Energy Star Certified.
2. Safety Information
Please read all safety instructions carefully before using the Nuwave OxyPure ZERO E500 Air Purifier. Failure to follow these instructions may result in electric shock, fire, or serious injury.
- Always unplug the air purifier before cleaning or performing any maintenance.
- Do not operate the air purifier with a damaged cord or plug.
- Keep the air purifier away from water or other liquids. Do not immerse the unit in water.
- Do not block air inlets or outlets. Ensure adequate space around the unit for proper airflow.
- This appliance is not intended for use by persons (including children) with reduced physical, sensory, or mental capabilities, or lack of experience and knowledge, unless they have been given supervision or instruction concerning use of the appliance by a person responsible for their safety.
- Do not use the air purifier in areas with high humidity, such as bathrooms.
- Do not use the air purifier near heat sources or open flames.
- Use only Nuwave authorized replacement parts and accessories.
3. Package Contents
Carefully unpack your Nuwave OxyPure ZERO E500 Air Purifier and ensure all items are present and undamaged. If any items are missing or damaged, please contact Nuwave customer support.
- 1 x Nuwave ZERO Smart Air Purifier Unit
- 2 x Stainless-steel Pre-filters (Pre-installed)
- 2 x Bio-Guard Filters (Pre-installed)
- 1 x Cylindrical Bio-Guard 360 Filter (Pre-installed)
- 1 x User Manual
4. Setup and Installation
Unpacking and Filter Installation:
- Remove the air purifier from its packaging.
- Open the filter compartments on the sides of the unit.
- Ensure all pre-installed filters (2 Stainless-steel Pre-filters, 2 Bio-Guard Filters, and 1 Cylindrical Bio-Guard 360 Filter) are securely in place and any protective packaging has been removed from them.
- Close the filter compartments securely.
Placement:
For optimal performance, place the air purifier on a flat, stable surface in the room where air purification is desired. Ensure there is at least 6 inches of clear space around all sides of the unit for proper air circulation.

Figure 4.1: Air purifier placement in a living room.

Figure 4.2: Air purifier placement in a bedroom.
The OxyPure ZERO is lightweight and includes ergonomic handles, making it easy to move between rooms or even between floors.

Figure 4.3: Easy transportation of the air purifier.
Power Connection:
Plug the power cord into a standard electrical outlet. The unit is now ready for operation.
5. Operation
The OxyPure ZERO E500 features intuitive touch screen controls and can also be controlled via a Wi-Fi enabled app.

Figure 5.1: Touch Screen Controls.
Control Panel Functions:
- Power Button: Turns the unit On/Off.
- Auto Mode: The air purifier utilizes particle and odor sensors to continuously monitor air quality and automatically adjusts the fan speed for optimal purification.
- Ultimate Clean Mode: Monitors air quality and automatically adjusts the fan to a higher speed when advanced sensors detect a drop in air quality, cleaning the air quickly and efficiently.
- Fan Speed: Manually select between 6 fan speeds (Low, Medium, High, etc.).
- Sleep Mode: Automatically turns off all indicator lights and allows for quieter fan speed and noise level to promote ideal sleeping conditions.
- Timer: Customize run time with options for ½, 1, 2, 4, 8, or 12 hours.
- Turbo Mode: Operates at maximum speed for a set amount of time (½, 1, or 2 hours) for rapid cleaning.

Figure 5.2: Auto Mode operation.

Figure 5.3: Ultimate Clean Mode operation.

Figure 5.4: Fan Speed and Sleep Mode.

Figure 5.5: Timer and Turbo Mode.
Air Quality Indicators:
The OxyPure ZERO E500 features two sensors to detect both air particles and odors. Bright air quality indicators show precisely how clean or dirty your air is. These sensors and indicators can automatically adjust fan speed when Auto Mode is enabled.

Figure 5.6: Two Sensors & Air Quality Indicators.
Wi-Fi Connectivity:
The OxyPure ZERO E500 is Wi-Fi capable. Once connected to your home Wi-Fi network, you can remotely monitor and control the air quality in your home anytime, anywhere using the NuWave Connect app on your smartphone.

