1. Introduction
The ESI M4U eX is an advanced 8-port USB 3.0 MIDI interface designed for seamless integration into your music production setup. It offers versatile plug-and-play connectivity, eliminating the need for complex driver installations for basic operation. This device features dynamic configuration, automatically adapting its 8 MIDI ports for input or output, indicated by intuitive colored LEDs. Beyond its primary function, the M4U eX includes a built-in USB 3.0 hub with three connectors, consolidating your MIDI and USB devices. It is engineered for low-latency performance and precise timing, capable of standalone operation for diverse MIDI routing and merging tasks without a computer. The M4U eX is universally compatible with Windows and macOS, providing robust performance for both professional studios and live environments. An optional ESI MIDI Port driver for Windows further enhances its capabilities for complex multi-device and multi-client operations.
2. Product Overview
The ESI M4U eX is a compact and powerful MIDI interface. Below are key features and a visual guide to its components.
2.1 Key Features
- 8 Adaptable MIDI Ports: Configurable as inputs or outputs, providing extensive control for various MIDI devices.
- USB 3.0 Connectivity: Ensures high-speed data transfer and plug-and-play operation without the need for dedicated drivers.
- Integrated USB Hub: Features three additional USB 3.0 ports for connecting other USB devices, streamlining your setup.
- Standalone Functionality: Operates independently of a computer, offering flexible MIDI routing and merging capabilities with minimal latency.
- Universal Compatibility: Fully compatible with Windows and macOS operating systems.
- Intuitive LED Indicators: Colored LEDs provide visual feedback on port status (input/output).
2.2 Front Panel

2.3 Rear Panel

3. Setup
3.1 Initial Connection
- Connect the ESI M4U eX to your computer using the provided USB 3.0 cable. The device is class-compliant, meaning it should be recognized automatically by Windows and macOS without additional drivers for basic functionality.
- For standalone operation or if your computer's USB port does not provide sufficient power, connect the included DC 5V power adapter to the rear panel.
- Connect your MIDI devices (keyboards, controllers, synthesizers) to the MIDI ports on the front and rear panels. The M4U eX automatically detects whether a port is used as an input or an output, indicated by the colored LEDs.
- If using the integrated USB hub, connect your USB MIDI controllers or other USB peripherals to the three USB 3.0 ports on the rear panel.
3.2 Driver Installation (Optional for Windows)
While the M4U eX is class-compliant, an optional ESI MIDI Port driver is available for Windows users. This driver provides enhanced features for complex multi-device and multi-client operations. To install:
- Visit the official ESI website and navigate to the M4U eX product page.
- Download the latest ESI MIDI Port driver for your Windows operating system.
- Follow the on-screen instructions to complete the installation. Restart your computer if prompted.
4. Operating Instructions
4.1 Port Configuration
The M4U eX's 8 MIDI ports automatically configure as input or output based on the connected device. The LEDs next to each port indicate its current status:
- Green LED: Indicates the port is functioning as a MIDI input.
- Orange LED: Indicates the port is functioning as a MIDI output.
4.2 Standalone Mode
The M4U eX can operate without a computer, acting as a standalone MIDI router and merger. This is ideal for live setups or when you need to connect multiple MIDI devices directly.
- Ensure the M4U eX is powered via the DC 5V adapter.
- Use the "Mode" button on the front panel to cycle through different routing and merging presets. The "Status" LED will change to indicate the active mode. Refer to the full product manual for detailed descriptions of each preset.
- Connect your MIDI devices according to the desired routing. For example, you can merge multiple MIDI inputs into a single output or split one input to multiple outputs.
4.3 Using the Integrated USB Hub
The three USB 3.0 ports on the rear panel function as a standard USB hub. You can connect USB MIDI controllers, external hard drives, or other USB peripherals. When connected to a computer, these devices will be accessible through the M4U eX.
4.4 Software Integration
When connected to a computer, the M4U eX will appear as multiple MIDI input and output devices in your Digital Audio Workstation (DAW) or other music software. Select the appropriate MIDI ports for your tracks and instruments.
For Windows users with the optional ESI MIDI Port driver, you may have access to a control panel or utility for advanced routing, filtering, and configuration of MIDI messages.
4.5 Official Product Video
5. Maintenance
- Cleaning: Use a soft, dry cloth to clean the exterior of the device. Avoid using liquid cleaners or solvents.
- Storage: Store the device in a cool, dry place away from direct sunlight and extreme temperatures when not in use.
- Cable Management: Ensure all cables are connected securely and are not under strain to prevent damage to ports or cables.
- Firmware Updates: Periodically check the ESI website for any available firmware updates for your M4U eX to ensure optimal performance and access to new features.
6. Troubleshooting
- No Power/LEDs Off:
- Ensure the USB 3.0 cable is securely connected to both the M4U eX and your computer.
- If using standalone mode or experiencing power issues, verify the DC 5V power adapter is correctly connected and plugged into a working power outlet.
- Try a different USB port on your computer or a different power outlet.
- MIDI Not Transmitting/Receiving:
- Check the LED indicators on the M4U eX to confirm ports are configured correctly (green for input, orange for output).
- Verify that your MIDI cables are connected correctly (MIDI Out of device A to MIDI In of M4U eX, and MIDI Out of M4U eX to MIDI In of device B).
- In your DAW or music software, ensure the correct MIDI input/output ports for the M4U eX are selected and enabled.
- If using Windows, consider installing the optional ESI MIDI Port driver for improved compatibility and control.
- In standalone mode, cycle through the "Mode" presets to ensure the desired routing/merging configuration is active.
- USB Hub Devices Not Recognized:
- Ensure the M4U eX is receiving adequate power, especially if multiple power-hungry USB devices are connected. Use the DC 5V adapter if necessary.
- Try connecting the USB device directly to your computer to rule out issues with the device itself.
- Ensure the USB 3.0 cable connecting the M4U eX to your computer is functioning correctly.
- High Latency/Timing Issues:
- Ensure your computer's audio interface drivers are up to date and configured for optimal latency settings in your DAW.
- Close unnecessary applications running in the background on your computer.
- If using the optional Windows driver, ensure it is installed correctly.
7. Specifications
| Feature | Detail |
|---|---|
| Model Number | ESM4UEX |
| MIDI Ports | 8 (dynamically configurable as input or output) |
| Connectivity | USB 3.0 |
| USB Hub | 3 x USB 3.0 ports |
| Compatibility | Windows, macOS (Class-compliant) |
| Standalone Operation | Yes (MIDI routing and merging) |
| Power Supply | USB bus-powered or optional DC 5V adapter |
| Dimensions | 6.7 x 4.1 x 1.6 inches |
| Weight | 1 pound |
8. Warranty and Support
For warranty information and technical support, please refer to the official ESI Audio website or contact your local distributor. Keep your proof of purchase for warranty claims.
ESI Audio Website: www.esi-audio.com





