Philips CT 5300: AI for End-to-End Excellence in Cardiac Imaging

Overview

The Philips CT 5300 ushers in a new era of cardiac imaging, leveraging Philips innovations and recent AI advancements to make cardiac CT more accessible. This system offers AI-enabled speed and excellence for fast, high-quality, low-dose CT cardiac exams with an intuitive workflow. Virtual Imaging tools facilitate remote collaboration, lifetime learning, and on-demand clinical support, fostering team success and clinical confidence.

Challenges in Cardiac Imaging

Cardiovascular disease remains the leading global cause of death. Coronary computed tomography angiography (coronary CTA) is the preferred noninvasive diagnostic procedure for detecting and ruling out coronary artery disease (CAD), assessing coronary anatomy and atherosclerotic plaque. Recent guidelines recommend CT as a first-line test for stable or atypical chest pain, indicating an increasing global demand for coronary CTA exams, potentially avoiding invasive procedures.

Imaging coronary arteries presents challenges due to their small caliber (approaching 1 mm), complex 3D motion during the cardiac cycle causing artifacts, and unpredictable cardiac motion from irregular heart rates. Historically, limited temporal resolution hindered artifact management, leading to non-evaluable segments and impacting diagnostic performance. Additional obstacles include staffing shortages, less experienced technologists, and a lack of familiarity with cardiac CT, often perceived as complex and requiring experienced staff.

CT 5300 is Built for Cardiac

Philips innovations and AI advances have transformed cardiac CT capabilities. The CT 5300 reimagines intelligence, delivering fast, high-quality, low-dose cardiac imaging with AI for new clinical capabilities and workflow enhancements, making routine cardiac scans easier. By bringing high-end scanner functionality to a more affordable and versatile system, Philips aims to make advanced medical technology more accessible.

Precise Image for Cardiac Scans

The CT 5300 is an intelligent system designed for clinical confidence, producing fast, routine, high-quality cardiac images even at ultra-low dose levels. This is achieved through Precise Image, an AI-based reconstruction technique utilizing a deep-learning neural network. Precise Image simultaneously reduces noise, improves image quality, and enables lower CT dose, delivering an image appearance similar to filtered back projection (FBP). Its speed is crucial for daily integration, reconstructing all reference protocols in under one minute. At 80% lower dose, Precise Image offers up to 85% lower noise and 60% better low-contrast detectability compared to conventional reconstruction. This technology makes routine cardiac imaging feasible without prior dose concerns.

Example Scan Parameters: 80 kVp, 192 mAs, CTDIvol 5.78 mGy, DLP 71.64 mGy*cm, resulting in an effective dose of 1 mSv (k=0.014).

NanoPanel Precise Detector: The First Detector Made for AI Reconstruction

The CT 5300 features the NanoPanel Precise detector, engineered specifically for AI-based reconstruction. Unlike conventional detectors not designed for extremely low dose levels, NanoPanel Precise leverages Precise Image capabilities to deliver high-quality images at significantly lower radiation doses, free from electronic noise or artifacts common with older detectors at similar low doses.

NanoPanel Precise is Made for AI: Its application-specific integrated circuit (ASIC) design reduces artifacts inherent in low-dose imaging, decreasing noise by up to 19%.

Precise Cardiac Corrects for Coronary Artery Motion

Precise Cardiac is a novel, zero-click technique that compensates for cardiac motion, enhancing the visualization of coronary arteries during CT imaging. This results in a 6x gain in effective temporal resolution for the CT 5300, achieving an effective temporal resolution as low as 29.2 ms.

How Motion-Corrected Images Are Generated: Applicable to both prospective (axial) and retrospective (helical) gated coronary CTA exams, Precise Cardiac employs efficient filtering techniques around the targeted cardiac phase. It identifies and dynamically tracks object motion within the cardiac cycle, generating motion-corrected images in the projection domain by accounting for structural displacement during back-projection.

Precise Cardiac Processing Steps:

Standard Cardiac Processing Pipeline: Involves Scan, Sinogram data with EKG strip, Target phase, Back projection, and Motion-corrected image.
Precise Cardiac Processing Pipeline: Incorporates Phase neighbor range, Target phase, and uses Elastic registration, motion estimation, and correction (MVF - Motion Vector Field) to describe heart motion around a target phase.

No Manual Intervention Needed: Precise Cardiac is integrated into the CT console workflow, eliminating the need for manual intervention, data transfer, or additional workstations. It can improve coronary CTA assessment by reducing motion artifacts, particularly in patients with elevated heart rates, potentially salvaging nondiagnostic segments and increasing diagnostic confidence, thereby reducing the need for repeat scans.

Benefits of Precise Cardiac:

Offers 6x gain in effective temporal resolution, down to 29.2 ms. [motion compensation icon]
Removes motion artifacts for rapidly moving coronaries, producing images comparable to zero motion.
Improves coronary CTA assessment by reducing motion artifacts, especially for those with elevated heart rates.