Figure 5.7: Wi-Fi Enabled Smart Device and App Control.
6. Maintenance
Regular maintenance ensures the longevity and optimal performance of your Nuwave OxyPure ZERO E500 Air Purifier. The filters are designed for long-lasting, reusable use.

Figure 6.1: Dual 3-Stage Filtration System.
Filter Care:
The OxyPure ZERO E500 features a DUAL 3-STAGE FILTRATION system with washable and reusable filters, meaning ZERO waste and ZERO filter replacements are needed. Unlike traditional air purifiers that require purchasing expensive replacement filters 1-2 times per year, the OxyPure Zero E500 never requires replacement filters.
- Stainless-steel Pre-filters: These filters capture larger particles, pollutants, and irritants such as pollen, dust, and pet hair. They are made from rust-free 18/8 stainless-steel and capture particles above 50 microns.
- Bio-Guard Filters: These Hi-Tech Bio-Guard Filters trap particles and harmful pollutants as small as 0.01 microns.
- Bio-Guard 360 Filter: The largest of the OxyPure Zero E500 filters, the Bio-Guard 360 uses patent-pending technology to trap particles as small as 0.1 microns, which is 66% smaller than what most HEPA filters can capture.

Figure 6.2: Various filter types including Stainless-steel Pre-filters.

Figure 6.3: Two Stainless Steel Pre-Filters.

Figure 6.4: Two Bio-Guard Filters.

Figure 6.5: Bio-Guard 360 Filter.
Cleaning Instructions:
The washable and reusable filters should be cleaned periodically based on usage and air quality. Refer to the full user manual (link below) for detailed cleaning instructions for each filter type.
For external cleaning, wipe the exterior of the air purifier with a soft, damp cloth. Do not use abrasive cleaners or solvents.
7. Troubleshooting
If you experience issues with your Nuwave OxyPure ZERO E500 Air Purifier, please refer to the following common troubleshooting steps:
| Problem | Possible Cause | Solution |
|---|---|---|
| Unit does not turn on. | No power supply. | Ensure the power cord is securely plugged into a working electrical outlet. Check the circuit breaker. |
| Airflow is weak or noisy. | Filters are dirty or blocked. | Clean or wash the filters as per maintenance instructions. Ensure no obstructions are blocking air inlets or outlets. |
| Air quality does not seem to improve. | Incorrect mode selected; Room size too large; Filters need cleaning. | Ensure the unit is operating in Auto or Ultimate Clean mode. Verify the room size is within the recommended coverage area. Clean the filters. |
| Wi-Fi connection issues. | Incorrect Wi-Fi password; Unit too far from router; Router issues. | Re-enter Wi-Fi password in the app. Move the unit closer to the Wi-Fi router. Restart your router. |
For further assistance, please refer to the complete user manual or contact Nuwave customer support.
8. Specifications
Detailed technical specifications for the Nuwave OxyPure ZERO E500 Air Purifier:
| Feature | Specification |
|---|---|
| Brand | Nuwave |
| Model Number | 47351 |
| Product Dimensions | 10"D x 11"W x 18.25"H |
| Item Weight | 13.15 pounds |
| Color | White |
| Floor Area Coverage | 966 Square Feet (in 1 hour) |
| Noise Level | 21.4 dB (minimum) |
| Particle Retention Size | 0.1 Micrometer (captures 100%) |
| Controller Type | Button Control, NUWAVE CONNECT APP |
| Wattage | 48 watts |
| Special Features | 6 Fan Speeds, Auto/Eco Mode, Dual 3-Stage Filtration, Ultimate Clean Mode, ZERO Waste & ZERO Filter Replacements |
| Certifications | CARB Certified, CE Certified, ETL Certified, Energy Star Certified |
| Care Instructions | Washable & Reusable Filters |
| Assembly Required | No |
| Batteries Required | No |
9. Warranty and Support
Nuwave products are designed for quality and durability. For specific warranty information regarding your OxyPure ZERO E500 Air Purifier, please refer to the warranty card included with your product or visit the official Nuwave website.
For customer support, technical assistance, or to inquire about parts, please contact Nuwave directly. You can also find a comprehensive user manual in PDF format for download:
