Introduction
The ASHRAE Laboratory Design Guide, 2nd Edition, serves as a comprehensive reference manual for the planning, design, and operation of laboratories. This guide is intended for engineers, owners, and system operators involved in laboratory environments.
Its primary objective is to provide strategies for reducing the laboratory's energy footprint while simultaneously ensuring safety, maintaining good comfort and indoor air quality, and protecting the integrity of laboratory experiments.

Image: Front cover of the ASHRAE Laboratory Design Guide, 2nd Edition. This image displays the book's title, "The Complete Laboratory HVAC Resource," and the ASHRAE logo, indicating its focus on laboratory HVAC systems.
Key Content Areas
The guide is structured to follow a typical project progression, covering the fundamental stages of planning, design, construction, operation, and maintenance. It provides essential background information on various laboratory types and their associated equipment, offering a foundational understanding of their functions and requirements.
Key topics addressed within the manual include:
- Exhaust Hoods: Design and operational considerations.
- Primary Air Systems: Principles and applications.
- Process Cooling: Techniques and system integration.
- Air Treatment: Methods for maintaining air quality.
- Exhaust Stack Design: Best practices for contaminant dispersion.
- Airflow Patterns and System Balancing: Ensuring proper ventilation and control.
- Energy Recovery: Strategies for improving energy efficiency.
- Laboratory Commissioning Process: Procedures for verifying system performance.
- Economics: Analysis of both initial and life-cycle costs.
Dedicated chapters offer guidance for specialized laboratories, including those requiring biological containment and animal research. These sections cover critical aspects such as envelope design, system reliability, redundancy, proper space pressurization, biohazard containment and control, product protection, and sanitation.
Updates in the 2nd Edition
This second edition incorporates current industry standards and practices. Notable additions include two new chapters:
- High-Performance Building Design: Concepts for achieving sustainability in laboratory environments.
- Airflow and Contaminant Evaluation: Guidelines for assessing airflow patterns and contaminant concentrations using computational fluid dynamics (CFD) computer modeling.
The guide also features expanded web links to relevant industry standards and resources, along with design tools designed to illustrate laboratory features and provide practical design aids.
Specifications
| Publisher | Ashrae |
| Publication Date | August 1, 2015 |
| Edition | 2nd |
| Language | English |
| Print Length | 328 pages |
| ISBN-10 | 1936504987 |
| ISBN-13 | 978-1936504985 |
| Item Weight | 2.32 pounds |
| Dimensions | 8.5 x 0.75 x 10.5 inches |
Support and Contact Information
For further information or inquiries regarding the ASHRAE Laboratory Design Guide, please contact ASHRAE directly:
- Address: 1791 Tullie Circle, Atlanta, GA 30329-2305, USA
- Phone: 404-636-8400 (worldwide)
- Website: www.ashrae.org