1. Introduction
The Eppendorf ThermoMixer C is a laboratory device designed for precise temperature control and efficient mixing of samples. It facilitates simultaneous heating, mixing, and cooling across various vessel and plate formats, ranging from 5 µL to 50 mL. This basic device requires a compatible SmartBlock (sold separately) for operation. Key features include the 2DMix-Control technology for excellent mixing performance, high-speed mixing capabilities up to 3,000 rpm, precise temperature control, and anti-spill technology to prevent condensation and cross-contamination.
2. Safety Information
Always read and understand this manual before operating the device. Observe all safety precautions to prevent injury and damage to the equipment.
- Electrical Safety: Ensure the device is connected to a grounded power outlet with the correct voltage. Do not operate with damaged power cords.
- Temperature Hazards: Surfaces may become hot during operation. Use caution when handling SmartBlocks and samples.
- Chemical Safety: Handle samples and reagents according to laboratory safety guidelines. Clean spills immediately.
- Proper Placement: Place the device on a stable, level surface away from flammable materials and direct sunlight. Ensure adequate ventilation.
- Authorized Personnel: Only trained personnel should operate this device.
3. Package Contents
Verify that all items are present and undamaged upon unpacking:
- Eppendorf ThermoMixer C basic device (Model 5382000023)
- Power cord
- Instruction Manual
Note: A compatible Eppendorf SmartBlock is required for operation and is sold separately.
4. Setup
- Unpacking: Carefully remove the device from its packaging. Retain packaging for future transport or storage.
- Placement: Position the ThermoMixer C on a clean, stable, and level laboratory bench. Ensure sufficient space around the device for ventilation.
- Power Connection: Connect the power cord to the device's power inlet and then to a grounded electrical outlet.
- SmartBlock Installation: The ThermoMixer C requires a SmartBlock for sample processing. To install, align the SmartBlock with the recess on the device and gently press down until it clicks into place. Ensure it is securely seated.

An image showing the Eppendorf 5382000023 ThermoMixer C, a compact laboratory device with a control panel and a slot for a SmartBlock.
5. Operating Instructions
This section describes the basic operation of the ThermoMixer C.
- Power On: Press the power button located on the device. The display will illuminate.
- Insert Samples: Place your samples in the appropriate vessels (e.g., tubes, plates) and insert them into the installed SmartBlock. Ensure vessels are properly sealed to prevent spills.
- Set Temperature: Use the control panel to set the desired incubation temperature. The device offers excellent temperature control and precision.
- Set Mixing Speed: Adjust the mixing speed (rpm) as required for your application. The ThermoMixer C supports high-speed mixing up to 3,000 rpm, suitable for various sample types and plate formats.
- Start Program: Select and start the desired program or manual operation. The unique 2DMix-Control technology ensures thorough and uniform mixing.
- Anti-Spill Technology: The device incorporates anti-spill technology to minimize condensation on the lid and prevent cross-contamination, ensuring sample integrity.
- Monitoring: Monitor the process via the display.
- End Program: Once the program is complete, carefully remove your samples.
- Power Off: Press the power button to turn off the device when not in use.
6. Maintenance
Regular maintenance ensures optimal performance and longevity of your ThermoMixer C.
- Cleaning: Disconnect the device from power before cleaning. Wipe exterior surfaces with a soft, damp cloth and a mild detergent. Do not use abrasive cleaners or solvents.
- SmartBlock Cleaning: Remove the SmartBlock for cleaning. It can be cleaned separately with appropriate laboratory detergents. Ensure it is dry before reinstallation.
- Inspection: Periodically inspect the power cord for damage. Check the SmartBlock seating for any debris that might hinder proper contact.
- Storage: Store the device in a clean, dry environment when not in use.
7. Troubleshooting
Refer to this section for common issues and their solutions.
- Device does not power on:
- Check power cord connection to the device and the electrical outlet.
- Verify the electrical outlet is functional.
- Mixing is not occurring:
- Ensure a SmartBlock is correctly installed.
- Check if the mixing function is activated in the program settings.
- Verify the set mixing speed is above zero.
- Temperature is not stable or incorrect:
- Ensure the SmartBlock is properly seated.
- Check the set temperature against the actual temperature displayed.
- Ensure the ambient temperature is within the device's operating range.
- Error message on display:
- Note the error code and consult the full technical manual or contact customer support.
If the issue persists after attempting these solutions, contact Eppendorf customer support.
8. Specifications
| Specification | Value |
|---|---|
| Manufacturer | Eppendorf |
| Part Number | 5382000023 |
| Wattage | 200 watts |
| Temperature Range | 1/100 Degrees Celsius (Note: This likely refers to precision or increment, not the full operating range. Refer to full technical documentation for exact range.) |
| Weight | 566.99 g (1.25 Pounds) |
| Model Number | 5382000023 |
| Batteries Required | No |
9. Warranty and Support
For information regarding product warranty, service, or technical support, please refer to the official Eppendorf website or contact your local Eppendorf representative. Keep your purchase receipt and serial number handy when contacting support.