Product Overview
The ASUS ROG Strix B650E-E Gaming WiFi motherboard is designed to elevate your PC build with cutting-edge features and robust performance. It supports AMD Ryzen Desktop 9000*, 8000*, and 7000 Series Processors, offering future-proof compatibility and powerful capabilities for gaming and demanding applications.
*BIOS Update may be required when used with AMD Ryzen Desktop 9000 and 8000 Series CPU Processors.

Figure 1: ASUS ROG Strix B650E-E Gaming WiFi Motherboard and its retail packaging.
Key Features
- AM5 Socket: Ready for AMD Ryzen Desktop 9000*, 8000*, and 7000 Series Processors.
- Robust Power Solution: 16 + 2 teamed power stages with dual ProCool power connectors, high-quality alloy chokes, and durable capacitors for multi-core processors.
- Optimized VRM Thermals: Massive heatsinks with strategically cut airflow channels and high conductivity thermal pads.
- Next-Gen M.2 Support: Two PCIe 5.0 M.2 slots and two PCIe 4.0 M.2 slots, all with heatsinks for maximized performance.
- Abundant Connectivity: USB 3.2 Gen 2x2 Type-C port, eleven additional USB ports, two PCIe 5.0 x16 SafeSlots, HDMI 2.1, and DisplayPort 1.4.
- High-Performance Networking: On-board WiFi 6E (802.11ax), Bluetooth 5.2, and Intel 2.5G Ethernet with ASUS LANGuard.
- Intelligent Control: ASUS-exclusive AI Networking and Two-Way AI Noise Cancelation.
- Immersive Gaming Audio: ALC4080 with Savitech SV3H712 amplifier, DTS Sound Unbound, and Sonic Studio III.
- Unmatched Personalization: ASUS-exclusive Aura Sync RGB lighting, including one RGB header and three addressable Gen 2 headers.
What's in the Box
The ASUS ROG Strix B650E-E Gaming WiFi Motherboard package includes the following components:

Figure 2: Unboxed components of the ASUS ROG Strix B650E-E Gaming WiFi Motherboard.
- ASUS ROG Strix B650E-E Gaming WiFi Motherboard
- User Manual
- WiFi 6E Antenna
- ROG Strix Stickers
- Thank You Card
- SATA Cables
- ROG Keychain
- Spare M.2 Thermal Pad
Setup and Installation
Before beginning installation, ensure your system is powered off and unplugged from the wall outlet. Always handle the motherboard by its edges to prevent static discharge damage.
1. Motherboard Placement
Carefully align the motherboard with the standoffs in your PC case. Ensure all screw holes match before gently lowering the motherboard into place. Secure it with the appropriate screws.
2. CPU Installation
Open the CPU socket lever. Align the triangular mark on the CPU with the mark on the socket. Gently place the CPU into the socket without forcing it. Close the lever to secure the CPU.
Video 1: Product Overview showing the motherboard and its features, including a brief demonstration of handling.
3. RAM Installation
Open the clips on the DDR5 DIMM slots. Align the notch on the RAM module with the notch in the slot. Press down firmly on both ends of the RAM module until the clips snap into place.
4. M.2 SSD Installation
Remove the M.2 heatsink from the desired slot. Insert the M.2 SSD into the slot at an angle, then gently push it down. Secure it with the provided M.2 screw or Q-Latch mechanism. Reattach the heatsink.

Figure 3: Motherboard layout highlighting expansion slots and M.2 slots for storage and add-in cards.
5. Graphics Card (GPU) Installation
Open the PCIe 5.0 x16 SafeSlot latch. Align your graphics card with the slot and press down firmly until it clicks into place. Secure the card to the case with screws. Connect necessary PCIe power cables from your power supply.
6. Power Supply Connections
Connect the 24-pin ATX power connector and the 8-pin + 4-pin (or dual 8-pin) CPU power connectors to the motherboard. Connect SATA power cables to your storage drives and other peripherals.
7. Front Panel Connections
Connect the front panel headers (power button, reset button, USB ports, audio jacks) to their respective pins on the motherboard. Refer to the motherboard's detailed manual for exact pin layouts.

