1. Introduction
This manual provides essential information for setting up, operating, maintaining, and troubleshooting your XP-Pen Artist 22 2nd Generation Pen Display. Please read it thoroughly to ensure optimal performance and longevity of your device.

Image 1.1: The XP-Pen Artist 22 2nd Generation Pen Display, showcasing its large screen.
2. What's in the Box
Verify that all items listed below are included in your package:
- 1 x 21.5” Graphics Display
- 1 x PA6 Battery-free Stylus
- 1 x Pen Holder (comes with 8 pen nibs)
- 1 x USB-C to USB-C Cable
- 1 x USB-A to USB-C Cable
- 1 x HDMI Cable
- 1 x Power Adapter
- 1 x Power Cord
- 1 x Quick Guide
- 1 x Cleaning Cloth
- 1 x Black Drawing Glove

Image 2.1: All included accessories and the pen display.
3. Setup Guide
Follow these steps to set up your XP-Pen Artist 22 2nd Generation Pen Display:
3.1. Physical Connection
- Power Connection: Connect the power adapter to the display and plug it into a power outlet.
- Data & Display Connection:
- USB-C to USB-C (Full-featured): If your computer (iMac, MacBook Pro, or Windows computer) supports a full-featured USB-C port, use the provided USB-C to USB-C cable for both data and display.
- HDMI & USB-A to USB-C: If your computer does not support full-featured USB-C, use the HDMI cable for video output and the USB-A to USB-C cable for data transmission.
- Adjustable Stand: Adjust the integrated stand to your preferred working angle (16 to 90 degrees) for comfortable use. The cable slot and detachable back cover help keep cables organized.

Image 3.1: Diagram illustrating USB-C to USB-C and HDMI/USB-A to USB-C connection methods.

Image 3.2: The adjustable stand allows for angles from 16 to 90 degrees, with integrated cable management.
3.2. Driver Installation
Before using the pen display, download and install the latest drivers from the official XP-Pen website. Ensure any previous tablet drivers are uninstalled to prevent conflicts.
4. Operating Instructions
The XP-Pen Artist 22 2nd Generation is designed for intuitive and precise creative work.
4.1. Display Features
- Screen Size: 21.5-inch display.
- Resolution: 1920x1080 Full HD.
- Color Gamut: 86% NTSC (Adobe RGB≥90%, sRGB≥122%) for vibrant and accurate colors.
- Accuracy: Enhanced cursor positioning, even at screen corners, for a satisfying drawing experience.

Image 4.1: Visual representation of the 21.5-inch screen, 1080p resolution, and sRGB color accuracy.
4.2. Stylus Usage
The included PA6 Battery-free Stylus offers advanced performance:
- Pressure Sensitivity: 8,192 levels of pressure sensitivity for fine control over line thickness and opacity.
- Tilt Function: Supports up to 60 degrees of tilt function, allowing for natural shading and brush effects.
- Battery-Free: No charging required for the stylus.

Image 4.2: Illustration of the stylus's 8,192 pressure levels and tilt function.
4.3. Software Compatibility
The Artist 22 2nd Generation is compatible with a wide range of operating systems and digital art software:
- Operating Systems: Windows 10/8/7, Mac OS X 10.10 (and higher), and Linux.
- Software: Compatible with popular applications such as Adobe Photoshop, Illustrator, SAI, CDR, GIMP, Krita, MediBang, FireAlpaca, and Blender3D.

Image 4.3: Icons representing various compatible operating systems and creative software.
4.4. Extended Functionality
- Online Teaching & Remote Work: Ideal for digital drawing, painting, sketching, e-signatures, online teaching, and remote work. It is compatible with Microsoft Office apps like Word, PowerPoint, OneNote, Zoom, and Xsplit.
- Android Device Projection: Connect your full-featured USB-C supported Android phone to the Artist 22 2nd Generation to project your phone screen onto the larger display for viewing shows, playing games, or listening to music.

Image 4.4: A user connecting an Android phone to the display to project content.
Video 4.1: An overview of the XP-Pen Artist 22 2nd Generation, demonstrating its features and applications in creative work and daily use.
5. Maintenance
Proper maintenance ensures the longevity and optimal performance of your pen display:
- Cleaning: Use the provided cleaning cloth or a soft, lint-free cloth to gently wipe the screen and body. Avoid abrasive cleaners or solvents.
- Storage: When not in use, store the display in a clean, dry environment away from direct sunlight and extreme temperatures.
- Stylus Nibs: Replace stylus nibs when they show significant wear to maintain drawing precision. Extra nibs are included in the pen holder.
- Cable Management: Utilize the cable slot and detachable back cover to keep cables tidy and prevent damage.
6. Troubleshooting
If you encounter issues with your XP-Pen Artist 22 2nd Generation, refer to the following common solutions:
- No Display/Signal:
- Ensure all cables (power, USB-C, HDMI) are securely connected.
- Verify your computer's display settings are configured to extend or duplicate the display.
- If using HDMI, ensure the USB-A to USB-C cable is also connected for data.
- Stylus Not Working/No Pressure:
- Check if the driver is correctly installed and updated. Reinstall if necessary.
- Ensure the stylus nib is properly inserted.
- Test the stylus in different compatible software applications.
- Inaccurate Cursor:
- Recalibrate the screen and stylus in the XP-Pen driver settings.
- Ensure there are no magnetic interferences near the display.
- Software Conflicts: Uninstall any other tablet drivers before installing the XP-Pen driver.
For further assistance, please contact XP-Pen customer support.
7. Specifications
| Feature | Detail |
|---|---|
| Product Dimensions | 23.4 x 5.5 x 16.5 inches |
| Item Weight | 19.06 pounds |
| Item Model Number | ArtistCD220F_US |
| Connectivity Technology | HDMI, USB |
| Pressure Sensitivity | 8192 Levels |
| Operating System Compatibility | Windows 7 and above, Mac OS X 10.10 (and higher), and Linux |
| Special Feature | Drawing/learning/working |
| Date First Available | March 2, 2022 |
8. Warranty and Support
8.1. Warranty Information
XP-Pen offers a 1-Year Protection Plan for all XP-Pen products. During this limited protection period, XP-Pen will repair or replace, at XP-Pen's sole option, any parts of the product that are defective or malfunctioning during normal usage. Please contact XP-Pen directly for specific terms and conditions regarding support, returns, and refunds.
8.2. Customer Support
If you have any questions about the product or require technical assistance, you can get in touch with XP-Pen via Amazon Message or through their official website. Please refer to the Quick Guide included in your package for additional contact details.





