Introduction
This manual provides detailed instructions for the Logitech M221 Wireless Mouse. Designed for quiet operation and reliable performance, the M221 offers a comfortable, ambidextrous design with an 18-month battery life. Please read this manual thoroughly to ensure proper setup and optimal use of your device.
Setup Guide
Follow these steps to set up your Logitech M221 Wireless Mouse:
- Install the Battery:
Locate the battery compartment on the underside of the mouse. Slide the battery cover off. Insert the included AA battery, ensuring correct polarity. Replace the battery cover.

Image: Underside view of the Logitech M221 mouse, showing the battery compartment and the location of the USB receiver.
- Locate the USB Receiver:
The tiny USB receiver is stored inside the battery compartment for convenience during transport. Carefully remove it from its slot.
- Connect the Receiver to Your Computer:
Plug the USB receiver into an available USB port on your computer (PC or Mac). The mouse will automatically connect to your computer.
- Power On the Mouse:
Ensure the power switch on the underside of the mouse is in the "ON" position. The mouse is now ready for use.
Operating Instructions
The Logitech M221 is designed for intuitive and comfortable use:
- Silent Clicking: The M221 features 90% reduced click sound, providing a quiet working environment without sacrificing the familiar click feel.
- Ambidextrous Design: Its comfortable, contoured shape is suitable for both left and right-handed users.

Image: Top view of the Logitech M221 Wireless Mouse in charcoal, alongside its compact USB receiver.
- Optical Tracking: The mouse uses 1000 DPI optical tracking for smooth and precise cursor control.
- Wireless Range: Enjoy reliable wireless connectivity up to 10 meters (33 feet) from your computer. Actual range may vary based on environmental conditions.
- Auto-Sleep Feature: To conserve battery life, the mouse automatically enters a sleep mode when not in use. Move the mouse or click a button to wake it up.
Maintenance
Proper maintenance ensures the longevity and optimal performance of your M221 mouse.
- Battery Replacement: The M221 mouse boasts an 18-month battery life. When the mouse performance degrades or the indicator light (if present) signals low battery, replace the AA battery. Refer to the "Install the Battery" step in the Setup Guide.
- Cleaning: Use a soft, dry cloth to clean the mouse. Avoid abrasive cleaners or solvents.
- Storage: When not in use for extended periods, turn off the mouse using the power switch on the underside to further conserve battery life. Store the USB receiver inside the battery compartment to prevent loss.
Troubleshooting
If you encounter issues with your Logitech M221 mouse, try the following solutions:
- Mouse Not Responding:
- Ensure the mouse is powered on.
- Check the battery. Replace it if necessary.
- Verify the USB receiver is securely plugged into a working USB port on your computer. Try a different USB port.
- Move the mouse closer to the USB receiver to rule out range issues.
- Erratic Cursor Movement:
- Clean the optical sensor on the underside of the mouse with a soft, dry cloth.
- Ensure you are using the mouse on a suitable surface. Avoid highly reflective or transparent surfaces.
- Check for interference from other wireless devices.
- Buttons or Scroll Wheel Not Working:
- Restart your computer.
- Re-insert the USB receiver.
- If the issue persists, the mouse may require replacement.
Specifications
| Feature | Detail |
|---|---|
| Brand | Logitech |
| Model | M221 (Item model number: 910-004882) |
| Connectivity Technology | 2.4 GHz Wireless (USB Receiver) |
| Movement Detection | Optical (1000 DPI) |
| Silent Buttons | Yes (90% reduced click sound) |
| Battery Type | 1 x AA Battery (included) |
| Average Battery Life | 18 Months |
| Ambidextrous Design | Yes |
| Compatible Operating Systems | Windows 10 or later, Windows 8, Windows RT, Windows 7, Mac OS X 10.5 or later, Chrome OS, Linux Kernel 2.6+2 |
| Product Dimensions | 6 x 4 x 10 cm (L x W x H) |
| Item Weight | 77 g |
| Included Components | Mouse, Nano Receiver, 1 AA Battery, User Documentation |

Image: Diagram showing the dimensions of the Logitech M221 Wireless Mouse: 99mm length, 60mm width, 39mm height, and 75g weight.
Warranty and Support
For warranty information and technical support, please refer to the official Logitech website or the documentation included with your product. Logitech provides customer support for product inquiries and assistance.
You can typically find support resources, FAQs, and contact information by visiting www.logitech.com/support.





