1. Introduction
The SOYO SY-B450M D4 PRO is a high-performance Micro-ATX motherboard designed for AMD Ryzen processors. It features the AMD B450 chipset, dual-channel DDR4 memory support, an AM4 socket, and M.2 NVME compatibility, offering a robust foundation for gaming, office, audio/video, and video rendering applications. This manual provides essential information for setting up, operating, and maintaining your motherboard.

2. Specifications
Below are the detailed specifications for the SOYO SY-B450M D4 PRO Motherboard:
| Feature | Description |
|---|---|
| Brand Name | SOYO |
| Chipset Manufacturer | AMD |
| Chipset | AMD B450 |
| Socket Type | AM4 |
| Processor Compatibility | AMD Ryzen 1st/2nd Generation, 3000/3000G Series, 4000/4000G Series, 5000/5000G Series Processors |
| Application | Desktop |
| Memory Type | DDR4 |
| Memory Slots | 2 (Dual Channel) |
| Maximum RAM Capacity | 64 GB |
| Supported Memory Frequencies | 2133/2400/2666/3000/3200/3400/3600MHz (OC+) |
| Storage Interface Type | SATA 3, M.2 (NVMe) |
| Number of SATA Ports | 4 |
| Number of M.2 Slots | 1 (Supports 2280/2242 form factor) |
| PCI-E Standards | PCI-E 3.0 |
| Number of PCIe x16 Slots | 1 |
| Number of PCIe x1 Slots | 1 |
| Onboard LAN | 1x RJ45 (Realtek Gigabit Ethernet Controller) |
| Audio Channels | 5.1 (Realtek 7.1 High Definition Audio Chip) |
| Back I/O Ports | 1x RJ45, HDMI 1.3, 2x USB 3.2/3.1 Gen 1, PS/2, VGA, 3-in-1 Audio Interface |
| Onboard Connectors & Header | 24-pin Main Power Connector, CPU Fan Connector(s), AAFP Connector, USB 2.0 Connector, System Panel(s) (Chassis intrusion header is inbuilt) |
| RAID Supported | Yes |
| Form Factor | Micro-ATX (180x 216 mm) |


3. Package Contents
The retail package typically includes:
- SOYO SY-B450M D4 PRO Motherboard
- I/O Shield
- SATA Cables
- User Manual (this document or similar)
- Driver CD/USB (may vary)
Note: The CR2032 battery for the CMOS will be removed before shipping due to international shipping regulations. Please install a new CR2032 battery upon receipt for proper functionality.
4. System Setup
Follow these steps to install your SOYO SY-B450M D4 PRO motherboard and components:
4.1. Motherboard Layout

4.2. Installing the CPU
- Locate the AM4 CPU socket on the motherboard.
- Lift the load lever on the side of the socket.
- Carefully align the triangular mark on your AMD Ryzen CPU with the corresponding mark on the socket.
- Gently place the CPU into the socket. Do not force it.
- Lower the load lever to secure the CPU in place.
- Install the CPU cooler according to its manufacturer's instructions.
4.3. Installing Memory (RAM)

- Locate the two DDR4 DIMM slots.
- Open the clips at both ends of the memory slot.
- Align the notch on the DDR4 memory module with the key in the DIMM slot.
- Insert the memory module firmly into the slot until the clips snap into place.
- For dual-channel performance, install memory modules in both slots.
4.4. Installing Storage Devices
4.4.1. M.2 NVMe SSD

- Locate the M.2 slot (NVME/NGFF).
- Remove the M.2 standoff screw.
- Insert the M.2 SSD into the slot at a 30-degree angle.
- Push down the SSD and secure it with the standoff screw.
4.4.2. SATA Drives
- Connect one end of the SATA data cable to a SATA 3.0 port on the motherboard.
- Connect the other end of the SATA data cable to your SATA hard drive or SSD.
- Connect a SATA power cable from your power supply unit (PSU) to the SATA drive.
4.5. Installing Expansion Cards (GPU, etc.)
- Locate the PCIe x16 slot for your graphics card or PCIe x1 slot for other expansion cards.
- Remove the corresponding slot cover from your PC case.
- Align the expansion card with the slot and press down firmly until it is seated correctly.
- Secure the card with a screw to the PC case.
4.6. Connecting Power Supply
- Connect the 24-pin ATX main power connector from your PSU to the motherboard.
- Connect the 8-pin ATX 12V power connector from your PSU to the motherboard.

