1. Introduction
This manual provides comprehensive instructions for the safe and effective use of Colombo Cytofex Anti Bacterial Infections 500ml. Cytofex is a specialized treatment designed to combat bacterial infections in aquatic environments, such as those affecting pond fish.

Figure 1: Colombo Cytofex Anti Bacterial Infections 500ml product packaging. The image shows a large black bottle with a green label detailing product information and a smaller retail box.
2. Important Safety Information
Always read the entire manual before using the product. Adhere to all safety guidelines to ensure the well-being of your aquatic life and yourself.
- Keep out of reach of children and pets.
- Avoid contact with skin and eyes. In case of contact, rinse immediately with plenty of water.
- Do not ingest. If swallowed, seek medical advice immediately and show this container or label.
- Use in a well-ventilated area.
- This product is for aquatic use only.
3. Product Overview
3.1 Key Features
Colombo Cytofex is formulated to effectively treat a range of bacterial infections commonly found in pond fish. Its active ingredients target specific pathogens to restore fish health.
- Effective against bacterial infections such as:
- Hole disease (Lochkrankheit)
- Fin rot (Flossenfäule)
- Skin ulcers (Ulcères)
- Mouththrush (Maulschimmel)
- Dropsy (Bauchwassersucht)
- Contains the antibiotic enrofloxacin for a wide spectrum of action.
- Includes Benzalkonium-chloride disinfectant.
- Suitable for both indoor and outdoor aquatic systems.
3.2 Product Composition
The active ingredients per milliliter include:
- Cetraria islandica extract: 600 mg/ml
- Tabebuia avellanedae extract: 300 mg/ml
- Melaleuca alternifolia extract: 300 mg/ml
4. Setup
Before administering Colombo Cytofex, ensure your pond or aquarium is prepared correctly.
- Water Quality Check: Test your water parameters (pH, ammonia, nitrite, nitrate) to ensure they are within optimal ranges for your fish species. Correct any imbalances before treatment.
- Remove Carbon Filters: If you have activated carbon or other chemical filtration media in your filter system, remove them before treatment as they can absorb the medication, reducing its effectiveness.
- Ensure Adequate Aeration: Increase aeration in the pond or tank during treatment, as some medications can reduce oxygen levels.
- Calculate Water Volume: Accurately determine the volume of water in your pond or aquarium to ensure correct dosage.
5. Operating Instructions
5.1 Dosage and Application
The recommended dosage for Colombo Cytofex is 1000 ml to treat 10,000 litres of water. This translates to a ratio of 1 ml per 10 litres of water.
| Water Volume | Cytofex Dosage |
|---|---|
| 10 Litres | 1 ml |
| 100 Litres | 10 ml |
| 1,000 Litres | 100 ml |
| 10,000 Litres | 1,000 ml (1 Litre) |
| 25,000 Litres | 2,500 ml (2.5 Litres) |
Application Steps:
- Shake the bottle well before use to ensure the solution is evenly mixed.
- Measure the required amount of Cytofex based on your pond or tank volume using a suitable measuring device.
- Dilute the measured Cytofex in a bucket of pond/tank water before adding it to the main body of water. This helps with even distribution.
- Pour the diluted solution evenly over the surface of the pond or tank.
- Observe fish behavior closely during and after treatment.
- Follow any specific instructions on the product label regarding treatment duration or repeat dosages.
6. Maintenance and Storage
Proper storage and post-treatment care are crucial for the product's efficacy and safety.
- Storage: Store Colombo Cytofex in a cool, dry place, away from direct sunlight and extreme temperatures. Ensure the cap is tightly sealed after each use.
- Post-Treatment Water Changes: After the treatment period, it is often beneficial to perform a partial water change (e.g., 25-30%) to remove residual medication and improve water quality.
- Reactivate Carbon Filters: Once the treatment is complete and any necessary water changes have been performed, you can reintroduce activated carbon or other chemical filtration media to your filter system.
7. Troubleshooting
If you encounter issues during or after treatment, consider the following common scenarios:
- No Improvement in Fish Condition:
- Verify correct dosage and water volume calculation.
- Check water parameters for underlying issues (e.g., high ammonia, nitrite).
- Ensure carbon filters or other absorbing media were removed.
- The infection might be resistant or a different type; consult an aquatic veterinarian or specialist.
- Fish Showing Stress:
- Ensure adequate aeration.
- Perform a partial water change if stress is severe.
- Check for sudden changes in water temperature or pH.
- Cloudy Water After Treatment:
- This can sometimes occur with treatments. Ensure good filtration and aeration. A partial water change may help.
If problems persist, contact a qualified aquatic professional.
8. Specifications
| Attribute | Detail |
|---|---|
| Product Name | Colombo Cytofex Anti Bacterial Infections |
| Brand | Colombo |
| Model Number | 60325 |
| Size | 500ml |
| Item Weight | 700 g |
| Package Dimensions | 11 x 2 x 1 cm |
| Special Features | Antibacterial |
| Specific Uses | Active (for treating fish diseases) |
| Indoor/Outdoor Usage | Outdoor, Indoor |
| Composition (per ml) | Cetraria islandica extract 600 mg, Tabebuia avellanedae extract 300 mg, Melaleuca alternifolia extract 300 mg |
| Treatment Capacity | 1000 ml treats 10,000 litres |
9. Warranty and Support
For information regarding product warranty, returns, or technical support, please refer to the manufacturer's official website or contact their customer service department directly. Keep your purchase receipt as proof of purchase.
Manufacturer: Colombo
For further assistance, please visit the Colombo official website or contact your local aquatic product retailer.