AI-Enabled Cardiac Scanning: Every Step of the Way

Philips AI-enabled advances enhance precision in dose, speed, image quality, and workflow from scan preparation through reconstruction.

CT Smart Workflow for End-to-End Excellence:

Prepare: Precise Position (improves patient positioning accuracy and consistency by up to 50% vertically, up to 70% consistency, reduces time by up to 23%), Precise Planning (automatic plan box positioning).
Scan: Prospective and retrospective ECG-gated cardiac scanning, Automatic arrhythmia detection, ECG editing for abnormal beats.
Reconstruct: Precise Cardiac (enhances effective temporal resolution, mitigates motion artifacts), Precise Image (high image quality at low dose).
Post-process: TAVI Planning and Advanced Vessel Analysis, Choice of on-console or advanced visualization workspace, Comprehensive Cardiac Analysis, CT Calcium Scoring.

Successful cardiac scanning is enhanced by a smooth workflow for quick, confident clinical decisions.

ECG at the Gantry: ECG is embedded in the gantry, eliminating the need for an extra monitor and freeing space.

Stay Closer to the Patient: OnPlan patient-side touchscreen controls allow technologists to manage more directly from the scanner, minimizing time away from anxious patients. These controls offer an intuitive workflow, aid in lead placement with ECG diagrams, guide patients through breathing patterns, and display real-time heart rate.

Cardiac DoseRight: Reduces tube output outside of desired cardiac phases in retrospective gated scans by up to 50% (depending on heart rate), suggesting average tube current based on patient size and DRI setting.

Empower Your Cardiac Imaging Team

Cardiac exams require specialized expertise. Philips addresses this complexity with streamlined workflows and Virtual Imaging tools to enhance staff competence and confidence. The CT 5300 provides tools for remote consultation, expert training, and clinical support.

CT Collaboration Live: Extends team capabilities with remote connectivity for voice and video calls from the scanner, allowing remote viewing and interaction with the console screen for simplified consultation and training.

Lifecycle Learning: Offers instructor-led online training and on-demand content to build staff proficiency for cardiac scanning, enabling remote application training for less experienced staff across multiple locations.

On Demand Clinical Support: Provides real-time access to Philips experts via CT Collaboration Live for assistance when needed, easing the integration of skills for teams new to cardiac scanning.

Ambient Experience: Creates a welcoming environment with dynamic lighting, video projection, and sound, chosen by the patient, to provide a positive distraction. Visual cues support breathing guidance, leading to better patient compliance, fewer delays, and retakes. Studies show significant patient satisfaction increases and positive impact on patients and staff.

Clinical Case Studies

Precise Image: Provides excellent image quality at low dose. Example Scan Parameters: 120kVp, 99 mAs, CTDIvol 12.03 mGy, DLP 161.81 mGy*cm, effective dose 2.26 mSv (k=0.014).

Precise Image Sharpness Levels: Offers excellent image quality with adjustable sharpness. Example Scan Parameters: 100 kVp, 246 mAs, CTDIvol 11.92 mGy, DLP 222 mGy*cm, effective dose 3 mSv (k=0.014) for retrospectively gated coronary CTA.

Precise Cardiac: Helps salvage nondiagnostic scans by resolving motion artifacts. The right coronary artery (RCA), which shows significant motion without Precise Cardiac, becomes motion-free and diagnostic with its use.

Detailed Insights Through Easy Post-Processing and Analysis of Images

Perform post-processing and analysis on the CT console or a dedicated advanced visualization workstation powered by AI.

CT Coronary Calcium Scoring: Provides one-click 3D segmentation and quantification of coronary artery calcifications using automatic CT number calculations in user-defined regions, based on MESA database parameters. It aids in assessing coronary artery calcium burden as a prognostic indicator of morbidity and mortality risk from atherosclerotic coronary artery disease. Available on console and as Heartbeat CS on the Advanced Visualization Workstation.

CT Comprehensive Cardiac Artery Analysis: Offers tools for dimensional and quantitative measurements of coronary arteries. It features automatic 3D model-based whole-heart segmentation and zero-click coronary artery segmentation, enabling automatic extraction and visualization of the entire coronary tree. It visualizes vessel lumen via morphological analysis, analyzes free lumen diameter, performs functional analysis of ventricles, and assesses chambers and valve morphology in 3D and dynamic cine modes. Findings can be reported in a standardized manner following CAD-RADS guidelines. This enables objective, quantifiable diagnosis, even for complex cases, supporting noninvasive treatment paths. Available on console and Comprehensive Cardiac Analysis on the Advanced Visualization Workstation.

CT Cardiac Plaque Assessment: Enables cross-sectional measurements along coronary arteries and automatically calculates regional and global quantities of plaque volume.