Figure 4: Detailed view of the motherboard's rear I/O panel, showing USB, audio, video, and network ports.
Operating Instructions
1. Initial Boot and BIOS Setup
After assembling your PC, connect a monitor, keyboard, and mouse. Power on the system. Press the DEL or F2 key during startup to enter the BIOS (UEFI) setup utility. Here you can configure boot order, enable XMP/EXPO for RAM, and adjust other system settings.
2. Driver Installation
Once the operating system is installed, install the latest drivers for your motherboard's chipset, LAN, Wi-Fi, audio, and other components. These can be found on the ASUS support website for your specific model.
3. Software Utilities
ASUS provides various software utilities to enhance your experience, such as Armoury Crate for Aura Sync RGB control and system monitoring, and AI Suite 3 for system tuning and fan control.
Maintenance
1. Keeping Your System Clean
Regularly clean dust from your PC case, fans, and heatsinks using compressed air. Ensure proper airflow to prevent overheating, especially for the VRM and chipset areas.

Figure 5: Thermal management components on the motherboard, including VRM, M.2, and chipset heatsinks.
2. BIOS Updates
Periodically check the ASUS support website for BIOS updates. BIOS updates can improve system stability, add support for new CPUs or features, and fix bugs. Follow the instructions provided by ASUS carefully when updating the BIOS.
3. Driver Updates
Keep your drivers updated to ensure optimal performance and compatibility with new software and hardware. Use the ASUS support website or Armoury Crate for convenient driver management.
Troubleshooting
1. No Display/POST Issues
- Check Power Connections: Ensure all power cables (24-pin ATX, CPU, GPU) are securely connected.
- Reseat Components: Try reseating RAM modules, graphics card, and M.2 SSDs.
- Clear CMOS: Use the Clear CMOS button on the rear I/O panel or short the CLRTC pins on the motherboard to reset BIOS settings.
- BIOS FlashBack: If the system doesn't POST after a CPU or RAM upgrade, use the BIOS FlashBack feature to update the BIOS without a CPU or RAM installed. Refer to the detailed manual for instructions.
2. System Instability/Crashes
- Check Temperatures: Monitor CPU, GPU, and chipset temperatures using monitoring software. Ensure adequate cooling.
- Update Drivers/BIOS: Outdated drivers or BIOS can cause instability.
- Test RAM: Run memory diagnostic tools to check for faulty RAM modules.
- Power Supply: Ensure your power supply unit (PSU) has sufficient wattage for all components.
3. Network/Wi-Fi Issues
- Install Latest Drivers: Ensure LAN and Wi-Fi drivers are up to date.
- Check Antenna: For Wi-Fi, ensure the antenna is securely connected.
- Router/Modem: Restart your network equipment.
Specifications
| Feature | Detail |
|---|---|
| Brand | ASUS |
| Model Name | ROG STRIX B650E-E GAMING WIFI |
| CPU Socket | Socket AM5 |
| Chipset Type | AMD B650 |
| RAM Memory Technology | DDR5 |
| Memory Speed | 6400 MHz |
| Max Memory Capacity | 128 GB |
| PCIe Support | PCIe 5.0 (2x x16 SafeSlots) |
| M.2 Slots | 2x PCIe 5.0 M.2, 2x PCIe 4.0 M.2 |
| Wireless Type | WiFi 6E (802.11ax), Bluetooth 5.2 |
| LAN | Intel 2.5G Ethernet |
| USB Ports | USB 3.2 Gen 2x2 Type-C, USB 3.2 Gen 2, USB 2.0 |
| Video Outputs | HDMI 2.1, DisplayPort 1.4 |
| Audio | ALC4080 with Savitech SV3H712 amplifier |
| Dimensions (LxWxH) | 10.9 x 3.1 x 13.5 inches |
| Item Weight | 5 pounds |
Official Product Videos
ASUS ROG Strix B650E-E Gaming WiFi Motherboard Overview
This video provides a comprehensive overview of the ASUS ROG Strix B650E-E Gaming WiFi Motherboard, showcasing its design, key features, and connectivity options. It highlights the robust power solution, next-gen M.2 support, and advanced thermal controls.
ROG Strix B650E-E Gaming WiFi Etail Video
This video focuses on the retail aspects and highlights of the ROG Strix B650E-E Gaming WiFi Motherboard, emphasizing its performance capabilities and design for gaming enthusiasts.
Warranty and Support
For warranty information, technical support, and driver downloads, please visit the official ASUS support website. You can also refer to the full User Manual (PDF) for detailed instructions and troubleshooting guides.
User Manual (PDF): Download Here
ASUS Support: Visit ASUS Support Website





