1. Introduction
The ASUS Prime Z390-A Motherboard is engineered for 8th and 9th generation Intel Core processors, offering a robust platform for high-performance computing. This manual provides essential information for the proper installation, operation, and maintenance of your motherboard, ensuring stable and efficient system performance.
Official product overview video for the ASUS Prime Z390-A Motherboard, highlighting its key features and design.
2. Package Contents
Verify that all items are present in your motherboard package:
- PRIME Z390-A motherboard
- Serial ATA 6.0Gb/s cables (3)
- SLI™ HB Bridge (2-WAY-M)
- ASUS Q-Shield
- Q-connector
- M.2 screw package
- CPU FAN Holder
- Support DVD
- User's manual
3. Key Features
- Processor Support: Designed for 9th and 8th generation Intel Core processors, maximizing connectivity and speed.
- Memory Optimization: Features M.2, USB 3.1 Gen2, and ASUS OptiMem II for improved DRAM overclocking stability.
- 5-Way Optimization: AI overclocking and dynamic fan calibration for balanced performance.
- Enhanced Durability: 5X Protection III with SafeSlot Core, LANGuard, and Overvoltage Protection ensures longevity and reliability.
- Advanced Cooling: FanXpert 4 delivers advanced fan control for dynamic system cooling.
- Fortified PCIe Slots: Patent-pending SafeSlot Core prevents damage from heavyweight GPUs.
- High-Definition Audio: 8-channel HD Gaming Audio featuring Realtek ALC887 codec.
- Customizable Lighting: Aura Sync RGB with addressable headers for personalized aesthetics.
4. Setup and Installation
Follow these steps for proper installation of your ASUS Prime Z390-A Motherboard into your PC case.
4.1 Motherboard Overview

This image shows a top-down view of the ASUS Prime Z390-A Motherboard, highlighting the CPU socket, RAM slots, PCIe slots, and various headers.
4.2 Installing the CPU
Carefully open the CPU socket lever, align the CPU with the socket's notch, and gently place it into the socket. Close the lever to secure the CPU. Ensure the CPU is correctly oriented to avoid damage.

A close-up view of the LGA1151 CPU socket and the four DDR4 RAM slots on the motherboard.
4.3 Installing RAM
Open the clips on the DDR4 memory slots. Align your RAM modules with the slots, ensuring the notch on the module matches the slot. Press firmly on both ends until the clips snap into place. Refer to your motherboard manual for recommended dual-channel configurations.
4.4 Installing M.2 Drives
Locate the M.2 slots on the motherboard. Remove the M.2 screw and standoff. Insert your M.2 drive at an angle into the slot, then push it down and secure it with the screw. The Prime Z390-A features dual M.2 slots for high-speed storage.
4.5 Installing Graphics Card and Other PCIe Devices
Insert your graphics card into the primary PCIe x16 slot (usually the top one). Ensure it is seated firmly and secure it with the case screw. Install any other PCIe expansion cards into the available slots as needed.
4.6 Connecting Power Supply
Connect the 24-pin ATX power connector and the 8-pin (or 4+4-pin) CPU power connector from your power supply to the corresponding ports on the motherboard. Connect SATA power cables to your storage drives and PCIe power cables to your graphics card.
4.7 Connecting Front Panel and I/O
Connect the front panel headers (power switch, reset switch, HDD LED, power LED) to the motherboard. Connect USB 2.0, USB 3.0, and audio headers. Finally, connect your monitor to the graphics card or the motherboard's integrated graphics ports (DisplayPort, HDMI).

This image displays the rear I/O panel of the ASUS Prime Z390-A Motherboard, showing various ports including USB, Ethernet, DisplayPort, HDMI, and audio jacks.
5. Operating Instructions
5.1 First Boot and BIOS Setup
Upon first power-on, your system will likely enter the BIOS (Basic Input/Output System). Here, you can configure boot order, enable XMP for RAM, adjust fan curves, and perform initial system checks. Save and exit the BIOS to proceed with operating system installation.
5.2 Driver Installation
After installing your operating system, install the necessary drivers from the included support DVD or download the latest versions from the ASUS official website. Key drivers include chipset, LAN, audio, and graphics drivers for optimal performance and functionality.
5.3 ASUS AI Suite 3 and Aura Sync
Utilize ASUS AI Suite 3 for system monitoring, fan control, and AI overclocking. For customizable RGB lighting, use the Aura Sync software to synchronize lighting effects across compatible components connected to the motherboard's RGB headers.
6. Maintenance
Regular maintenance ensures the longevity and stable performance of your motherboard and PC system.
- Dust Removal: Periodically clean dust from the motherboard, CPU cooler, and case fans using compressed air. Ensure the system is powered off and unplugged before cleaning.
- BIOS Updates: Check the ASUS support website for the latest BIOS updates. BIOS updates can improve compatibility, stability, and performance. Follow the update instructions carefully.
- Driver Updates: Keep all system drivers updated to ensure compatibility and optimal performance with new software and hardware.
- Cable Management: Ensure internal cables are neatly managed to improve airflow and prevent interference.
7. Troubleshooting
This section addresses common issues you might encounter:
| Problem | Possible Solution |
|---|---|
| System does not power on | Check all power connections (24-pin ATX, 8-pin CPU, GPU power). Ensure the power supply switch is on. Verify front panel power button connection. |
| No display on monitor | Ensure monitor is connected to the graphics card (not motherboard I/O if a dedicated GPU is installed). Reseat the graphics card and RAM modules. Check monitor input source. |
| System boots but crashes or freezes | Check CPU and GPU temperatures. Verify RAM is correctly seated and compatible. Update BIOS and drivers. Run memory diagnostic tools. |
| Slow performance | Ensure all drivers are installed. Check for background processes. Verify storage drive health. Consider enabling XMP for RAM in BIOS. |
| RGB lighting not working or incorrect | Ensure RGB headers are correctly connected. Install and configure ASUS Aura Sync software. Check for conflicts with other RGB software. |
8. Specifications
| Feature | Detail |
|---|---|
| CPU Socket | LGA 1151 |
| Compatible Processors | 8th Generation Intel Core, 9th Generation Intel Core |
| Chipset | Intel Z390 |
| RAM Memory Technology | DDR4 SDRAM |
| Memory Speed | 2400 MHz (Supports higher via overclocking) |
| M.2 Slots | 2 |
| USB 3.1 Gen2 Ports | Yes |
| Gigabit LAN | Yes |
| Audio | Realtek ALC887 8-Channel High Definition Audio CODEC |
| Form Factor | ATX |
| Product Dimensions | 12.91 x 2.68 x 10.35 inches |
| Item Weight | 2.23 pounds |
9. Warranty and Support
For detailed warranty information, please refer to the warranty card included in your product package or visit the official ASUS support website. ASUS provides comprehensive technical support and resources for its products.
You can find additional support, driver downloads, and FAQs on the ASUS Store on Amazon.





