Introduction
This manual provides essential information for setting up, operating, maintaining, and troubleshooting your Lenovo ThinkCentre M75s Gen 2 Desktop Computer. Please read this manual thoroughly before using your computer to ensure proper operation and to maximize its lifespan.
What's in the Box
Verify that all items are present in the packaging:
- ThinkCentre M75s Gen 2 11R8001XUS Desktop Computer
- USB Traditional Keyboard
- USB Calliope Mouse
- Stand
Product Overview
Familiarize yourself with the physical components of your ThinkCentre M75s Gen 2 desktop computer.

Figure 1: Angled front view of the Lenovo ThinkCentre M75s Gen 2 desktop computer, showcasing its compact design and front panel ports.

Figure 2: Straight front view of the desktop computer, highlighting the optical drive, power button, and front USB ports.

Figure 3: Another angled front view, providing a clear perspective of the ventilation grilles and the Lenovo branding.

Figure 4: Rear view of the desktop computer, showing the various input/output ports including display outputs, USB ports, and the power connector.

Figure 5: Left side view of the computer chassis, illustrating its compact form factor.

Figure 6: Right side view of the computer chassis, showing the ventilation design.

Figure 7: The ThinkCentre M75s Gen 2 desktop computer shown in a dual monitor setup, demonstrating its multi-display capability.

Figure 8: The ThinkCentre M75s Gen 2 desktop computer displayed with a single monitor, keyboard, and mouse, illustrating a typical workstation configuration.
Setup Instructions
- Unpack the Computer: Carefully remove the desktop computer and all accessories from the packaging. Place the computer on a stable, flat surface.
- Connect the Monitor: Connect your monitor to one of the available display ports on the rear of the computer (e.g., HDMI, DisplayPort). Ensure the connection is secure.
- Connect Peripherals:
- Connect the USB keyboard to an available USB port.
- Connect the USB mouse to another available USB port.
- If using wired internet, connect an Ethernet cable to the network port.
- Connect Power: Plug the power cord into the power connector on the rear of the computer, then plug the other end into a grounded electrical outlet.
- Power On: Press the power button located on the front of the computer. The system will begin to boot up.
- Initial Setup: Follow the on-screen instructions to complete the Windows 11 Pro operating system setup, including language, region, network connection, and user account creation.
Operating Instructions
Your Lenovo ThinkCentre M75s Gen 2 comes pre-installed with Windows 11 Pro, providing a robust platform for various applications. The AMD Ryzen 5 PRO 5650G processor, 8GB DDR4 RAM, and 256GB NVMe SSD ensure efficient performance for daily tasks and multitasking.
- Power On/Off: Press the power button to turn the computer on. To shut down, click the Start button in Windows, then select Power > Shut down.
- Using the Optical Drive: The integrated DVD-Writer supports reading and writing of DVDs and CDs. Press the eject button on the drive to open the tray, insert your disc, and close the tray.
- Connecting to Bluetooth Devices: Your computer supports Bluetooth connectivity. To pair a device, go to Windows Settings > Bluetooth & devices, and follow the instructions to add a new device.
- Display Connectivity: Utilize the HDMI and DisplayPort outputs for connecting to monitors. The system supports multiple displays for enhanced productivity.
- USB Ports: Connect USB devices such as external drives, printers, or other peripherals to the available USB 2.0 and USB 3.2 Gen 1 ports.
Maintenance
Regular maintenance helps ensure the longevity and optimal performance of your computer.
- Keep it Clean: Regularly clean the exterior of the computer with a soft, dry cloth. Use compressed air to clear dust from ventilation grilles to prevent overheating.
- Software Updates: Keep your Windows 11 Pro operating system and drivers updated. This ensures security and performance improvements.
- Data Backup: Periodically back up important data to an external drive or cloud storage to prevent data loss.
- Physical Security: Utilize the integrated security slot to physically secure your computer, if desired.
Troubleshooting
If you encounter issues with your computer, refer to the following common troubleshooting steps:
- No Power:
- Ensure the power cord is securely connected to both the computer and the electrical outlet.
- Verify the power outlet is functional by plugging in another device.
- No Display:
- Check that the monitor is powered on and the video cable (HDMI, DisplayPort) is securely connected to both the computer and the monitor.
- Try connecting the monitor to a different display port on the computer, if available.
- Peripherals Not Responding:
- Ensure USB devices (keyboard, mouse) are properly connected to the USB ports.
- Try connecting the device to a different USB port.
- Restart the computer.
- Slow Performance:
- Close unnecessary applications running in the background.
- Ensure your operating system and drivers are up to date.
- Check for malware or viruses using reputable security software.
For further assistance, please refer to the Lenovo support website or contact their customer service.
Specifications
| Feature | Detail |
|---|---|
| Brand | Lenovo |
| Series | ThinkCentre M75s Gen 2 |
| Model Number | 11R8001XUS |
| Operating System | Windows 11 Pro |
| Processor | AMD Ryzen 5 PRO 5650G Hexa-core 3.90 GHz |
| RAM | 8 GB DDR4 SDRAM |
| Storage | 256 GB NVMe SSD |
| Graphics Coprocessor | AMD Radeon Graphics (Integrated) |
| Optical Drive | DVD-Writer |
| Wireless Type | Bluetooth |
| USB 2.0 Ports | 4 |
| Display Outputs | HDMI, DisplayPort |
| Max Screen Resolution | 3840 x 2160 |
| Form Factor | Small Form Factor (SFF) |
| Item Weight | 11.7 pounds |
| Product Dimensions (LxWxH) | 0.5 x 0.1 x 0.5 inches (Note: These dimensions seem incorrect for a desktop tower, likely a data entry error in source. Refer to manufacturer's official site for accurate dimensions.) |
Warranty and Support
For warranty information, technical support, and service inquiries, please refer to the official Lenovo website or contact Lenovo customer support directly. Keep your purchase receipt and product serial number (found on the device) handy when contacting support.
You can typically find support resources, drivers, and contact information on the official Lenovo support portal: support.lenovo.com





