Introduction
The ASUS TUF X299 Mark 2 is an ATX motherboard designed for 7th generation LGA2066 socket Intel Core X-Series processors. It is engineered for robust 24/7 operation, offering enhanced connectivity, speed, and durability. This manual provides essential information for setting up, operating, maintaining, and troubleshooting your motherboard.
What's in the Box
Verify that all items are present in your package:
- TUF X299 Mark 2 motherboard
- Serial ATA 6Gb/s cables (4)
- SLI HB BRIDGE (2-WAY-M)
- ASUS Q-Shield
- Q-connector
- M.2 screw
- Vertical M.2 bracket set
- TUF Inside Sticker(s) (white)
- TUF Certification card
- TUF 5 Year Warranty manual (by region)
- User's manual
Setup
Follow these general steps for initial setup. Refer to the detailed User's Manual for specific instructions and diagrams.
- Prepare Your Case: Ensure your PC case is ready for an ATX motherboard installation. Install standoffs as required.
- Install CPU: Carefully open the LGA2066 socket lever, align your Intel Core X-Series processor, and gently place it into the socket. Close the lever to secure the CPU.
- Install CPU Cooler: Attach your compatible CPU cooler according to its manufacturer's instructions. Ensure proper thermal paste application.
- Install RAM: Insert DDR4 memory modules into the DIMM slots. Refer to the motherboard manual for recommended slot population for optimal performance (e.g., quad-channel configuration).
- Mount Motherboard: Carefully place the motherboard into the PC case, aligning it with the standoffs and I/O shield. Secure it with screws.
- Install Storage Devices: Install M.2 SSDs into the dual M.2 slots and SATA drives using the provided Serial ATA 6Gb/s cables.
- Install Graphics Card: Insert your graphics card into the primary PCIe slot. The Dual Patent-pending SafeSlots provide enhanced rigidity for heavyweight GPUs.
- Connect Power: Connect the 24-pin ATX power connector and the 8-pin/4-pin CPU power connectors from your power supply to the motherboard.
- Connect Peripherals: Connect front panel headers (USB, audio, power/reset buttons, LEDs) and other peripherals.
Operating
The ASUS TUF X299 Mark 2 is designed for stable and high-performance operation. Key features include:
- BIOS/UEFI: Access the UEFI BIOS for system configuration, fan control, and monitoring. The intuitive interface allows for easy adjustments.
- Thermal Radar 3: Utilize Thermal Radar 3 for customizable total system cooling and stability, especially during overclocking. This feature allows for precise fan control.
- AURA Sync RGB Lighting: Synchronize RGB lighting effects across compatible AURA Sync enabled products for a personalized aesthetic.
- Intel VROC and Optane Memory: Supports Intel Virtual RAID on CPU (VROC) and Intel Optane Memory for enhanced storage performance and responsiveness.
Maintenance
To ensure the longevity and optimal performance of your ASUS TUF X299 Mark 2 motherboard:
- Keep it Clean: Regularly clean dust from inside your PC case, especially around fans, heatsinks, and PCIe slots, using compressed air.
- BIOS Updates: Periodically check the ASUS support website for BIOS/UEFI updates. Updates can improve stability, performance, and compatibility.
- Driver Updates: Ensure all device drivers (chipset, audio, network, graphics) are up-to-date for optimal system performance and stability.
- Monitor Temperatures: Use monitoring software to keep an eye on CPU, VRM, and chipset temperatures to prevent overheating.
Troubleshooting
If you encounter issues, consider the following:
- No Power/No Boot:
- Verify all power cables (24-pin ATX, 8-pin/4-pin CPU) are securely connected.
- Check that the power supply is switched on and functioning.
- Ensure RAM modules are correctly seated in their slots. Try booting with one RAM stick.
- Display Issues:
- Confirm the graphics card is properly seated in the PCIe slot and has adequate power.
- Check monitor cable connections (HDMI, DisplayPort).
- System Instability/Crashes:
- Ensure CPU cooler is correctly installed and making good contact with the CPU.
- Check for overheating using monitoring software.
- Update BIOS and drivers to the latest versions.
- Peripheral Recognition:
- Verify USB devices are connected to the correct ports.
- Ensure necessary drivers for peripherals are installed.
Specifications
| Feature | Detail |
|---|---|
| Brand | ASUS |
| Series | TUF X299 MARK 2 |
| Model Name | TUF X299 Mark 2 |
| CPU Socket | LGA 2066 |
| Compatible Processors | Intel Core X-Series |
| Chipset Type | Intel X299 |
| RAM Memory Technology | DDR4 |
| Memory Clock Speed | 3600 MHz |
| Memory Storage Capacity | 128 GB (Max) |
| Wireless Type | 802.11ac |
| Number of USB 2.0 Ports | 1 |
| Product Dimensions | 12 x 1 x 9.6 inches |
| Item Weight | 1.5 pounds |
| Operating System | Windows 10 64-bit |
Warranty and Support
The ASUS TUF X299 Mark 2 Motherboard comes with a 5-Year Warranty, ensuring reliability and durability built on military-grade engineering.
For technical support, driver downloads, and further assistance, please visit the official ASUS support website or contact their customer service.
For additional product information, you may visit the ASUS Store on Amazon.





