1. Introduction
This manual provides comprehensive instructions for the installation, operation, maintenance, and troubleshooting of your ASUS uATX X99-M WS motherboard. Designed for high performance and reliability, this microATX board integrates advanced features such as 5-Way Optimization, ASUS OC Socket, USB 3.1, and 802.11ac Wi-Fi, complemented by server-grade components for enhanced stability.
2. Setup
Proper installation is crucial for optimal performance. Follow these steps carefully:
- Prepare the Chassis: Ensure your computer chassis is compatible with the microATX form factor. Install standoffs in the appropriate locations within the chassis.
- Install the CPU: Carefully align your LGA 2011-3 CPU with the OC Socket on the motherboard. Lower the CPU into the socket, ensuring it is seated correctly, then secure it with the retention levers.
- Install the CPU Cooler: Apply thermal paste to the CPU and install the compatible CPU cooler according to its manufacturer's instructions. Connect the CPU fan cable to the CPU_FAN header on the motherboard.
- Install Memory Modules (RAM): This motherboard supports DDR4 RAM. Insert the memory modules into the DIMM slots (DIMM_A1, DIMM_B1, DIMM_C1, DIMM_D1) by aligning the notch on the module with the key in the slot and pressing down firmly until the clips lock into place. Refer to the motherboard layout for recommended dual-channel or quad-channel configurations.
- Mount the Motherboard: Carefully place the motherboard into the chassis, aligning the screw holes with the installed standoffs. Secure the motherboard using screws.
- Connect Power Supply: Connect the 24-pin ATX power connector (EATXPWR) and the 8-pin ATX 12V power connector (EATX12V) from your power supply unit (PSU) to the corresponding headers on the motherboard.
- Install Expansion Cards: Insert your PCI Express 3.0 x16 graphics cards or other expansion cards into the appropriate PCIEX16 slots. Ensure they are fully seated and secured with the chassis retention mechanism.
- Connect Storage Devices: Connect SATA data cables from your storage drives (HDDs/SSDs) to the SATA 6Gb/s ports on the motherboard. If using an M.2 SSD, install it into the M.2 Support slot and secure it.
- Connect Front Panel Cables: Connect the power button, reset button, HDD LED, power LED, and front panel USB/audio connectors from your chassis to the corresponding headers on the motherboard. Pay close attention to polarity for LEDs.
- Connect Peripherals: Connect your monitor, keyboard, mouse, and other peripherals to the appropriate ports on the motherboard's rear I/O panel.

Figure 1: Overview of the ASUS uATX X99-M WS Motherboard. Key components visible include the LGA 2011-3 CPU socket, DDR4 DIMM slots, PCI Express x16 slots, M.2 support, SATA 6Gb/s ports, and various power connectors and headers. The integrated Wi-Fi module and Crystal Sound 2 audio components are also highlighted.
3. Operating
Once all components are installed and connected, you can power on your system:
- Power On: Ensure the power supply switch is in the 'ON' position. Press the power button on your computer chassis. The system should initiate the boot process.
- BIOS/UEFI Setup: During startup, press the designated key (usually DEL or F2) to enter the BIOS/UEFI setup utility. Here, you can configure system settings, boot order, and enable features like ASUS 5-Way Optimization for performance tuning.
- Operating System Installation: Install your preferred operating system (e.g., Windows 10) by booting from an installation media (USB drive or DVD).
- Driver Installation: After OS installation, install the latest drivers for your motherboard components (chipset, audio, LAN, Wi-Fi, USB 3.1) from the ASUS support website or the provided driver disc.
4. Maintenance
Regular maintenance helps ensure the longevity and stable operation of your motherboard:
- Dust Removal: Periodically clean dust from the motherboard and components using compressed air. Accumulation of dust can lead to overheating and reduced performance.
- Component Inspection: Visually inspect all connections and components for any signs of wear, damage, or loose connections.
- BIOS/UEFI Updates: Check the ASUS support website for the latest BIOS/UEFI updates. Updates can improve system stability, compatibility, and performance. Follow the update instructions provided by ASUS carefully.
5. Troubleshooting
If you encounter issues, consider the following common troubleshooting steps:
- No Power/No Boot:
- Ensure all power cables (24-pin ATX, 8-pin ATX 12V) are securely connected to the motherboard and PSU.
- Verify the power supply switch is in the 'ON' position.
- Check front panel connections, especially the power button header.
- Reseat RAM modules. Incorrectly seated RAM is a common cause of no-boot issues.
- Check the Q-Code LED on the motherboard for diagnostic codes that can indicate the source of the problem.
- System Instability/Crashes:
- Ensure all drivers are up-to-date.
- Check CPU and GPU temperatures. Overheating can cause instability.
- Test memory modules individually to identify a faulty stick.
- Reset BIOS settings to default.
- Peripheral Not Detected:
- Ensure the peripheral is properly connected to the correct port.
- Install or update relevant drivers for the peripheral.
- Test the peripheral on another system or try a different port on your motherboard.
6. Specifications
| Feature | Detail |
|---|---|
| Brand | ASUS |
| Model Name | X99-M WS |
| CPU Socket | LGA 2011-3 |
| RAM Memory Technology | DDR4 |
| RAM Memory Maximum Size | 64 GB |
| Chipset Type | Intel X99 |
| Graphics Card Interface | PCI Express |
| Wireless Type | Bluetooth, 802.11ac Wi-Fi |
| Product Dimensions | 13.14 x 3 x 11.34 inches |
| Item Weight | 2.45 pounds |
7. Warranty and Support
For warranty information and technical support, please refer to the official ASUS website or contact ASUS customer service. A detailed User Manual (PDF) is also available for download from the product's support page, providing in-depth information on advanced configurations and features.
Note: The official User Manual (PDF) can be found at: ASUS X99-M WS User Manual (PDF)





