1. Introduction
This manual provides detailed instructions for the installation, operation, and maintenance of your ASUS ROG Strix Z390-F Gaming Motherboard. Designed for 8th and 9th Generation Intel Core processors, this ATX motherboard offers robust performance and extensive connectivity for gaming enthusiasts. Key features include Dual M.2 slots, USB 3.1 Gen 2, Gigabit LAN, and ASUS OptiMem II for enhanced DDR4 memory stability.

Image 1.1: ASUS ROG Strix Z390-F Gaming Motherboard and its retail packaging.
2. What's in the Box
Verify that all components listed below are present in your motherboard package:
- ROG STRIX Z390-F GAMING Motherboard
- Support DVD
- User guide
- 2-in-1 SATA 6Gb/s cables (2)
- SLI™ HB Bridge (2-WAY-M)
- Extension Cable for RGB Strips (80cm)
- Extension Cable for Addressable LED Strips (80cm)
- Fan bracket
- M.2 Screw Package
- ROG Strix door hanger
- ROG Strix Thank you card
- ROG Strix series sticker

Image 2.1: All items included in the ASUS ROG Strix Z390-F Gaming Motherboard package.
3. Product Overview
Familiarize yourself with the layout and key components of your motherboard.
3.1. Motherboard Layout

Image 3.1: Overview of the motherboard highlighting key components such as the CPU socket, DIMM slots, PCIe slots, and M.2 slots.
3.2. Rear I/O Panel
The rear I/O panel provides various ports for connecting external devices.

Image 3.2: The rear I/O panel featuring PS/2, USB 2.0, USB 3.1 Gen2 (Type-A and Type-C), DisplayPort, HDMI, Gigabit LAN, and 8-Channel HD Audio ports.
4. Setup and Installation
Follow these steps for proper installation of your motherboard and components. Always ensure your system is powered off and unplugged before handling internal components.
4.1. CPU Installation
- Locate the LGA1151 socket on the motherboard.
- Open the CPU socket lever and remove the protective cap.
- Carefully align the notches on your Intel 8th or 9th Gen CPU with the socket.
- Gently place the CPU into the socket without forcing it.
- Close the socket lever to secure the CPU.
4.2. Memory (RAM) Installation
- Identify the four DDR4 DIMM slots.
- Open the clips at both ends of the DIMM slot.
- Align the notch on the DDR4 memory module with the key in the DIMM slot.
- Press down firmly on both ends of the memory module until the clips snap into place.
4.3. M.2 SSD Installation
- Locate the M.2 slots on the motherboard.
- Remove the M.2 heatsink (if present) and the M.2 screw package.
- Insert the M.2 SSD into the slot at an angle.
- Gently push down the SSD and secure it with the provided screw.
- Reattach the M.2 heatsink if applicable.
4.4. Graphics Card (PCIe) Installation
- Identify the primary PCIe 3.0 x16 slot.
- Open the retention clip at the end of the slot.
- Align your graphics card with the slot and press down firmly until it is seated and the clip locks.
- Secure the card to your chassis with screws.
4.5. Power Supply and Front Panel Connections
Connect the 24-pin ATX power connector and the 8-pin CPU power connector from your power supply to the motherboard. Refer to the user guide for detailed diagrams of front panel header connections (power button, reset button, USB, audio).
5. Operating Instructions
5.1. First Boot and BIOS/UEFI Setup
Upon first power-on, the system will typically enter the BIOS/UEFI setup utility. Press the DEL or F2 key during startup to access the BIOS. Here you can configure boot order, system time, and other advanced settings. Ensure your memory's XMP profile is enabled for optimal performance.
5.2. Driver Installation
After installing your operating system, install the necessary drivers from the included Support DVD or download the latest versions from the official ASUS support website. This includes chipset drivers, LAN drivers, audio drivers, and any other utility drivers.
5.3. ASUS AI Overclocking and Aura Sync
The ROG Strix Z390-F Gaming Motherboard features 5-Way Optimization with AI Overclocking for intelligent system tuning. Utilize the ASUS AI Suite software to optimize performance and cooling. For customizable RGB lighting, use the ASUS Aura Sync software to synchronize effects across compatible components.

Image 5.1: ASUS Aura Sync logo, indicating RGB lighting synchronization capabilities.
6. Maintenance
Regular maintenance helps ensure the longevity and optimal performance of your motherboard.
6.1. Cleaning
Periodically clean dust from your computer case and motherboard using compressed air. Ensure the system is powered off and unplugged before cleaning. Avoid using liquid cleaners directly on components.
6.2. BIOS and Driver Updates
Keep your BIOS and drivers updated to the latest versions available on the ASUS support website. BIOS updates can improve compatibility, stability, and performance. Always follow the instructions provided by ASUS for BIOS updates carefully to avoid system damage.
7. Troubleshooting
If you encounter issues, refer to these common troubleshooting steps.
7.1. No Power / No Boot
- Check all power connections (24-pin ATX, 8-pin CPU) are securely seated.
- Ensure the power supply is switched on and functioning correctly.
- Verify the front panel power button connection to the motherboard.
7.2. No Display Output
- Confirm the monitor is connected to the graphics card (or motherboard if using integrated graphics) and powered on.
- Reseat the graphics card and memory modules.
- Try booting with only one RAM stick installed.
7.3. Component Not Detected
- Check physical connections for the component (e.g., SATA cables for drives, M.2 SSD seating).
- Ensure the component is enabled in the BIOS/UEFI settings.
- Update relevant drivers.
For more advanced troubleshooting, consult the detailed user manual on the Support DVD or visit the official ASUS support website.
8. Specifications
Key technical specifications for the ASUS ROG Strix Z390-F Gaming Motherboard:
| Feature | Specification |
|---|---|
| CPU Socket | LGA 1151 |
| Compatible Processors | 8th and 9th Generation Intel Core |
| Chipset | Intel Z390 |
| RAM Type | DDR4 |
| Memory Speed | Up to 2400 MHz (and higher with OC) |
| Max RAM Capacity | 32 GB (per module, total depends on configuration) |
| Storage | Dual M.2, SATA 6Gb/s |
| USB Ports | USB 3.1 Gen 2, USB 3.1 Gen 1, USB 2.0 |
| LAN | Gigabit LAN |
| Audio | 8-Channel HD Audio (ROG exclusive SupremeFX S1220A) |
| Dimensions (LxWxH) | 12 x 9.6 x 2 inches (ATX Form Factor) |
9. Warranty and Support
For warranty information, please refer to the warranty card included in your product package or visit the official ASUS website. ASUS provides technical support and resources to assist with any product-related inquiries.
ASUS Support Website: www.asus.com/support/