Conclusion

This new era of cardiac imaging leverages AI across every step of the exam process for end-to-end excellence. The CT 5300 makes cardiac CT scanning more accessible by enabling facilities to offer AI-driven advances for fast, high-quality, low-dose CT with an easy-to-learn and use workflow. Virtual Imaging tools provide ongoing support for clinical teams, leveraging experience and addressing staffing challenges. These capabilities facilitate successful cardiac scanning and are vital for meeting the increasing demand for cardiac CT.

References

Di Cesare M, Perel P, Taylor S, et al. The Heart of the World. Glob Heart. 2024 Jan 25;19(1):11. doi: 10.5334/gh.1288. PMID: 38273998; PMCID: PMC10809869
Moss AJ, Williams MC, Newby DE, Nicol ED. The Updated NICE Guidelines: Cardiac CT as the First-Line Test for Coronary Artery Disease. Curr Cardiovasc Imaging Rep. 2017;10(5):15. doi: 10.1007/s12410-017-9412-6. Epub 2017 Mar 27. PMID: 28446943; PMCID: PMC5368205.
Knuuti J, Wijns W, Saraste A, et al. 2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes: The Task Force for the diagnosis and management of chronic coronary syndromes of the European Society of Cardiology (ESC), European Heart Journal. 2020;41(3):407–477. https://doi.org/10.1093/eurheartj/ehz425
Gulati M, Levy PD, Mukherjee D, et al. 2021 AHA/ACC/ASE/CHEST/SAEM/SCCT/SCMR Guideline for the Evaluation and Diagnosis of Chest Pain: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines. Circulation. 2021;144(22):e368-e454. doi: 10.1161/CIR.0000000000001029. Epub 2021 Oct 28. Erratum in: Circulation. 2021 Nov 30;144(22):e455. Erratum in: Circulation. 2023 Dec 12;148(24):e281. PMID: 34709879.
Husmann L, Leschka S, Desbiolles L, et al. Coronary artery motion and cardiac phases: dependency on heart rate— implications for CT image reconstruction. Radiology. 2007;245:2:567-576.
Ambient Experience installed base study 2020.
Study conducted by Marjolein van der Zwaag in collaboration with Harm Geraedts from Jeroen Bosch Hospital, ‘s-Hertogenbosch, the Netherlands, Philips Research Laboratories Europe, Nov/Dec 2011.

Results from case studies are not predictive of results in other cases. Results in other cases may vary.

© 2024 Koninklijke Philips N.V. All rights reserved. Specifications are subject to change without notice. Trademarks are the property of Koninklijke Philips N.V. or their respective owners. 4522 991 87191 * AUG 2024

How to reach us: Please visit www.philips.com

	Philips CT 5300: Advanced Computed Tomography System Specifications Detailed specifications for the Philips CT 5300 Computed Tomography system, covering its advanced features, imaging capabilities, dose management, clinical enhancements, networking, and site planning requirements.
	Philips Incisive CT Software Upgrade Enhances Cardiovascular Care at Nagano-Chuo Hospital Discover how Nagano-Chuo Hospital upgraded their Philips Incisive CT system with V5.1 software to improve cardiovascular imaging, reduce costs, and enhance diagnostic accuracy, leveraging advanced features like Precise Cardiac and AI-enabled Precise Image.
	Philips CT Rembra RT/CT Areta RT Technical Reference Guide Detailed technical reference guide for Philips CT Rembra RT and CT Areta RT systems, covering operation, safety, performance, and maintenance.
	FieldStrength Magazine: Philips MRI Innovations - BlueSeal & SmartSpeed AI Explore the latest in Philips MRI technology with FieldStrength Issue 60. Featuring BlueSeal's helium-free operation for cost savings and operational simplicity, and AI-powered SmartSpeed for enhanced speed, precision, and diagnostic capabilities. Discover user experiences and educational insights from leading healthcare professionals.
	Philips SmartSpeed: Advanced MR Imaging for Uncompromised Image Quality and Speed Philips SmartSpeed is an advanced MR clinical application leveraging AI and Compressed SENSE for unparalleled image quality, faster scans, improved productivity, and enhanced patient accessibility in diagnostic imaging.
	Philips Azurion Cathlab: Seamless CCTA Data Integration for Image-Guided Therapy Discover how Philips Azurion cathlab integrates with the Advanced Visualization Workspace to seamlessly synchronize CCTA data, enhancing image-guided therapy and PCI procedures.
	Philips Circular Equipment: Refurbished & Pre-Owned Medical Systems for Healthcare Explore Philips Circular Equipment, a sustainable and cost-effective solution for high-quality refurbished and pre-owned medical imaging systems. Enhance patient care while meeting budget and environmental goals.
	Philips Advanced Visualization Workspace: Spectral Applications User Guide Explore the capabilities of the Philips Advanced Visualization Workspace with its Spectral Applications. This guide provides comprehensive information for medical professionals on visualizing, analyzing, and interpreting advanced spectral CT datasets for enhanced diagnostic confidence.