Molecular Interactions: Metal Ions and Protein Chaperones in the Urease System from Helicobacter pylori

Research Overview

This doctoral research investigates the intricate molecular interactions that govern the urease system in Helicobacter pylori. The study focuses on the roles of metal ions and protein chaperones in mediating these interactions, exploring aspects of protein-protein binding, metal homeostasis, and the functional mechanisms of urease and hydrogenase enzymes.

The research encompasses experimental procedures such as protein cloning, expression, purification, and biochemical characterization, alongside computational methods for structural modeling and analysis of protein complexes.