4.7. Connecting Front Panel Connectors
Refer to Figure 4 for the location of the front panel headers (F_PANEL). Connect the power switch, reset switch, power LED, and HDD LED cables from your PC case to the corresponding pins on the motherboard.
4.8. Connecting I/O Ports

Connect your peripherals (monitor, keyboard, mouse, network cable, audio devices) to the appropriate ports on the rear I/O panel.
5. Operating Instructions
5.1. First Boot
After assembling your system, connect a monitor, keyboard, and mouse. Power on your system. The system should display the BIOS/UEFI splash screen. If not, check all connections.
5.2. BIOS/UEFI Setup
To enter the BIOS/UEFI setup utility, press the designated key (usually DEL or F2) during the boot process. Here you can configure system settings such as boot order, date/time, and enable/disable various features. Ensure your memory is running at its advertised speed by enabling XMP/DOCP if applicable.
5.3. Operating System Installation
Insert your operating system installation media (USB drive or DVD) and follow the on-screen instructions to install your preferred OS. After installation, install the necessary drivers for your motherboard components (chipset, LAN, audio, etc.) from the provided driver media or the SOYO website.
6. Maintenance
6.1. Cleaning
Regularly clean your PC case and motherboard to prevent dust buildup, which can lead to overheating. Use compressed air to remove dust from fans, heatsinks, and other components. Ensure the system is powered off and unplugged before cleaning.
6.2. BIOS/UEFI Updates
Periodically check the SOYO official website for BIOS/UEFI updates. Updates can improve system stability, add support for new hardware, or fix bugs. Follow the instructions provided by SOYO carefully when performing a BIOS/UEFI update to avoid damaging your motherboard.
6.3. Driver Updates
Keep your motherboard drivers (chipset, LAN, audio, etc.) updated to ensure optimal performance and compatibility with your operating system and other hardware. Download drivers from the official SOYO website.
7. Troubleshooting
- No Power/No Boot: Double-check all power connections (24-pin ATX, 8-pin CPU, GPU power). Ensure the power supply is switched on. Verify front panel connections.
- No Display: Ensure your monitor is connected to the graphics card (if dedicated) or the motherboard's video output (if using an APU). Reseat the graphics card and RAM modules.
- System Instability/Crashes: This can often be related to memory. Try running with one RAM stick at a time to identify a faulty module. Ensure RAM is seated correctly. Check CPU and GPU temperatures.
- CPU Compatibility: The motherboard supports AMD Ryzen 1st-5th generation processors. If you are using a newer Ryzen CPU (e.g., Ryzen 5 5600X), ensure your BIOS is updated to a version that supports it.
- Missing CMOS Battery: As noted in the package contents, the CR2032 battery is removed for shipping. If you experience issues with date/time or BIOS settings resetting, install a new CR2032 battery.
8. User Tips
- CPU Compatibility: This motherboard is compatible with a wide range of AMD Ryzen CPUs, including the Ryzen 5 5600X. For optimal performance with newer CPUs, ensure your BIOS is updated to the latest version.
- CMOS Battery: Remember to install a CR2032 battery for the CMOS upon receiving the motherboard, as it is removed for shipping. This ensures proper timekeeping and BIOS settings retention.
- Driver Installation: Always install the latest drivers for your chipset, LAN, and audio from the official SOYO website after installing your operating system.
9. Warranty and Support
For warranty information and technical support, please refer to the official SOYO website or contact your retailer. Keep your proof of purchase for warranty claims. SOYO provides reliable quality and customer service for its products.