1. Introduction
This manual provides essential information for the installation, operation, maintenance, and troubleshooting of your AMD MI50 graphics card. The AMD MI50 is a powerful computing accelerator designed for demanding AI inference and deep learning workloads, as well as general high-performance computing in workstations, laptops, and desktops.
Please read this manual thoroughly before using the product to ensure optimal performance and longevity.
2. Setup and Installation
Before installing the AMD MI50 graphics card, ensure your system's power supply meets the requirements and that you have an available PCI Express 2.0 X16 slot.
2.1. Unpacking
Carefully remove the graphics card and any accessories from its packaging. Inspect the card for any visible damage. The package typically includes the AMD MI50 graphics card and a cooling fan assembly.

Figure 1: AMD MI50 Graphics Card (front view)

Figure 2: AMD MI50 Graphics Card (back view)
2.2. Cooling Fan Installation
The AMD MI50 graphics card requires a dedicated cooling solution. The provided fan assembly needs to be attached to the card. Follow these steps:
- Align the cooling fan assembly with the designated mounting points on the graphics card.
- Secure the fan assembly using the provided screws. Ensure all screws are tightened evenly to prevent uneven pressure on the GPU.
- Connect the fan's power cable to the appropriate header on the graphics card.
Video 1: Demonstrates the installation of the cooling fan onto the AMD MI50 graphics card.
2.3. System Integration
- Power off your computer and disconnect all power cables.
- Open your computer case.
- Locate an available PCI Express 2.0 X16 slot on your motherboard.
- Remove any expansion slot covers that may be blocking the slot.
- Carefully insert the AMD MI50 graphics card into the PCIe slot, ensuring it is fully seated.
- Secure the graphics card to the computer case with the retaining screw or clip.
- Connect the necessary power cables from your power supply to the graphics card. The AMD MI50 typically requires two 8-pin power connectors.

Figure 3: AMD MI50 Graphics Card (end view with dual 8-pin power connectors)
- Close your computer case and reconnect all power cables.
3. Operating Instructions
3.1. Driver Installation
After physical installation, you must install the appropriate drivers for the AMD MI50 graphics card. These drivers are crucial for the operating system to recognize and utilize the card's full capabilities.
- Power on your computer.
- Download the latest drivers for the AMD MI50 from the official AMD website or your system manufacturer's support page.
- Follow the on-screen instructions to complete the driver installation. A system restart may be required.
3.2. Software Configuration
For AI inference and deep learning applications, additional software frameworks and libraries (e.g., ROCm, TensorFlow, PyTorch) may need to be installed and configured to leverage the MI50's computing power. Refer to the documentation for these specific software packages for detailed setup instructions.
4. Maintenance
Regular maintenance helps ensure the longevity and optimal performance of your AMD MI50 graphics card.
4.1. Cleaning
- Periodically clean the cooling fan and heatsink to remove dust buildup. Use compressed air to gently blow dust away from the fins and fan blades.
- Ensure the system is powered off and unplugged before performing any cleaning.
- Avoid using liquid cleaners directly on the card's components.
4.2. Thermal Management
Monitor the operating temperatures of your graphics card using system monitoring software. Ensure adequate airflow within your computer case to prevent overheating, especially during intensive computing tasks.
5. Troubleshooting
If you encounter issues with your AMD MI50 graphics card, refer to the following common troubleshooting steps:
- No Display/System Not Booting:
- Verify that the graphics card is fully seated in the PCIe slot.
- Ensure all power connectors (e.g., dual 8-pin) are securely attached to the card and the power supply.
- Test with a different display cable or monitor if possible.
- Driver Issues:
- Reinstall the latest drivers from the official AMD website.
- Ensure no conflicting graphics drivers are installed (e.g., from a previous NVIDIA card).
- Overheating:
- Check that the cooling fan is spinning correctly and is free from obstructions.
- Clean any dust from the heatsink and fan.
- Ensure your computer case has proper ventilation.
- Performance Problems:
- Verify that your software applications are configured to use the MI50 for computation.
- Check for system bottlenecks (e.g., CPU, RAM, storage).
6. Specifications
| Feature | Detail |
|---|---|
| Model | MI50 |
| Chipset Manufacturer | AMD |
| Video Memory Capacity | 16 GB (also available in 32 GB variants) |
| Video Memory Type | GDDR6 |
| Memory Interface | 4096 Bit |
| Core Clock | 1334 MHz |
| Interface Type | PCI Express 2.0 X16 |
| Outputs | DP, HDMI (Note: Some compute-focused cards may not have external display outputs) |
| Cooler Type | Fan |
| Chip Process | 80 nanometers |
| Application | Workstation, Laptop, Desktop |
| Product Status | Used |
7. Warranty and Support
For warranty information and technical support, please refer to the documentation provided by your seller or contact the manufacturer directly. Keep your proof of purchase for any warranty claims.
8. User Tips
Based on general user experiences with similar products, here are some tips for getting the most out of your AMD MI50 graphics card:
- Optimal Cooling: Given the high-performance nature of this card, ensure your system has excellent airflow and consider additional case fans if temperatures run high during heavy loads.
- Power Supply: Always use a high-quality power supply unit (PSU) with sufficient wattage and dedicated PCIe power cables to ensure stable operation.
- Software Updates: Regularly check for and install the latest AMD drivers and software framework updates (e.g., ROCm) to benefit from performance improvements and bug fixes.
- System Compatibility: Before purchasing, verify that your motherboard, CPU, and operating system are fully compatible with the AMD MI50 to avoid installation or performance issues.





